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GRPEL1

Gene
GRPEL1
Protein
GrpE protein homolog 1, mitochondrial
Organism
Bos taurus
Length
217 amino acids
Function
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity).
Similarity
Belongs to the GrpE family.
Mass
24.306 kDa
Sequence
MAARCVRLARGSLPAFALSLRSSPRLLCTAAKQKNNGQNLEEDAGQNEQKTDLPSTEKTLMEEKVKLEEQLKETMEKYKRALADTENLRQRSQKLVEEAKLYGIQGFCKDLLEVADILEKATQCVPQEEIRDDNPHLKSLYEGLVMTEVQIQKVFTKHGLLRLNPLGAKFDPYEHEALFHTPVEGKEPGTVALVNKVGYKLHGRTLRPALVGVVKGA

Gene
GRPEL1
Protein
GrpE protein homolog 1, mitochondrial
Organism
Homo sapiens
Length
217 amino acids
Function
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (By similarity). Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (PubMed:11311562).
Similarity
Belongs to the GrpE family.
Mass
24.279 kDa
Sequence
MAAQCVRLARRSLPALALSLRPSPRLLCTATKQKNSGQNLEEDMGQSEQKADPPATEKTLLEEKVKLEEQLKETVEKYKRALADTENLRQRSQKLVEEAKLYGIQAFCKDLLEVADVLEKATQCVPKEEIKDDNPHLKNLYEGLVMTEVQIQKVFTKHGLLKLNPVGAKFDPYEHEALFHTPVEGKEPGTVALVSKVGYKLHGRTLRPALVGVVKEA

Gene
Grpel1
Protein
GrpE protein homolog 1, mitochondrial
Organism
Mus musculus
Length
217 amino acids
Function
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity).
Similarity
Belongs to the GrpE family.
Mass
24.307 kDa
Sequence
MAARCVRLARRSLPALALSFRPSPRLLCTATKQKNNGQNLDEDLGHCEPKTDPPSADKTLLEEKAKLEEQLRETMEKYKRALADTENLRQRSQKLVEEAKLYGIQGFCKDLLEVADILEKATQSVPKEEISNNNPHLKSLYEGLVMTEVQIQKVFTKHGLLRLDPIGAKFDPYEHEALFHTPVEGKEPGTVALVSKVGYKLHGRTLRPALVGVVKDA

Gene
GRPEL1
Protein
GrpE protein homolog 1, mitochondrial
Organism
Pongo abelii
Length
217 amino acids
Function
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity).
Similarity
Belongs to the GrpE family.
Mass
24.279 kDa
Sequence
MAAQCVRLARRSLPALALSLRPSPRLLCTATKQKNSGQNLEEDMGQSEQKADPPATEKTLLEEKVKLEEQLKETVEKYKRALADTENLRQRSQKLVEEAKLYGIQAFCKDLLEVADVLEKATQCVPKEEIKDDNPHLKNLYEGLVMTEVQIQKVFTKHGLLKLNPVGAKFDPYEHEALFHTPVEGKEPGTVALVSKVGYKLHGRTLRPALVGVVKEA

Gene
Grpel1
Protein
GrpE protein homolog 1, mitochondrial
Organism
Rattus norvegicus
Length
217 amino acids
Function
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins.
Similarity
Belongs to the GrpE family.
Mass
24.297 kDa
Sequence
MAARCVRLARRSLPALALSFRPSPRLLCTATKQKNNGQNLEEDLGHCEPKTDPSSADKTLLEEKVKLEEQLKETMEKYKRALADTENLRQRSQKLVEEAKLYGIQGFCKDLLEVADILEKATQSVPKEEVSNNNPHLKSLYEGLVMTEVQIQKVFTKHGLLRLDPIGAKFDPYEHEALFHTPVEGKEPGTVALVSKVGYKLHGRTLRPALVGVVKDA