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FBLIM1

Gene
FBLIM1
Protein
Filamin-binding LIM protein 1
Organism
Bos taurus
Length
378 amino acids
Function
Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion (By similarity).
Mass
41.497 kDa
Sequence
MASKPEKRVASSVFITLVPPRRDEAVVEEVRRAACEAWPGRPWESAPTKAPGAGSVGKLRSWMPPGRAAAPGPAVPPQLSNGGCSLPPPPLDVDDALPDLDLLPPPPPPPAADLPPPDEEPHSAMGASLISDLEQLHLPPPPPPPQALVEGPPLQPRPSHLKPAEEELPPPPEEPVSFPEREASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRVCRRQLAGQSFYQKDGRPLCEPCYQDTLEKCGKCGEVVREHIIRALGQAFHPSCFTCVTCARRIGDESFALDSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRVLLSVEPTDQGCYPLNNRLFCKPCHVKRSAAGCC

Gene
Fblim1
Protein
Filamin-binding LIM protein 1
Organism
Mus musculus
Length
375 amino acids
Function
Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion (By similarity).
Mass
41.026 kDa
Sequence
MASKPEKRVASSVFITLAPPRRDVAVSEEVGQAACEARRARPWEMLPTKTPGAAVGRSPKTWTPSGKTNASLSGVTPQLSNGGCSLPPPSLNEEDLDLPPPPPPPSAYLPLPEEEPPVLPGKSLISDLEQLHLPPPPPPPPPQAPSKGSSVHPPPGHAIPSEEELPPPPEEPVTLPEREVSTDVCGFCHKPVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQRFYQKDGRPLCEPCYQDTLEKCGKCGEVVQEHVIRALGKAFHPPCFTCVTCARCISDESFALDSQNQVYCVADFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCSVLLSVEPTDQGCYPLNDHLFCKPCHLKRSAAGCC

Gene
FBLIM1
Protein
Filamin-binding LIM protein 1
Organism
Pongo abelii
Length
375 amino acids
Function
Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion (By similarity).
Mass
41.108 kDa
Sequence
MASKPEKRVASSVFITLAPLRRDVAMAEEVRQAVCEARRGRPWEAPAPMKTPEAGLEGRPSPWTPPGRAAATVPAAPMQLSNGGCPPPPPVLDGEDALPDLDLFPPPPPPPPVLLPSEEEAPAPMGASLIADLEQLHLSPPLPPPPPQAPAERPSVQPSPLRPMEEELPPPPAERVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRSFHENCYRCEDCRILLSVEPTDQGCYPLNNRLFCKPCHVKRSAAGCC

Gene
FBLIM1
Protein
Filamin-binding LIM protein 1
Organism
Homo sapiens
Length
373 amino acids
Function
Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion.
Mass
40.67 kDa
Sequence
MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRPSPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEEAPAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGCC