GAREM2

Gene

Garem2

Protein

GRB2-associated and regulator of MAPK protein 2

Organism

Mus musculus

Length

880 amino acids

Function

Probable adapter protein that provides a critical link between cell surface epidermal growth factor receptor and the MAPK/ERK signaling pathway.

Similarity

Belongs to the GAREM family.

Mass

93.51 kDa

Sequence

MEKLAAGLAGLRWSMGAFPLDLIVSRCRLPTLACLGPGEYAEGVSERDILLIHSCRQWTTVTAHTLEEGHYVIGPKIDIPLQYPGKFKLLEQARDVREPVRYFSSVEEVASVFPDRIFVMEAITFSVKVVSGEFSEDSEVYNFTLHAGDELTLMGQAEILCAKTTKERSRFTTLLRKLGRAGALAGIGGPGSMGATGGGGGAARPVKSKMPCLICMNHRTNESLSLPFQCQGRFSTRSPLELQMQEGEHTVRAIIERVRLPVNVLVPSRPPRNPYDLHPVREGHCYKLVSIISKTVVLGLALRREGPAPLHFLLLTDTPRFTLPQGLLAGDPRVERLVRDSASYCRERFDPDEYSTAVREAPAELSDDCASPRHARLCLPAPRAPGAVRAPGPPGRLGPALPAPGDSDQDYVSPDWAGVSEPAGGCAEIPYEELWVHQAPESRADARARPLAGPDLISFGIVGPPRHEPEAPPPPVPPKSEAVKEECRLLHAPPVPPRGGGSCSKLTGSPPVLPHFPKLQPVHSPSSSLSYYSSGLQDGAGSRSGSGSPSPDAYSLYCYPCTWGDCKASESSSRPPPGPLPSTTTQPSQASRGLSEPLSGRTPSLLGADTPVVKNYHSCPPLFKSSRPQKSFAPFGALNPFSGPAHPSGAPAASSSGSISTSGVLATSSPTHSPGPGPGPQGQGYSAAPSSSLSSSEWQEPALEPLDPFELGQASPPELELVRCQEPRAAGAPGSGPCLSPLGQPKAFEPEGLVLRQVPASLSPAALQGPEAGGTLLFLTQGCLEGPPGSPREGATGAGVRDASSWQPPADLSALSLEEVSRSLRFIGLSEDVVSFFARERIDGSIFVQLSEDILADDFHLTKLQVKKIMQFIKGWRPKI

Protein

GRB2-associated and regulator of MAPK protein 2: Garem2

Gene

GAREM2

Protein

GRB2-associated and regulator of MAPK protein 2

Organism

Homo sapiens

Length

874 amino acids

Function

Probable adapter protein that may provide a link between cell surface epidermal growth factor receptor and the MAPK/ERK signaling pathway.

Similarity

Belongs to the GAREM family.

Mass

92.882 kDa

Sequence

MEKLAAGLAGLRWSMGAFPLDLIVSRCRLPTLACLGPGEYAEGVSERDILLIHSCRQWTTVTAHTLEEGHYVIGPKIDIPLQYPGKFKLLEQARDVREPVRYFSSVEEVASVFPDRIFVMEAITFSVKVVSGEFSEDSEVYNFTLHAGDELTLMGQAEILCAKTTKERSRFTTLLRKLGRAGALAGVGGGGPASAGAAGGTGGGGARPVKGKMPCLICMNHRTNESLSLPFQCQGRFSTRSPLELQMQEGEHTVRAIIERVRLPVNVLVPSRPPRNPYDLHPVREGHCYKLVSIISKTVVLGLALRREGPAPLHFLLLTDTPRFALPQGLLAGDPRVERLVRDSASYCRERFDPDEYSTAVREAPAELAEDCASPRRARLCLPAPRAPGLARAPGPLAPAPAGEGDQEYVSPDWAAAPEPAAPPAEIPYEELWAHQGPEGLVRPPPGLDLISFGAAGPPRREPEAPPPPVPPKSEAVKEECRLLNAPPVPPRGGNGSGRLSSSPPVPPRFPKLQPVHSPSSSLSYYSSGLQDGAGSRSGSGSPSPDTYSLYCYPCTWGDCKVGESSSRPAPGPLPSTTQPSQASRALTEPLSGRAASLLGADTPVKTYHSCPPLFKPSHPQKRFAPFGALNPFSGPAYPSGPSAALSSGPRTTSGPVATSGPAYSPGPASPGQAYSAAPPSSCAPSSSSSSEWQEPVLEPFDPFELGQGSSPEPELLRSQEPRAVGTPGPGPRLSPLGPSKAFEPEGLVLHQVPTPLSPAALQGPEAGGALFLTQGRLEGPPASPRDGATGFGVRDASSWQPPADLSALSLEEVSRSLRFIGLSEDVVSFFARERIDGSIFVQLSEDILADDFHLTKLQVKKIMQFIKGWRPKI

Protein

GRB2-associated and regulator of MAPK protein 2: GAREM2