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FLCY

Gene
FLCY
Protein
Farnesylcysteine lyase
Organism
Arabidopsis thaliana
Length
500 amino acids
Function
Involved in the degradation of prenylcysteine. Cleaves specifically the thioether bond of S-farnesyl-L-cysteine and has no activity with S-geranylgeranyl-L-cysteine. Recognizes also N-acetyl-farnesylcysteine and may have a role in deprenylation of farnesylated proteins.
Similarity
Belongs to the prenylcysteine oxidase family.
Mass
55.298 kDa
Sequence
MKDFPIAISLLFALLSPVLLPCSGDSTGGVEDDSPATVCIVGSGIGGSSVAHFLRNYSVSTGLNQAKILMFERHEIVGGRMRTVTVAGDTFEAGGSILHPKNYHVKDFVERFNLTVRLPTPIEESSAIGIWDGKRFVVKTFGSGTKFPFLDTIVSWVNDLYLFLRYGLSLLRMSSFIENTVDNFLKYYESLESRPIFDNVEGMLKWSGLYNLTKLTLQEKLSEAQLSPLLVNELVTVITRINYGQSVLISGLAGAVSLAGSGGGLWSVEGGNWQMAAKLINHSDVTLHLNEKIESISYLENHYELKSTKGNSYKCDVTVVATPLDEVDIQFSPTISIPKRELQHTHTTFVRGLLNPGYFGMKSLSDVPALVGTLEDPLIPFSCISILRKYSKTDMTYKIFTRQPASDSLLDELFSRRTETVRIDWGAYPKYHAPEVFAPFILDDHHLYYVNAFENAASTMETSAVAGENIARLIISRFMTKESLSSSDKRSCSSGLHSDS