HSD3B2

3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2

373 amino acids

The 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. Also able to act as 3-keto-reductase reducing 5-alpha-dihydrotestosterone to the corresponding 3-beta-androstan-3-beta,17-beta-diol.

Belongs to the 3-beta-HSD family.

41.903 kDa

MPGWSCLVTGAGGFLGQRIIHLLVQEKDLEEVRLLDKVFRPETREEFFKLQTKTKVTVLEGDILDAQCLRRACQGISVVIHTAAAIDVWGIIPRQTIIDINVKGTLNLLEACVQASVPAFIYTSSIDVAGPNSYKEIVLNGHEEQQHESTWSDPYPYSKMMAEKAVLAANGSFLKNGGTLHTCALRPMYIYGEKSSILSGIMIRAIKNNGILKVTGKFSTVNPVYVSNAAWAHILAARGLQDPKKSPNIQGQFYYISDDTPHQSYDDLNNTLSKKWGLRPDSSWRPPVALLYWLGFLLELVNFLLRPVYNYQPPFTRYLVTISNTVFTFSYKKAQRDLGYEPLVGWEEARENTSEWIGSLVEQHKGTLNTKAQ

Hsd3b2

3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2

373 amino acids

3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.

Belongs to the 3-beta-HSD family.

41.923 kDa

MPGWSCLVTGAGGFLGQRIIQLLVQEEDLEEIRVLDKVFRPETRKEFFNLETSIKVTVLEGDILDTQYLRRACQGISVVIHTAAIIDVTGVIPRQTILDVNLKGTQNLLEACIQASVPAFIFSSSVDVAGPNSYKEIVLNGHEEECHESTWSDPYPYSKKMAEKAVLAANGSMLKNGGTLQTCALRPMCIYGERSPLISNIIIMALKHKGILRSFGKFNTANPVYVGNVAWAHILAARGLRDPKKSPNIQGEFYYISDDTPHQSFDDISYTLSKEWGFCLDSSWSLPVPLLYWLAFLLETVSFLLSPIYRYIPPFNRHLVTLSGSTFTFSYKKAQRDLGYEPLVSWEEAKQKTSEWIGTLVEQHRETLDTKSQ

HSD3B2

3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2

372 amino acids

3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.

Belongs to the 3-beta-HSD family.

42.052 kDa

MGWSCLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEGDILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTLYTCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRALRDPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRWSLPLTLMYWIGFLLEVVSFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLVDRHKETLKSKTQ