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HCBG_01775

Gene
HCBG_01775
Protein
ATP-dependent (S)-NAD(P)H-hydrate dehydratase
Organism
Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)
Length
368 amino acids
Function
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
Similarity
Belongs to the NnrD/CARKD family.
Mass
39.605 kDa
Sequence
MSSPSKKLLANVRRIVPPMLERFHKGQLGRVAVIGGSAECAPHISLQWHLQGLSHVICEPSSATVIKSYSPNLMVHPILQSSNTVSSFSNSPLPHPHARALAEPVLSFLSRLHVLVIGPGLGRDPVTQEIVTEIIKEARSREIPLVLDADALLLVQEHPDLIHGYTECILTPNVVEFARLAKALRADVSSMPDSDAGKSEACKRLSNALGGVTIIQKGPHDTISNGMVNIVCDVRGGLKRSGGQGDTLTGSLGTLLAWRKAYHEGLWDTGESEASGGRELSRQDIEEDLSICGYESGDDGERDGDKPKKKLSRPATLLLVAWAGSAITRECSRRAFMAKGRSMQASDLTDEVHGSFLDLIGEPEGTKL