HJV

Gene

HJV

Protein

Hemojuvelin

Organism

Homo sapiens

Length

426 amino acids

Function

Acts as a bone morphogenetic protein (BMP) coreceptor. Through enhancement of BMP signaling regulates hepcidin (HAMP) expression and regulates iron homeostasis.

Similarity

Belongs to the repulsive guidance molecule (RGM) family.

Mass

45.08 kDa

Sequence

MGEPGQSPSPRSSHGSPPTLSTLTLLLLLCGHAHSQCKILRCNAEYVSSTLSLRGGGSSGALRGGGGGGRGGGVGSGGLCRALRSYALCTRRTARTCRGDLAFHSAVHGIEDLMIQHNCSRQGPTAPPPPRGPALPGAGSGLPAPDPCDYEGRFSRLHGRPPGFLHCASFGDPHVRSFHHHFHTCRVQGAWPLLDNDFLFVQATSSPMALGANATATRKLTIIFKNMQECIDQKVYQAEVDNLPVAFEDGSINGGDRPGGSSLSIQTANPGNHVEIQAAYIGTTIIIRQTAGQLSFSIKVAEDVAMAFSAEQDLQLCVGGCPPSQRLSRSERNRRGAITIDTARRLCKEGLPVEDAYFHSCVFDVLISGDPNFTVAAQAALEDARAFLPDLEKLHLFPSDAGVPLSSATLLAPLLSGLFVLWLCIQ

Protein

Hemojuvelin: HJV

Gene

Hjv

Protein

Hemojuvelin

Organism

Rattus norvegicus

Length

422 amino acids

Function

Acts as a bone morphogenetic protein (BMP) coreceptor. Through enhancement of BMP signaling regulates hepcidin (HAMP) expression and regulates iron homeostasis.

Similarity

Belongs to the repulsive guidance molecule (RGM) family.

Mass

45.221 kDa

Sequence

MGDRGRSPSLRSPHGSPPTLSTLTLLLLLCGQAHSQCKILRCNAEYVSFTLSLRGGGSPDTPRGGGRGGPASGGLCRALRSYALCTRRTARTCRGDLAFHSAVHGIEDLMIQHNCSRQGPTASPPARGPALPGAGPAPLTPDPCDYEARFSRLHGRTPGFLHCASFGDPHVRSFHNHFHTCRVQGAWPLLDNDFLFVQATSSPVASGANATTIRKITIIFKNMQECIDQKVYQAEVDNLPAAFEDGSVNGGDRPGGSSLSIQTANLGSHVEIRAAYIGTTIIVRQTAGQLSFSIRVAEDVARAFSAEQDLQLCVGGCPPSQRLSRSERNRRGAIAIDTARRLCKEGLPVEDAYFQSCVFDVSVSGDPNFTVAAQSALDDARVFLTDLENLHLFPVDAGPPLSPATCLVRLLSVLFVLWFCIQ

Protein

Hemojuvelin: Hjv

Gene

Hjv

Protein

Hemojuvelin

Organism

Mus musculus

Length

420 amino acids

Function

Acts as a bone morphogenetic protein (BMP) coreceptor. Through enhancement of BMP signaling regulates hepcidin (HAMP) expression and regulates iron homeostasis.

Similarity

Belongs to the repulsive guidance molecule (RGM) family.

Mass

44.848 kDa

Sequence

MGQSPSPRSPHGSPPTLSTLTLLLLLCGQAHSQCKILRCNAEYVSSTLSLRGGGSPDTPRGGGRGGLASGGLCRALRSYALCTRRTARTCRGDLAFHSAVHGIEDLMIQHNCSRQGPTAPPPARGPALPGAGPAPLTPDPCDYEARFSRLHGRAPGFLHCASFGDPHVRSFHNQFHTCRVQGAWPLLDNDFLFVQATSSPVSSGANATTIRKITIIFKNMQECIDQKVYQAEVDNLPAAFEDGSINGGDRPGGSSLSIQTANLGSHVEIRAAYIGTTIIIRQTAGQLSFSIRVAEDVARAFSAEQDLQLCVGGCPPSQRLSRSERNRRGAIAIDTARRLCKEGLPVEDAYFQSCVFDVSVSGDPNFTVAAQTALDDARIFLTDLENLHLFPSDAGPPLSPAICLVPLLSALFVLWLCFSK

Protein

Hemojuvelin: Hjv