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GPX5

Gene
GPX5
Protein
Epididymal secretory glutathione peroxidase
Organism
Canis lupus familiaris
Length
221 amino acids
Function
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids.
Similarity
Belongs to the glutathione peroxidase family.
Mass
25.338 kDa
Sequence
MTAWLGASYVLPILLVSFVQTNAKPEKTKMDCYKDVKGTIYEYEALTLNGNERIQFKQYPRKHVLFVNVATYCGLTAQYPELNSLQEELKPLGLVVLGFPCNQFGKQGPGENSEILPGLKYVRPGRGYVPNFQLFEKGDVNGEKEQKVFTFLKLSCPHPSEVLGSFRHISWDPVKVHDIRWNFEKFLVGPDGVPVLRWFHRTPISTVKEDILVYLKQLKMK
Protein
Epididymal secretory glutathione peroxidase: GPX5

Gene
GPX5
Protein
Epididymal secretory glutathione peroxidase
Organism
Homo sapiens
Length
221 amino acids
Function
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids.
Similarity
Belongs to the glutathione peroxidase family.
Mass
25.202 kDa
Sequence
MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYVGKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLKYVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIRWNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK
Protein
Epididymal secretory glutathione peroxidase: GPX5

Gene
GPX5
Protein
Epididymal secretory glutathione peroxidase
Organism
Macaca fascicularis
Length
221 amino acids
Function
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids.
Similarity
Belongs to the glutathione peroxidase family.
Mass
25.212 kDa
Sequence
MTTQLRVVHLLPLLLACFVQTSPKQETMKMDCHKDEKGTIYDYEAIALNKNEYVPFKQYVGKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLKYVRPGGGFVPNFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIRWNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK
Protein
Epididymal secretory glutathione peroxidase: GPX5

Gene
Gpx5
Protein
Epididymal secretory glutathione peroxidase
Organism
Mus musculus
Length
221 amino acids
Function
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids.
Similarity
Belongs to the glutathione peroxidase family.
Mass
25.393 kDa
Sequence
MVTELRVFYLVPLLLASYVQTTPRPEKMKMDCYKDVKGTIYDYEALSLNGKEHIPFKQYAGKHVLFVNVATYCGLTIQYPELNALQEDLKPFGLVILGFPCNQFGKQEPGDNLEILPGLKYVRPGKGFLPNFQLFAKGDVNGENEQKIFTFLKRSCPHPSETVVMSKHTFWEPIKVHDIRWNFEKFLVGPDGIPVMRWFHQAPVSTVKSDIMAYLSHFKTI
Protein
Epididymal secretory glutathione peroxidase: Gpx5

Gene
Gpx5
Protein
Epididymal secretory glutathione peroxidase
Organism
Rattus norvegicus
Length
221 amino acids
Function
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids.
Similarity
Belongs to the glutathione peroxidase family.
Mass
25.385 kDa
Sequence
MAIQLRVFYLVPLLLASYVQTTPRLEKMKMDCYKDVKGTIYNYEALSLNGKERIPFKQYAGKHVLFVNVATYCGLTIQYPELNALQDDLKQFGLVILGFPCNQFGKQEPGDNTEILPGLKYVRPGKGFLPNFQLFAKGDVNGEKEQEIFTFLKRSCPHPSETVVTSKHTFWEPIKVHDIRWNFEKFLVGPNGVPVMRWFHQAPVSTVKSDILAYLNQFKTI
Protein
Epididymal secretory glutathione peroxidase: Gpx5

Gene
GPX5
Protein
Epididymal secretory glutathione peroxidase
Organism
Sus scrofa
Length
219 amino acids
Function
May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Since the purified porcine enzyme has very little activity towards hydrogen peroxide or organic hydroperoxides the protective effect is not likely to be exerted by its enzymatic activity. Instead, may protect sperm from premature acrosome reaction in the epididymis by binding to lipid peroxides, which might otherwise interact with phospholipase A2 and induce the acrosome reaction.
Similarity
Belongs to the glutathione peroxidase family.
Mass
24.936 kDa
Sequence
MTVQLGAFYLFPLFMAGFVQTNSNLEKMDCYKDVTGTIYDYDAFTLNGNEHIQFKQYAGKHVLFVNVATYCGLTAQYPELNTLQEELKPFGLVVLGFPCNQFGKQEPGENSEILLGLKYVRPGGGYVPNFQLFEKGDVNGEKEQKVFTFLKHSCPHPSELIGSIGYISWEPIRVHDIRWNFEKFLVGPDGVPVMRWVHETPISTVKSDILAYLKQFKTE
Protein
Epididymal secretory glutathione peroxidase: GPX5

Gene
GPX5
Protein
Probable glutathione peroxidase 5
Organism
Arabidopsis thaliana
Length
173 amino acids
Function
May constitute a glutathione peroxidase-like protective system against oxidative stresses.
Similarity
Belongs to the glutathione peroxidase family.
Mass
19.327 kDa
Sequence
MGASSSSSVSEKSIHQFTVKDSSGKEVDLSVYQGKVLLVVNVASKCGFTESNYTQLTELYRKYKDQGFVVLAFPCNQFLSQEPGTSEEAHQFACTRFKAEYPVFQKVRVNGQNAAPVYKFLKSKKPSFLGSRIKWNFTKFLVGKDGQVIDRYGTTVSPLSIQKDIEKALAQEL
Protein
Probable glutathione peroxidase 5: GPX5