Protein
Probable DNA-directed RNA polymerase II subunit RPB2 homolog
Organism
Invertebrate iridescent virus 3
Function
Component of the DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit (By similarity).
Similarity
Belongs to the RNA polymerase beta chain family.
Sequence
MNQLNQKTKLDKHLSSDNRAKIVADYFKTNGLVKHQIETFNHFISKGLKTIINNESSIKYQSHDNYSLKFTNIYVEYPSIIDDDRTIRDLYPQEARNKDLSYTGNVCVNVIEMVENKEGKPPQISEQYRVPIAKIPIMLGSDVCHLSKYTPLENEQINGHSQADQGGYFIINGKERVLISQVRKAYNKPVCFVKSTSQKEDVLICEMRSMCEETFHSTSVQVKMIKNKIMVSLKLKRKLIDIPVGIVFKCLGYNPDQMGSKFRSLFNLPPEYEKYIDAIKNDCLEEFAYGIAVSAADGDNSDSGGESGGEEEADQEEHIVKVFRNMSTSVDKDGGMAATGITIEDVQKSLDMDLFPHLGITSTRKQRVDLLAFMVKKYLLTLTRKIPVDNRDDYNHKRVETAGELYSFLFRLLYKKFQKTCITQIRNRKPDISNFLRTSGITTGILYSFSSGYWGVQRNTYIRTGVSQVVNPKVSLLANYSSLRRVVIPESKDGKEAKTSEIRQIHPSSSFLVCPVETPEGKGVGTVLNMAVFCQVTTGISTCEIMDQIDSFGVDLKCHCTIKDPNNCLLLLINGSPYGNGHANVIHRLNFLNDTNISIVVNRALGVIEIFSDAGRFIRPIFDLDKICNFEGEIVPSFKWFLDNQLIRYIDINEAAANSIAIELRDLSTNPNTRYNLMELDPCGMFGIVAGIIPFPDRTQSARNCFYSSMVKQAIGFVPCHNLKTETVSHTLNYPQKPLVTTSFAEYNQLNEYPNGINAIVAIACYTGYNQEDSIILNKSSIDRGLFGTITYNTFTAQEKKNGIIEERIEIPSNAIKIRDCNYGLVGPDGIVRLRQRVKKGDVLICKVTIKNKNQDEKLVDSSVIVQHGEEGYVDRIVDNVIDGCRIVKVVIGQMRTPEIGDKFCSGMAQKGTCGMIFPQEDMPFTASGMTPDIIINPNCIPSRMTINQIISTVMGKLYTVNPNPRFRNGNSFQENSNTILKELCHHLKLNGFDPSGSEVMYSGFTGERIQSTIFMGPTYYHRLKHMVKDKMHARSHGQVTTLHRQPNCGRSQGGGLRFGEMEKDCILVHGATQFLNERMFLNSDPFQIDVCKDCGMMSSTSKKCHHCGSINVKRCNIPYSCKNLLQELNGMGIKTKIDL