Protein
Homologous-pairing protein 2
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Function
Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Stimulates DMC1-dependent homologous strand assimilation required for the resolution of meiotic double-strand breaks.
Similarity
Belongs to the HOP2 family.
Sequence
MAPKKKSNDRAIQAKGSEAEQLIEDYLVSQYKPFSVNDIVQNLHNKVTKTTATKALENLVNEKRIVSKTFGKIIIYSCNEQDTALPSNIDPSQFDFETVLQLRNDLIELERDKSTAKDALDSVTKEPENEDLLTIIENEENELKKIESKLQSLQDDWDPANDEIVKRIMSEDTLLQKEITKRSKICKNLIATIKDSVCPKNMNEFLEEIGFEDI