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IL1B

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Eumetopias jubatus
Length
270 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
30.887 kDa
Sequence
MATVPEPTSEMMSYYYSDNENDLFFEADGPRKMKCCFQDLNNSSLEDEGIQLHISHQLHNKSLKHFVSVVVALEKLKKVSLPCSQPLQDDDLKNIFCCIFEEEPIVCEVYDDDAFVCDAPLQSLDCKFRDISQKSLVLYNSCELRALHLNGSSVNQQAVFRMSFVQGDENSNKIPVALCIKEKNLYLSCVMKDGKPTLQLEMLDPRVYPKKKMEKRFVFNKTEIKETLEFESSQFPNWYISTSKAEAMPVFLGNTKGGQDITDFTMELSS

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Mustela putorius furo
Length
270 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
30.982 kDa
Sequence
MARVPEPTSEVMSYGYSDNENDLFFEADGPGKMKCCFQDLNNSYLEEEGIQLQISHQLHNKSLSHFVSVIVALEKLKKISVPCSLPLQGDDLMNVFHCIFEEEPIILEKCDDNAFVHDAPPRSLDCKFQDINQKSLVLYNSYELRALHLNGTSVNQQAVFRMTFVQEDEDITKIPVALCIKEKNLYLSCVMKDGKPTLQLEMLDPKVYPKKRMEKRFVFNKTEIKKKVEFESSQFPNWYISTSQAEAMPVFLGNNRGGHDITDFTMELSS

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Phoca vitulina richardii
Length
270 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
31.053 kDa
Sequence
MATVPEPTSEMMSYYYSDNENDLFFEADGPRKMKCCFQDLNNSSLKDEGIQLHISHQLQNKSLRHFVSVVVALEKLKKISLPCSQPLQDDDLKNVFCCIFEEEPIVCEVYDDDAFVCDAPLQSLDCKFRDKNQKSLVLYNSYELRALHLNGSSVNQQAVFRMSFLQGDENSNKIPVALCIKEKNLYLSCVMKDGKPTLQLEMLDPRVYPKKKMEKRFVFNKTEVKKILEFESSQFPNWYISTSKAEAMPVFLGNTKGGQDITDFTMEFSS

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Pusa hispida
Length
270 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
31.053 kDa
Sequence
MATVPEPTSEMMSYYYSDNENDLFFEADGPRKMKCCFQDLNNSSLKDEGIQLHISHQLQNKSLRHFVSVVVALEKLKKISLPCSQPLQDDDLKNVFCCIFEEEPIVCEVYDDDAFVCDAPLQSLDCKFRDKNQKSLVLYNSYELRALHLNGSSVNQQAVFRMSFLQGDENSNKIPVALCIKEKNLYLSCVMKDGKPTLQLEMLDPRVYPKKKMEKRFVFNKTEVKKILEFESSQFPNWYISTSKAEAMPVFLGNTKGGQDITDFTMEFSS

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Cercocebus atys
Length
269 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
30.445 kDa
Sequence
MAEVPELASEMMAYYSSNEDDLFFEVDGPKQMKCSFQDLDLCPLDGGIQLQISHEHYNKGFRQAVSVVVAMEKLRKMLVPCPQTFQDNDLSTLIPFIFEEEPVFLDTCNNDACVHDAPVRSLHCTLRDAQLKSLVMSGPYELKALHLQGQDVEQQVVFSMSFVQGEESNDKVPVALGLKAKNLYLSCVLKDDKPTLQLESVDPKNYPKKKMEKRFVFNKIEINNKLECESAQFPNWYISTSQAENMPVFLGGTRGGQDITDFTMQFVSS

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Homo sapiens
Length
269 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells (PubMed:10653850).
Similarity
Belongs to the IL-1 family.
Mass
30.748 kDa
Sequence
MAEVPELASEMMAYYSGNEDDLFFEADGPKQMKCSFQDLDLCPLDGGIQLRISDHHYSKGFRQAASVVVAMDKLRKMLVPCPQTFQENDLSTFFPFIFEEEPIFFDTWDNEAYVHDAPVRSLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEESNDKIPVALGLKEKNLYLSCVLKDDKPTLQLESVDPKNYPKKKMEKRFVFNKIEINNKLEFESAQFPNWYISTSQAENMPVFLGGTKGGQDITDFTMQFVSS

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Macaca mulatta
Length
269 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
30.481 kDa
Sequence
MAEVPELASEMMAYYSGNEDDLFFDVDGPKQMKCSFQDLDLCPLGGGIQLQISHEHYNEGFRQAVSVVVAMEKLRKMLVPCPQIFQDNDLSTLIPFIFEEEPVFLDTRNNDACVHDAPVRSLHCTLRDAQLKSLVMSGPYELKALHLQGQDLEQQVVFSMSFVQGEESNDKIPVALGLKAKNLYLSCVLKDDKPTLQLESVDPKNYPKKKMEKRFVFNKIEINNKLEFESAQFPNWYISTSQAENMPVFLGGTRGGQDITDFTMQFVSS

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Macaca nemestrina
Length
269 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
30.612 kDa
Sequence
MAEVPELASEMMAYYSGNEDDLFFEVDGPKQMKCSFQDLDLCPLDGGIQLQISHEHYNKGFRQAVSVVVAMEKLRKMLVPCPQIFQDNDLSTLIPFIFEEEPVFLDTRNNDACVHDAPVRSLHCTLRDAQLKSLVMSGPYELKALHLQGQDLEQQVVFFMSFVQGEESNDKIPVALGLKAKNLYLSCVLKDDKPTLQLESVDPKNYPKKKMEKRFVFNKIEINNKLEFESAQFPNWYISTSQAENMPVFLGGTRGGQDITDFTMQFVSS

Gene
Il1b
Protein
Interleukin-1 beta
Organism
Mus musculus
Length
269 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
30.931 kDa
Sequence
MATVPELNCEMPPFDSDENDLFFEVDGPQKMKGCFQTFDLGCPDESIQLQISQQHINKSFRQAVSLIVAVEKLWQLPVSFPWTFQDEDMSTFFSFIFEEEPILCDSWDDDDNLLVCDVPIRQLHYRLRDEQQKSLVLSDPYELKALHLNGQNINQQVIFSMSFVQGEPSNDKIPVALGLKGKNLYLSCVMKDGTPTLQLESVDPKQYPKKKMEKRFVFNKIEVKSKVEFESAEFPNWYISTSQAEHKPVFLGNNSGQDIIDFTMESVSS

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Trichosurus vulpecula
Length
269 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
31.141 kDa
Sequence
MAMVPEITCDEVDFYRDDDDRQFYEADGPNQKKGYFQYPDLCSKESLLEEDGIQLKFTTQPHQFHQTVMVIVAIEKMKHLNGLSSQFFQDNDLMNIFTNIFQEEPITFKNCDIYESDSSFRLVSSQDCTIQDINQKCLALSKASELRALHLNGRNISQQVIFSMKYLLGDIGSQKTHVVLCIKKNNLYLSCVRRGEKPILQLEQIANFPSINVEKRFIFNKVEINNTTEFESAEYPNWYISTSQMDEQPVFLGNIRGGKDITDFILADF

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Equus caballus
Length
268 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
30.268 kDa
Sequence
MAAVPDTSDMMTYCSGNENDLFFEEDGPKQMKGSFQDLDLSSMGDGGIQLQFSHHLYNKTFKHAMSIIVAVEKLKKIPVPCSQAFQDDDLRSLFSVIFEEEPIICDNWDEGYVCDAAMHSVNCRLRDIYHKSLVLSGACELQAVHLNGENTNQQVVFCMSFVQGEEETDKIPVALGLKEKNLYLSCGMKDGKPTLQLETVDPNTYPKRKMEKRFVFNKMEIKGNVEFESAMYPNWYISTSQAEKSPVFLGNTRGGRDITDFIMEITSA

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Macaca fascicularis
Length
268 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
30.425 kDa
Sequence
MAEVPELASEMMAYYSGNEDDLFFDVDGPKQMKCSFQDLDLCPLDGGIQLQISHEHYNEGFRQAVSVVVAMEKLRKMLVPCPQIFQDNDLSTLIPFIFEEEPVFLDTRNNDACVHDAPVRSLHCTLRDAQLKSLVMSGPYELKALHLQGQDLEQQVVFSMSFVQGEESNDKIPVALGLKAKNLYLSCVLKDDKPTLQLESVDPKNYPKKKMEKRFVFNKIEINNKLEFESAQFPNWYISTSQAESMPVFLGGTRGGQDITDFTMQFVS

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Oryctolagus cuniculus
Length
268 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
30.665 kDa
Sequence
MATVPELTSEMMAYHSGNENDLFFEADGPNYMKSCFQDLDLCCPDEGIQLRISCQPYNKSFRQVLSVVVALEKLRQKAVPCPQAFQDDGLRTFFSLIFEEEPVLCNTWDDYSLECDAVRSLHCRLQDAQQKSLVLSGTYELKALHLNAENLNQQVVFSMSFVQGEESNDKIPVALGLRGKNLYLSCVMKDDKPTLQLESVDPNRYPKKKMEKRFVFNKIEIKDKLEFESAQFPNWYISTSQTEYMPVFLGNNSGGQDLIDFSMEFVSS

Gene
Il1b
Protein
Interleukin-1 beta
Organism
Rattus norvegicus
Length
268 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
30.644 kDa
Sequence
MATVPELNCEIAAFDSEENDLFFEADRPQKIKDCFQALDLGCPDESIQLQISQQHLDKSFRKAVSLIVAVEKLWQLPMSCPWSFQDEDPSTFFSFIFEEEPVLCDSWDDDDLLVCDVPIRQLHCRLRDEQQKCLVLSDPCELKALHLNGQNISQQVVFSMSFVQGETSNDKIPVALGLKGLNLYLSCVMKDGTPTLQLESVDPKQYPKKKMEKRFVFNKIEVKTKVEFESAQFPNWYISTSQAEHRPVFLGNSNGRDIVDFTMEPVSS

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Felis catus
Length
267 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
30.362 kDa
Sequence
MAPVPELTSEMMAYYSDENDLFFEADGPEKMKGSLQNLSHSFLGDEGIQLQISHQPDNKSLRHAVSVIVAMEKLKKISFACSQPLQDEDLKSLFCCIFEEEPIICDTWDDGFVCDAAIQSQDYTFRDISQKSLVLSGSYELRALHLNGQNMNQQVVFRMSFVHGEENSKKIPVVLCIKKNNLYLSCVMKDGKPTLQLEMLDPKVYPKKKMEKRFVFNKTEIKGNVEFESSQFPNWYISTSQAEEMPVFLGNTKGGQDITDFIMESAS

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Lama glama
Length
267 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
30.521 kDa
Sequence
MATVPEPTSEMMAYYSDNDNDLLFEADGPKQRKCCVQPPDLGSLGDEGIQLQISHQLYNKSFRQVVSLIVAMEKLSKCTYSQYFQDDDLRNIFSLIFEEEPVTFETCADDFVCDAVVQSLYCKLQDKEQKSMVLASPYVLQALHLLAQDMSREVVFCMSFVQGDENNSKTPVVLGLKEKNLYLSCVMKGDKPTLQLEALDPKSYPRKNMEKRFVFYKTEIKDRVEFESALYPNWYISTSTAEQRPVFLGQSRGGQDITDFTMETLSP

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Sus scrofa
Length
267 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
30.404 kDa
Sequence
MAIVPEPAKEVMANYGDNNNDLLFEADGPKEMKCCTQNLDLGSLRNGSIQLQISHQLWNKSIRQMVSVIVAVEKPMKNPSSQAFCDDDQKSIFSFIFEEEPIILETCNDDFVCDANVQSMECKLQDKDHKSLVLAGPHMLKALHLLTGDLKREVVFCMSFVQGDDSNNKIPVTLGIKGKNLYLSCVMKDNTPTLQLEDIDPKRYPKRDMEKRFVFYKTEIKNRVEFESALYPNWYISTSQAEQKPVFLGNSKGRQDITDFTMEVLSP

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Bos taurus
Length
266 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
30.76 kDa
Sequence
MATVPEPINEMMAYYSDENELLFEADDPKQMKSCIQHLDLGSMGDGNIQLQISHQFYNKSFRQVVSVIVAMEKLRNSAYAHVFHDDDLRSILSFIFEEEPVIFETSSDEFLCDAPVQSIKCKLQDREQKSLVLASPCVLKALHLLSQEMNREVVFCMSFVQGEERDNKIPVALGIKDKNLYLSCVKKGDTPTLQLEEVDPKVYPKRNMEKRFVFYKTEIKNTVEFESVLYPNWYISTSQIEERPVFLGHFRGGQDITDFRMETLSP

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Bubalus carabanensis
Length
266 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
30.627 kDa
Sequence
MATVPEPINEMMAYYSDENELLFEADGPKQMKSCIQHLDLGSMGDGNIQLQISHQLYNKSFRQVVSVIVAMEKLRNSAYAHVFHDDDLRSILSFIFEEEPVIFETSSDEFLCDAPVQSVKCKLQDREQKSLVLASPCVLKALHLLSQEMSREVVFCMSFVQGEERDNKIPVALGIKDKNLYLSCVKKGDTPTLQLEEVDPKVYPKRNMEKRFVFYKTEIKNTVEFESVLYPNWYISTSQIEERPVFLGHFRGGQDITDFRMETLSP

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Canis lupus familiaris
Length
266 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
30.259 kDa
Sequence
MAAVPELTSEMMAYSSNNENDLFFEADGPGNDVKCCCQDLNHSSLVDEGIQLQVSHQLCNKSLRHFVSVIVALEKLKKPCPQVLQEDDLKSIFCYIFEEEPIICKTDADNFMSDAAMQSVDCKLQDISHKYLVLSNSYELRALHLNGENVNKQVVFHMSFVHGDESNNKIPVVLGIKQKNLYLSCVMKDGKPTLQLEKVDPKVYPKRKMEKRFVFNKIEIKNTVEFESSQYPNWYISTSQVEGMPVFLGNTRGGQDITDFTMEFSS

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Capra hircus
Length
266 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
30.769 kDa
Sequence
MATVPEPINEVMAYYSDENELLFEADGPKQMKSCTQHLDLGSMGDGNIQLQISHQLYNKSFRQVVSVIVAMEKLRSRAYEHVFRDDDLRSILSFIFEEEPVIFETSSDELLCDAAVQSVKCKLQDREQKSLVLDSPCVLKALHLLSQEMSREVVFCMSFVQGEERDNKIPVALGIRDKNLYLSWVKKGDTPTLQLEEVDPKVYPKRNMEKRFVFYKTEIKNTVEFESVLYPNWYISTSQIEEKPVFLGHFRGGQDITDFRMETLSP

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Cavia porcellus
Length
266 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
30.531 kDa
Sequence
MAAVPELSSEVTAYHSDENELFFEVDGPNKMQYCFQDRDLCSLDEGIKLQISHQHFNKSFRQTVSLIVAVEKLRKKLAPCTWAFQDDDLRPLLPFIFEEEPIVCDTWDEEYESDTPVPSRNCTLHDIQHKRLVLSDPCELKALHLNGDNLNRQVVFSMSFVQGERSDNKMPVALGLKGKNLYLSCVMKDGKPVLQLESVDGKQYPKKKMEKRFVFNKITSKSTVEFESAQFPNWYISTSQAEHKPVFLGNNNGQDIIDFKLELVSS

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Cervus elaphus
Length
266 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
30.629 kDa
Sequence
MAPVPEPINEMMAYYSDENELLFEADGPKQMKSCIQHLDLGSVEVGNIQLQISHQLYNKSFRQVVSVIVAMEKLRNSAYAHVFHDDDLRNVLSFIFEEEPVIFETSSDEFLCDAAVQSVNCKLQDREQNSLVLASPCVLKALHLLSQEMSREVVFCMSFVQAEERDNKIPVALGIRDKNQYLSCVKKGDTPTLQLEEVDPKVYPKRNMEKRFVFYKTEIKDTVEFESVLYPNWYISTSHPEEKPVFLGHFRGGQDITDFRMETLSP

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Delphinapterus leucas
Length
266 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
30.219 kDa
Sequence
MATVPEPTNEVMAYYSDENDLLFEADGPKQMKCCVQPLDLNSMGDGSIHLQISHQLYNKSLRRVVSVIVAVEKLQKIPCSQTFQDDGLRSIFSLIFEEEPVIFETYDDDLLCDAGVQSLTCKLQDRDQKSLVLASPCVLKALHLLARDVNREVVFCMSFVQGDESNDKIPVALGLKEKNLYLSCVMKGDRPTLQLEEVDPKTYPKWKMEKRFVFNKTEIKNSVEFESALYPNWYISTSQAEEKPIFLGRSKGGHDITDFTMEIISP

Gene
IL1B
Protein
Interleukin-1 beta
Organism
Ovis aries
Length
266 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.
Similarity
Belongs to the IL-1 family.
Mass
30.717 kDa
Sequence
MATVPEPINEVMAYYSDENELLFEVDGPKQMKSCTQHLDLGSMGDGNIQLQISHQLYNKSFRQVVSVIVAMEKLRSRAYEHVFRDDDLRSILSFIFEEEPVIFETSSDELLCDAAVQSVKCKLQDREQKSLVLDSPCVLKALHLPSQEMSREVVFCMSFVQGEERDNKIPVALGIRDKNLYLSCVKKGDTPTLQLEEVDPKVYPKRNMEKRFVFYKTEIKNTVEFESVLYPNWYISTSQIEEKPVFLGRFRGGQDITDFRMETLSP

Gene
il1b
Protein
Interleukin-1 beta
Organism
Oncorhynchus mykiss
Length
260 amino acids
Function
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production.
Similarity
Belongs to the IL-1 family.
Mass
29.127 kDa
Sequence
MDFESNYSLIKNTSESAAWSSKLPQGLDLEVSHHPITMRHIANLIIAMERLKGGEGVTMGTEFKDKDLLNFLLESAVEEHIVLELESAPPASRRAAGFSSTSQYECSVTDSENKCWVLMNEAMELHAMMLQGGSSYHKVHLNLSSYVTPVPIETEARPVALGIKGSNLYLSCSKSGGRPTLHLEEVADKDQLKSISQQSDMVRFLFYRRNTGVDISTLESASFRNWFISTDMQQDYTKPVDMCQKAAPNRLTTFTIQRHN