Function
Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
Sequence
MKFLVENINKNSGRLGLLDLKAAGGGIQLKTPLLMQTTKGGSIPYLSADLFENYVQNKNGQEPVPVLLQLTLSTMQQMAESLALWPASLSHYLGFPGQGNVLLLRDPCESTPSGGNDRDVAPIFTRQGKESLTPERYMEIIASFKPDIYQGLCDADTNLESSKKRVQKSVDRTERFMDYIYEQHGKLQSTSSSLLAPIVGGYNIFARTQSIKHARQQPEGKYSGYILEGFHNNGLSATALDGSQLLPIVEHCVKQLEENKIKMMPGAYSPLIILELIHIGVDVFDTSYAYCAAVNFKALVFNYDEKSIEPRPTPFLDITDEAIKEEFVPLLDNCKCLTCQKHTRAYVHHLYKTNELLGPILLMIHNLHHFMGFFETIRSSIAQDKLPKLIDLVCKQNGDSKVDYSIEKNVKVISKAVVGKGFETTTES