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GIF1

Gene
GIF1
Protein
GRF-interacting factor 1
Organism
Zea mays
Length
227 amino acids
Function
Transcription coactivator that plays a role in the regulation of meristematic function in leaves, stems and inflorescences (PubMed:29437990). Regulates shoot architecture and meristem determinacy (PubMed:29437990). Binds to the inflorescence architecture gene UB3 (unbranched3) (PubMed:29437990). Regulates the expression of several genes involved in inflorescence architecture (PubMed:29437990). Component of a network formed by the microRNA396 (miRNA396), the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation (Probable) (PubMed:26036253). Associates with the core SWI/SNF chromatin-remodeling complex and specific GRFs to tightly regulate the transition between cell division and cell expansion in growing leaves (PubMed:26036253).
Similarity
Belongs to the SS18 family.
Mass
23.603 kDa
Sequence
MQQQHLMQMNQNMMGGYTSPAAVTTDLIQQYLDENKQLILAILDNQNNGKAEECERHQAKLQHNLMYLAAIADSQPPQTAPLSQYPSNLMMQPGPRYMPPQSGQMMNPQSLMAARSSMMYAHPSLSPLQQQQAAHGQLGMAPGGGGGGTTSGFSILHGEASMGGGGAGAGAGNNMMNAGMFSGFGRSGSGAKEGSTSLSVDVRGGTSSGAQSGDGEYLKVGTEEEGS

Gene
GIF1
Protein
GRF-interacting factor 1
Organism
Oryza sativa subsp. japonica
Length
227 amino acids
Function
Transcription coactivator that plays a role in the regulation of meristematic function in leaves, stems and inflorescences (PubMed:29051769, PubMed:29567670). May regulate leaf size, length of stem internodes, and seed size by promoting cell expansion (PubMed:29051769) (Probable). Transcription coactivator that plays a role in the regulation of grain size (PubMed:27107174, PubMed:29051769, PubMed:29567670). Component of a network formed by the microRNA396 (miRNA396), the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation (Probable). Component of the miRNA396c-GRF4-GIF1 regulatory module that plays an important role in grain size determination (PubMed:27107174).
Similarity
Belongs to the SS18 family.
Mass
23.525 kDa
Sequence
MQQQHLMQMNQGMMGGYASPTTVTTDLIQQYLDENKQLILAILDNQNNGKVEECARNQAKLQHNLMYLAAIADSQPPQTAAMSQYPSNLMMQSGARYMPQQSAQMMAPQSLMAARSSMMYAQPALSPLQQQQQQQAAAAHGQLGMGSGGTTSGFSILHGEASMGGGGGGGGAGNSMMNAGVFSDFGRGGGGGGKEGSTSLSVDVRGANSGAQSGDGEYLKGTEEEGS

Gene
GIF1
Protein
GRF-interacting factor 1
Organism
Zea mays
Length
227 amino acids
Function
Transcription coactivator that plays a role in the regulation of meristematic function in leaves, stems and inflorescences (PubMed:29437990). Regulates shoot architecture and meristem determinacy (PubMed:29437990). Binds to the inflorescence architecture gene UB3 (unbranched3) (PubMed:29437990). Regulates the expression of several genes involved in inflorescence architecture (PubMed:29437990). Component of a network formed by the microRNA396 (miRNA396), the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation (Probable) (PubMed:26036253). Associates with the core SWI/SNF chromatin-remodeling complex and specific GRFs to tightly regulate the transition between cell division and cell expansion in growing leaves (PubMed:26036253).
Similarity
Belongs to the SS18 family.
Mass
23.603 kDa
Sequence
MQQQHLMQMNQNMMGGYTSPAAVTTDLIQQYLDENKQLILAILDNQNNGKAEECERHQAKLQHNLMYLAAIADSQPPQTAPLSQYPSNLMMQPGPRYMPPQSGQMMNPQSLMAARSSMMYAHPSLSPLQQQQAAHGQLGMAPGGGGGGTTSGFSILHGEASMGGGGAGAGAGNNMMNAGMFSGFGRSGSGAKEGSTSLSVDVRGGTSSGAQSGDGEYLKVGTEEEGS

Gene
GIF1
Protein
GRF-interacting factor 1
Organism
Oryza sativa subsp. japonica
Length
227 amino acids
Function
Transcription coactivator that plays a role in the regulation of meristematic function in leaves, stems and inflorescences (PubMed:29051769, PubMed:29567670). May regulate leaf size, length of stem internodes, and seed size by promoting cell expansion (PubMed:29051769) (Probable). Transcription coactivator that plays a role in the regulation of grain size (PubMed:27107174, PubMed:29051769, PubMed:29567670). Component of a network formed by the microRNA396 (miRNA396), the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation (Probable). Component of the miRNA396c-GRF4-GIF1 regulatory module that plays an important role in grain size determination (PubMed:27107174).
Similarity
Belongs to the SS18 family.
Mass
23.525 kDa
Sequence
MQQQHLMQMNQGMMGGYASPTTVTTDLIQQYLDENKQLILAILDNQNNGKVEECARNQAKLQHNLMYLAAIADSQPPQTAAMSQYPSNLMMQSGARYMPQQSAQMMAPQSLMAARSSMMYAQPALSPLQQQQQQQAAAAHGQLGMGSGGTTSGFSILHGEASMGGGGGGGGAGNSMMNAGVFSDFGRGGGGGGKEGSTSLSVDVRGANSGAQSGDGEYLKGTEEEGS

Gene
GIF1
Protein
GRF1-interacting factor 1
Organism
Arabidopsis thaliana
Length
210 amino acids
Function
Transcription coactivator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. Appears to function synergistically with GRF1 as a transcriptional coactivator. Acts together with GRF5 for the development of appropriate leaf size and shape through the promotion and/or maintenance of cell proliferation activity in leaf primordia. Plays a role in adaxial/abaxial patterning and growth in leaf morphogenesis. GIFs are involved in the positive regulation of cell proliferation of lateral organs in a functionally redundant manner. Together with GATA18/HAN, mediates cotyledon identity by preventing ectopic root formation through the repression of PLT1 expression (PubMed:22669825).
Similarity
Belongs to the SS18 family.
Mass
22.464 kDa
Sequence
MQQHLMQMQPMMAGYYPSNVTSDHIQQYLDENKSLILKIVESQNSGKLSECAENQARLQRNLMYLAAIADSQPQPPSVHSQYGSAGGGMIQGEGGSHYLQQQQATQQQQMTQQSLMAARSSMLYAQQQQQQQPYATLQHQQLHHSQLGMSSSSGGGGSSGLHILQGEAGGFHDFGRGKPEMGSGGGGEGRGGSSGDGGETLYLKSSDDGN

Gene
GIF1
Protein
GRF1-interacting factor 1
Organism
Arabidopsis thaliana
Length
210 amino acids
Function
Transcription coactivator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. Appears to function synergistically with GRF1 as a transcriptional coactivator. Acts together with GRF5 for the development of appropriate leaf size and shape through the promotion and/or maintenance of cell proliferation activity in leaf primordia. Plays a role in adaxial/abaxial patterning and growth in leaf morphogenesis. GIFs are involved in the positive regulation of cell proliferation of lateral organs in a functionally redundant manner. Together with GATA18/HAN, mediates cotyledon identity by preventing ectopic root formation through the repression of PLT1 expression (PubMed:22669825).
Similarity
Belongs to the SS18 family.
Mass
22.464 kDa
Sequence
MQQHLMQMQPMMAGYYPSNVTSDHIQQYLDENKSLILKIVESQNSGKLSECAENQARLQRNLMYLAAIADSQPQPPSVHSQYGSAGGGMIQGEGGSHYLQQQQATQQQQMTQQSLMAARSSMLYAQQQQQQQPYATLQHQQLHHSQLGMSSSSGGGGSSGLHILQGEAGGFHDFGRGKPEMGSGGGGEGRGGSSGDGGETLYLKSSDDGN