About Products Protein Database Contact

IGFBP2

Gene
IGFBP2
Protein
Insulin-like growth factor-binding protein 2
Organism
Homo sapiens
Length
325 amino acids
Function
Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Mass
34.814 kDa
Sequence
MLPRVGCPALPLPPPPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEKRRDAEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKPLKSGMKELAVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECHLFYNEQQEARGVHTQRMQ

Gene
IGFBP2
Protein
Insulin-like growth factor-binding protein 2
Organism
Bos taurus
Length
317 amino acids
Function
Inhibits IGF-mediated growth and developmental rates (By similarity). IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Mass
34.015 kDa
Sequence
MQPRLGGPALLLLPPLLLLLLLGAGGGDCGARAEVLFRCPPCTPESLAACKPPPGAAAGPAGDARVPCELVREPGCGCCSVCARLEGERCGVYTPRCGQGLRCYPNPGSELPLRALVHGEGTCEKHGDAEYSASPEQVADNGEEHSEGGLVENHVDGNVNLMGGGGGAGRKPLKSGMKELAVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECHLFYNEQQGARGVHTQRMQ

Gene
IGFBP2
Protein
Insulin-like growth factor-binding protein 2
Organism
Ovis aries
Length
317 amino acids
Function
Inhibits IGF-mediated growth and developmental rates (By similarity). IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Mass
34.189 kDa
Sequence
MQPRLGGPALLLLPPLLLLLLLGAGGGDCGARAEVLFRCPPCTPESLAACKPPPGAAAGPAGDARVPCELVREPGCGCCSVCARLEGERCGVYTPRCGQGLRCYPNPGSELPLRALVHGEGTCEKHGDAEYSASPEQVADNGEEHSEGGQVENHVDGNVNLMGGGGGAGRKPLKFRMKELAVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECHLFYNEQQGARGVHTQRMQ

Gene
IGFBP2
Protein
Insulin-like growth factor-binding protein 2
Organism
Sus scrofa
Length
316 amino acids
Function
May have both growth-inhibiting and growth-promoting effects, depending on tissue type; increases IGF-induced DNA synthesis in the uterine epithelium. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Mass
33.937 kDa
Sequence
MLPRLGGTALSLLPLLLLLLGTGGRGARAEVLFRCPPCTPESLAACRPPPAAPPSAGAGPAGDSRAPCELVREPGCGCCSVCARLEGERCGVYTPRCAQGLRCYPHPGSELPLQALVLGEGTCEKRRDAEYGASPEQVADNGDDAEGGLVENHVDGNVNLLGGTGGAGRKPLKSGMKELAVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECHLFYNEQQGARGAHTQRMQ

Gene
IGFBP2
Protein
Insulin-like growth factor-binding protein 2
Organism
Gallus gallus
Length
311 amino acids
Function
Inhibits IGF-mediated growth and developmental rates (By similarity). IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Mass
33.538 kDa
Sequence
MALGGVGRGGAARAAWPRLLLAALAPALALAGPALPEVLFRCPPCTAERLAACSPAARPPCPELVREPGCGCCPVCARLEDEACGVYTPRCAAGLRCYPDPGAELPPQALVQGQGTCARPPDTDEYGASTEPPADNGDDRSESILAENHVDSTGGMMSGASSRKPLKTGMKEMPVMREKVNEQQRQMGKVGKAHHNHEDSKKSRMPTGRTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSVNGQRGECWCVDPIHGKVIQGAPTIRGDPECHLFYTAHEQEDRGAHALRSQ

Gene
Igfbp2
Protein
Insulin-like growth factor-binding protein 2
Organism
Mus musculus
Length
305 amino acids
Function
Inhibits IGF-mediated growth and developmental rates (By similarity). IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Mass
32.847 kDa
Sequence
MLPRLGGPALPLLLPSLLLLLLLGAGGCGPGVRAEVLFRCPPCTPERLAACGPPPDAPCAELVREPGCGCCSVCARQEGEACGVYIPRCAQTLRCYPNPGSELPLKALVTGAGTCEKRRVGTTPQQVADSDDDHSEGGLVENHVDGTMNMLGGGSSAGRKPLKSGMKELAVFREKVNEQHRQMGKGAKHLSLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDDRGPLEHLYSLHIPNCDKHGRYNLKQCKMSLNGQRGECWCVNPNTGKPIQGAPTIRGDPECHLFYNEQQETGGAHAQSVQ

Gene
Igfbp2
Protein
Insulin-like growth factor-binding protein 2
Organism
Rattus norvegicus
Length
304 amino acids
Function
Inhibits IGF-mediated growth and developmental rates (By similarity). IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Mass
32.855 kDa
Sequence
MLPRLGGPALPLLLPSLLLLLLLGAGGCGPGVRAEVLFRCPPCTPERLAACGPPPDAPCAELVREPGCGCCSVCARQEGEACGVYIPRCAQTLRCYPNPGSELPLKALVTGAGTCEKRRVGATPQQVADSEDDHSEGGLVENHVDGTMNMLGGSSAGRKPPKSGMKELAVFREKVNEQHRQMGKGAKHLSLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDDRGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKPIQGAPTIRGDPECHLFYNEQQENDGAHAQRVQ

Gene
igfbp2
Protein
Insulin-like growth factor-binding protein 2
Organism
Xenopus tropicalis
Length
284 amino acids
Function
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors (By similarity).
Mass
30.891 kDa
Sequence
MGLSRYLLGLLLGVLCTPAPAEVLFRCPPCSPERLATCPGSAPRPPCAELVRAPGCGCCPVCARLEGESCGVYTARCAGGLRCYPHPGSELPLQALVLGLGTCGKRRDTEYGSSQERGTELPEERSDNMLVDNKLEAGPAVAGEAAPRKPSKKEMKEIAVTRERANEQQRSKSNKSEDKKRPARSLCQLQLDQVLERISGMHLPDDRGPLEHLYALHIPNCDKNGFFNLKQCKMSVNGQRGECWCVNPITGKALPGSPTIRGDPECHLYYTSPEEGRAHTQRAP

Gene
igfbp2
Protein
Insulin-like growth factor-binding protein 2
Organism
Xenopus laevis
Length
281 amino acids
Function
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors (By similarity).
Mass
30.592 kDa
Sequence
MVLSEHLLVLLGAVLCAPALSDVLFRCPPCSPERLAACPGNSPRSPCAELVRAPGCGCCPVCARLEGESCGVYTARCAGGLRCYPHPGSELPLQALVLGLGTCGKRRDAEYGSSQERGTELPEDQSDNMLVDNNLVAGPAVPGDFMPRKSSKAHAVNRERANEQHRSKTNKSEDKKRPARSLCQLQLDQVLERISGMHLPDDRGPLEHLYALPIPNCDKNGFFNLKQCKMSVNGQRGECWCVNPITGKVLPGSPTVRGDPECHLFYTNPEEERRAHTQRAP

Gene
igfbp2
Protein
Insulin-like growth factor-binding protein 2
Organism
Oncorhynchus tshawytscha
Length
20 amino acids
Function
Inhibits IGF-mediated growth and developmental rates (By similarity). IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Mass
2.287 kDa
Fragment
single
Sequence
DLVFYCPKCTAERQTACPKL