henmt1

Small RNA 2'-O-methyltransferase

402 amino acids

Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation and adenylation activities and subsequent degradation. Stabilization of piRNAs is essential for oocyte development.

Belongs to the methyltransferase superfamily. HEN1 family.

46.124 kDa

MTATPFSPPLYMQRYQFVIDYVKTYRPRKVIDFGCAECCLLKKLKFHRNGIQLLVGVDINSVVLLKRMHSLAPLVSDYLQPSDGPLTIELYQGSVMEREPCTKGFDLVTCVELIEHLELEEVERFSEVVFGYMAPGAVIVTTPNAEFNPLLPGLRGFRNYDHKFEWTRAEFQTWAHRVCREHGYSVQFTGVGEAAGHWRDVGFCTQIAVFQRNFDGVNRSMSNAEHLEPSVYRLLYRVVYPSLCDNNIYQKTLINEVLYEAQHLRQQWLIRENMNNNAHFYSPPLMEALHHGAEGNACEQQPVYQQGGIICVPLARVWSCPRVQALCGSLQRLREKLLEDERVRMSADGSALNLPADDDDDNVEEEEEEEEEENQQNVKAVSGAVNNMEEDWDRELGSYGDE

Henmt1

Small RNA 2'-O-methyltransferase

395 amino acids

Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.

Belongs to the methyltransferase superfamily. HEN1 family.

44.921 kDa

MEMAESIPCNSVVGGNFKEVSPEKVIRFKPPLYKQRYQFVRDLVDRHEPKKVADLGCGDAKLLKLLKIYPCIQLLVGVDINEEKLHSNGHRLSPYLGEFVKPRDLDLTVTLYHGSVVERDSRLLGFDLITCIELIEHLDSDDLARFPDVVFGYLSPAMVVISTPNAEFNPLFPTVTLRDADHKFEWSRMEFQTWALHVANCYNYRVEFTGVGTPPAGSEHVGYCTQIGVFTKNGGKLSKPSVSQQCDQHVYKPVYTTSYPSLQQEKVLKFVLVGELLIQVDRLRLRYQRMLRDREKDRGPKPGDMDSCPAPHLLLGAVFTEAEKARIESSPKPFCEGEKFYIPLQRLLTYPKLHRLCADEDRVRSLIADSVCLSSDGSAVVVDLHNSWDYRPEEN

Henmt1

Small RNA 2'-O-methyltransferase

394 amino acids

Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.

Belongs to the methyltransferase superfamily. HEN1 family.

45.087 kDa

METAENIPCSMLGDNFKEVCAEKVIRFRPPLYKQRYQFVRDLVDRHEPKKVADLGCGDTKLLKLLKIYPCIQLLVGVDINEEKLHSNGHRLSPYLGEFVKPRDLDLTVTLYHGSVVERDSRLLGFDLITCIELIEHLDSDDLARFPEVVFGYLSPAMVVISTPNAEFNPLFPTVTLRDADHKFEWSRMEFQTWASQVANCYNYCVEFTGVGTPPAGSEHVGYCTQIGVFRKNGGKLSEPSASQQRDQHVYKAVYTTSYPSLQQEKVLKFVLVGELLIQVDRLRLRHQRMLREQEKERGPKPWYTDSSPAPHLLLGAVFTEAEKARIENSPKPFCEGEKFYIPLQRLLTYPKLHRLCADEDRMRSLIADSVCLSSDGSAVVVDLHNSWDYRPEDN

HENMT1

Small RNA 2'-O-methyltransferase

393 amino acids

Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.

Belongs to the methyltransferase superfamily. HEN1 family.

44.525 kDa

MEENNLQCSSVVDGNFEEVPRETAIQFKPPLYRQRYQFVKNLVDQHEPKKVADLGCGDTSLLRLLKVNPCIELLVGVDINEDKLRWRGDSLAPFLGDFLKPRDLNLTITLYHGSVVERDSRLLGFDLITCIELIEHLDSGDLARFPEVVFGYLSPSMIVISTPNSEFNPLFPSVTLRDSDHKFEWTRMEFQTWALYVANRYDYSVEFTGVGEPPAGAENVGYCTQIGIFRKNGGKATESCLSEQHDQHVYKAVFTTSYPSLQQERFFKLVLVNEVSQQVESLRVSHLPRRKEQAGERGDKPKDIGGSKAPVPCFGPVFTEVEKAKIENSPTPFCVGDKFFVPLQRLLAYPKLNRLCANEEMMRSVIADSIPLSSDGSAVVADLRNYFDEQFEF

HENMT1

Small RNA 2'-O-methyltransferase

393 amino acids

Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.

Belongs to the methyltransferase superfamily. HEN1 family.

44.573 kDa

MEENNLQCSSVVDGNFEEVPRETAIQFKPPLYRQRYQFVKNLVDQHEPKKVADLGCGDTSLLRLLKVNPCIELLVGVDINEDKLRWRGDSLAPFMGDFLKPRDLNLTIILYHGSVVERDSRLLGFDLITCIELIEHLDSGDLARFPEVVFGYLSPSMIVISTPNSEFNPLFPSVTLRDSDHKFEWTRMEFQTWALYVANRYDYSVEFTGVGEPPAGAENVGYCTQIGIFQKNGGRATEACVSEQHDQHVYKAVFTTSYPSLQQERFFKLVLVNEVSQQVESLRVSHLPRRKEQDGEQGDKPKDIGGSKAPVPCFGPVFTEVEKAKIENSPKPFCVGDKFFVPLQRLLAYPRLNRLCANEEMMRSVIADSIPLSSDGSAVVTDLCNYFDEQFEF

HENMT1

Small RNA 2'-O-methyltransferase

376 amino acids

Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.

Belongs to the methyltransferase superfamily. HEN1 family.

43.007 kDa

MDKNFEGKQFTGVIKFTPPLYKQRYEFVQDLVRKYEPKKVADLGCADCTLLWMLKFCSCIEVLAGLDICETVMKEKMHRLTPLPADYLEPSERSLIVTLHQGSVAHKDPCMLGFDLVTCIELIEHLQESELEKFPEVVFGFMAPNMVVISTPNSEFNTLLPGVTVFRHPDHKFEWDRAQFQSWAQDTAERYEYSVEFTGVGSPPTGMEDVGFCTQIGVFVKKYPQTREPVQREKPTEAAYKTVFKAVYPSLKDEKYLQNAVVSEVMFRAQLIKRSLLDHLLSECEEYNDDPTERKLKLQCSVNCFSEDVETLAVEKSTEPFVSGNVIYIPLRKIFSVPKVNQLCGTFEKFCRLITGKVTLNSDSSALMLDTENEEN

henmt1

Small RNA 2'-O-methyltransferase

369 amino acids

Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.

Belongs to the methyltransferase superfamily. HEN1 family.

42.977 kDa

MELEFFKPPLYQQRYQFVKSYVDTYKPKKVADLGCSTCSLLHTLRFWDCIKVLVGLDIDEDVLSRKKFTLTPLPAHYLEPRNTSLTINLYQGSVTQKDPALLGFDLITCIELIEHLEAEELENFREVLFGFMAPITVIISTPNAEFNILFPKCTGFRHPDHKFEWNRREFQSWATEVAKCFNYTVEITGVGEPPRDSKNVGFCSQIAVFTRNYTESEESLQRKMECKSVYKTVLHIVYPSLQEEKYLRRAVQKVALFHAYQIKANFLQQFIHREEEEEPHNTDTEHRPCMDLKLTSRWPTLPQTEQDESMEPFLQEDTLYVPLKKIFSVPKVKELCGNMDNLRTMITGEATLSNDGNAILYHIDLENSC