HOT1

Gene

HOT1

Protein

High-osmolarity-induced transcription protein 1

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

719 amino acids

Function

Required for a complete transcriptional response to osmotic stress, through recruitment of HOG1 followed by pol II recruitment to the promoters of GPD1 and other HOG-dependent genes.

Similarity

Belongs to the HOT1 family.

Mass

79.416 kDa

Sequence

MSGMGIAILCIVRTKIYRITISFDYSTLMSPFFLFLMMPTTLKDGYRMNSQVNEDAIGINLDLSLPTHISPTTGSESASGSNASTLRNDGNALDGGLLRTSAAISAPTGTSQPTETIGEKLSNEERVNSNVSASNSTTAGTGRMLSQSLTNDSPSNEISTDQLKIFQRMDEMSARMIEMEESFNKLSNKIAEQNTMVLNLKQDNYKVMNKLNILLKLVAQPSARPSTNNAQNKLAIELLNSISAVSSAYLQKMQNNGSGRQHTADLCTGDSNTHSGINQHRTTNGTIDVNTNTAQLNNQFSNALNTILPDQQHNRNNVSQNINQSLPNRQLGPVINTQANQNQSQVLIHNTNTHQQVNRSPISFPNASTDKPFKLNPNGIKRRRRNTQSNNNASTNDHASAAQKPISALSPLTNSHNSTTSMNYTNSSIHSGVTSASNSFHDLNSLNNFGTTTALSLPSLALDNASFPPNQNVIPPIINNTQQPLSFSQLINQDSTTSELLPSGKSGVNTNIVNRNRASTLPSYPKPMTVKSNVDDDGYQEDDDDDGDDEGDGRDNEEDSTAEEDEVDDEIETDMKNASINKRRRSLHHKKSNSLNGRRKLHGESATKPNINSDLHYRILKAPTDVKTIWEEYDTGIRGKPSIKHLEAKYGNKWRLNKNKKTFSRRKRLYKFILNGMERGKTAQEMIETLENKRLYKDDEDGEVKKRTIGWLQESLAGI

Protein

High-osmolarity-induced transcription protein 1: HOT1

Gene

HOT1

Protein

High-osmolarity-induced transcription protein 1

Organism

Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)

Length

679 amino acids

Function

Required for a complete transcriptional response to osmotic stress.

Similarity

Belongs to the HOT1 family.

Mass

73.929 kDa

Sequence

MSAMENRKNSLHGSPNGLSGLNMVLPREGDSNNGIMTTEDARNGKLKGDKDLNMKMHVGMGTTPINTRLGNTMNSDVANSMSYLLEQPQSGTLIGDRLILETSEEPVGVNLVDGQNARNNQQMLNNASHMDPAFTLPADDTMNNSAAAAAAAAAAAAASTGPSQPTMQSTPSISTGGSTNFQVQIAQRLADIDQRILRMEMLMDNVCNKIDSHSQQQSLWKNDMHQMENKVIDVLDEIKSNIFSLKRQVSNQGDGAFAAELINAISNVSNKHIRKNTYGFPAGNPQGNDMGQTMNGYNNAMQLSSMAAPMSYVPGEQVNLNQLGNSKDQIDRFLTKSANEFMLDPSGLKKRRKNPSSSNESPITLSHTKTHSTSQPINYSASLPNLNLDALSKVMLPQHQQLTHNGGSQHPLSDKSIKFGISSTSHSSSNSSDSDDEEDDIDDEEDEAEDEEDENDDSRDVNDHDNVEGRETLTKKSMKPGNSIEGRDPSGTNGTVNSTTNNHMNTIDTATNTSSQLQGTVIRSTADTENPKQESNASAAATSGAATGVATGTTTANIATSASDKLKLHGDSKKEPKFTMIKAPSSVKEIWREYTQGIDGRPSIKSLDQKFGNKWRANKNKKTYSRRKRMYKFILNGIKKGKSEEEMVQMLENKRIYKDSDGNQKKRTIGWLQQSLSGI

Protein

High-osmolarity-induced transcription protein 1: HOT1

Gene

HOT1

Protein

High-osmolarity-induced transcription protein 1

Organism

Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)

Length

658 amino acids

Function

Required for a complete transcriptional response to osmotic stress.

Similarity

Belongs to the HOT1 family.

Mass

73.097 kDa

Sequence

MSDAGDSKLAKEQSDASTGTCNGNGTGNGTGSGTATANATTTPTPTPTSIPTAAGSVTDVTATSSMVLAKLDDISSRLTMLESNFNNVFSKINDQNSMILDLKQNNSHAFLRLSSKVNKLETHVAALASNNPQSAFVTDLLNSITNVSSSYLRKMKHNGAENLNVQLSTHENGFVHPTPNDSPNMMGPIYYNQIETSKARGQLKSLNRKKTFTLNPNGIKKRRLGHHHGNSGSRSNNLNVTFDITGQVGQPGYDTSLNSATPNNHAMTPSNVISSSNSYSELQSLNGLQSNTTASDGRTLSPVNTVQALKTPYLTATNQHSLNHGSLNNYNLNFPQFLDNTNSVTLSRLGSSSPVEKRDGIVMSHSAPQLDNGSITYPDNRLHIRNQASQDILGGASQGQPQKINNIDEDGYQEDDEEEESELNKHKNKVGNLKYNTTLTDSHSINDDRKPTVNVYASTGHPVNNTKSEYLEDDESNDSDNSHETDEESEDEVEEYDEEDDMVNEEDRQPYSRKPKEPASERKRKKLRKINKYRNNVIEPRKKDDKEKDAQNSDLNYMLLKAPSSVKTIWEEYVNGIDGNPSIRGLEEKYGNKWRIKRNKKTFSRRKRLYKFILNGIDKGKTADEMIDMLEKQRLYRDENGEIKRRTIGWLQQSLIGI

Protein

High-osmolarity-induced transcription protein 1: HOT1

Gene

HOT1

Protein

High-osmolarity-induced transcription protein 1

Organism

Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)

Length

629 amino acids

Function

Required for a complete transcriptional response to osmotic stress.

Similarity

Belongs to the HOT1 family.

Mass

69.019 kDa

Sequence

MIDPVTHIVTPSNDEQRQGRSDGGMQLGLEDLHGGGGGLGQQKVSGMAEGTDSIVDVLTNPSSSVNLHSNILSVSTNVEEGQGMQPAAIQGGGTAAGRRFSSVPISDSPVGCGQHGMGTASTQVPSHGSTANLLSMGNPVATNVQVCQRMDEVSARLIVMEETVNKLLGNIDAQQQQIASMRSESMEMLGSLMKEVRELKQQVPVLDDPDNNEKDKFVTDLLNSITNVSSNYLKKVSSRNLQRFKRQRDIMSTSDLPSLGNTQSSSHFMQDLVNPYASTQDFQSFTVLKDKAKEFTLNPTAINKRRRLSAQPLNTLQMSQDQLQQQRGSVQSLISIPTSGQKNANFGPQLQNYLIGLQNIPMSEAEKVSSPTVLKQFQNSTTDPDLKTGRRNPGLDFQIGSGDDENDENDGASGEDEDGYLEDDEGYRSQSQRTMSSEDDEQFTGGNQGEDEAGPRAAGRNPKSLPSSIVRRFANSGSQVSVSGTPETERLVLKNNDKYDKNTMPAPNTKPRAVLASNPEDTLTDVQYTMVKAPDSVRAIWDEYTIGVGGKPSIRQLEQTYGNKWRTKRNKKTFARRKRIYKFILNGVRNGKSESEMIDILESRRVYRTEDNELKKRTIGWLQQSLSGI

Protein

High-osmolarity-induced transcription protein 1: HOT1