Protein
Hydrophobic dipeptide epimerase
Organism
Flavobacteria bacterium (strain MS024-2A)
Function
Catalyzes the epimerization a variety of hydrophobic dipeptides. Epimerase activity is highest with L-Ala-L-Tyr, and lower with L-Ala-L-Met, L-Ala-L-Phe, L-Tyr-L-Ala, L-Tyr-L-Met and L-Tyr-L-Trp (in vitro).
Similarity
Belongs to the mandelate racemase/muconate lactonizing enzyme family.
Sequence
MKFTFHKVTLKKRFPLAISRGVRYNSENLFVCYEKDGHIGWGEAAPGNSEGAATAEAVQEALENFIATGIEGFSIQELYDRAREMKIPPCAYVALDTAFWDWTAKKAQLPLRQLLGFSKPHTPTSVTIGINPPEVIKERVPLLLEGTTVQSLKIKLGSPEGIDADKTMFEQVVESTKKYPVKLRVDANGGWDVNQAQHMMQWLADRKVDYIEQPLKEGDEAGLKTLFKSRPLPIYVDESCRFSQNIPSFAAHVDGVNMKLMKCGGITEALRIIGTARAHGLKTMIGCMSESSVAIAAAAAMTGGIDHIDLDSHYNLAPDPAHGAPLINGVTLPPEIPGHGAYLKEEFYA