Protein
Mating-type protein ALPHA3
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Function
Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion. Required for efficient mating as an alpha-cell.
Sequence
MAQVDVTRWVIHPSGSYESETRKRKLREEKRRKLNEIKRASLVLNDSDFKNFEHWLVTSKGVGEYEQVFDFNFDAYTTRGKPAVDSSTSYSDNIFIDGDKNCKIDTKTISFLDRKYQSNNQTKIESEKQMHVITLKNEQLIEECKNIRERLLELIREGTGYIFVRGWTGYRVNTIILKCHCKQDKCHQILKPRCNVKKHHDPDNLKQFNCFSSFSVHFNVKLNTIKICFCHKSKHETLPITIIPASLRQYISTNLCFTARECFECLKRTPVYLEFTKSFDAKAIVRKIWKEISESQWNLDPDSKRSASKILKRFQNTGDVALLPVDNCSADLNISLQKAKPIAFIYERIISEIQHDVTEIVIDSTFCLSTDYKQYFVVVASFFGKGVPVGFMATETNNVDHLTILWFLRSVLQKLPKVKCINSDWSLAEIKAINLLKCSNQICLFHTLTAIRCKRLASKKNMTESLFHQQFQSLLNYEWVDDNIFDPTRYEEKYQEKVSEYQIREIVRLVRIAICDHILLHSAGLNKVFQDSDSENVKVLKLYEYHLKQLYVITVQKFSLPCYFCYLFNQYYNFTSFQIMSRVGKPTFFSVLRTSMMCESYFNQLKSWNLSGSRNYRFDTLIYILLNKEVAKIKESIRITKKFEKEYDSNCLVQNHRKHLPTWRKQWIIEWKNILQELNCLQEKDVFNECQQYGTNMTTWICGCNDAKVSPSSTCIHLVSLYKQKFPFYHGYTLQRFGKRNNGVPLVQHESLQSDTKIESTENMSFEISDVTINGVCNTTKQMSDANCRKLDYETEIDMISENKHSEIDDESEGKLRIFNFFLADEETRLLITQCPSFKSIIEEMTYIKQRTQSEPQWKAKTNKPEKGFKYDSWIRCLKYYQCYADVKANGNFPLPF