Protein
Probable GDP-L-fucose synthase
Organism
Drosophila melanogaster
Function
Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
Similarity
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
Sequence
MKKVLVTGGTGLVGKALEAVIKEQSPEDEQWFFAGSKDADLTNLAATQALFAREKPTHVIHLAAMVGGLFHNMNNNLDFLRNNLLINDNVLQTAHEQGCVKVVSCLSTCIFPDKTSYPIDETMVHNGPPHPSNYGYSYAKRLIDVQNHAYHDKYGRVYTSVIPCNIFGPHDNYNPEVSHVIPGMIYRMHQLVTEKTDVPENDKVFTVFGSGMPLRQFVYSRDLAELMIWVLRNYESVEPIILSADEVQEVTIFEVAQAVAKAFNFNGRLVCDTSKSDGQYKKTASNAKLRSFLPDYAFTDLETAINASVKWYIENYDQARK