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HAP3

Gene
HAP3
Protein
Transcriptional activator HAP3
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
205 amino acids
Function
Binds to the upstream activation site (UAS) of the CYC1 gene and other genes involved in mitochondrial electron transport and activates their expression. Recognizes the sequence CCAAT.
Similarity
Belongs to the NFYB/HAP3 subunit family.
Mass
23.123 kDa
Sequence
MDTETEAEKQERHNNYLNELAEQDRWLPINNVARLMKNTLPATTKVSKDAKECMQECVSEFISFVTSEACDRCTSGKRKTINGEDILLSLHALGFENYAEVLKIYLAKYRQQQAIKNQMMYPKEDVEGSYTEEESRAEDADHVTQERQQPLHPVPSSASTTTSTEVSASEHVQSSSKSTHNPAQAQPRIVVQQPLGSRHSTADHL

Gene
HAP3
Protein
Transcriptional activator HAP3
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
144 amino acids
Function
Acts a component of the CCAT-binding factor, which is a transcriptional activator and binds to the upstream activation site (UAS2) of the CYC1 gene and other genes involved in mitochondrial electron transport and activates their expression. Recognizes the sequence 5'-CCAAT-3'.
Similarity
Belongs to the NFYB/HAP3 subunit family.
Mass
16.154 kDa
Sequence
MNTNESEHVSTSPEDTQENGGNASSSGSLQQISTLREQDRWLPINNVARLMKNTLPPSAKVSKDAKECMQECVSELISFVTSEASDRCAADKRKTINGEDILISLHALGFENYAEVLKIYLAKYRQQQALKNQLMYEQDDEEVP

Gene
hap3
Protein
Transcriptional activator hap3
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
116 amino acids
Function
Belongs to a complex that binds to the sequence CCAAT located upstream of genes involved in mitochondrial electron transport.
Similarity
Belongs to the NFYB/HAP3 subunit family.
Mass
12.91 kDa
Sequence
MSADGLDYTNLLPIANVARIMKSALPENAKISKEAKDCVQDCVSEFISFVTGEASEQCTQEKRKTITGEDVLLALNTLGFENYAEVLKISLTKYREQQARSASMKETKQSRSEEPQ