Protein
Probable deoxyuridine 5'-triphosphate nucleotidohydrolase
Organism
Invertebrate iridescent virus 6
Function
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
Similarity
Belongs to the dUTPase family.
Sequence
MDKKPTIAILKNEIDKLKSSFDTEKDEKDTKINHILSVVEGLSKSLSLYIEDNDKETTNEEVNIDEIDKNIVKNLEDKVNCLEQDVQYLKNELKKKDADWQQKLDLIVHQFTKQYDSLKSSLLISQKETSVFQSVQNNSNLPNNSNLPIETPILQIKFAALTEYAQKPKRGSEFSAGIDLRSAYEYLVPANGNKLIKTDWKIQYPDGYFGKICSRSGLSLNHNLEVGAGIVDADYREGVSVVLNNLSPRDFHVAPGDRIAQLVCTPYITPEIVFCKPSDIPDTVRGKNGFGSTGIN