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FATE1

Gene
FATE1
Protein
Fetal and adult testis-expressed transcript protein
Organism
Homo sapiens
Length
183 amino acids
Function
Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis (PubMed:27402544). May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling (PubMed:26567849).
Mass
20.712 kDa
Sequence
MAGGPPNTKAEMEMSLAEELNHGRQGENQEHLVIAEMMELGSRSRGASQKKQKLEQKAAGSASAKRVWNMTATRPKKMGSQLPKPRMLRESGHGDAHLQEYAGNFQGIRFHYDRNPGTDAVAQTSLEEFNVLEMEVMRRQLYAVNRRLRALEEQGATWRHRETLIIAVLVSASIANLWLWMNQ

Gene
FATE1
Protein
Fetal and adult testis-expressed transcript protein homolog
Organism
Bos taurus
Length
180 amino acids
Function
Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling.
Mass
20.36 kDa
Sequence
MAGGAVPNLKEKMQVPKDEDLLLGSFRDNQECSVAAEMKEHMSRLLGASQRRQRVDPKAVGSAVVWNTAANQSKKMGPQLRGVGVVGEQGDGGAQPQENPGGSQGMRSQFERRELNTLAEIGLEELNELEMEIMRRQLFMITERLRYLEDQSATWHQREVLLFTMLLSSCITNLWLWMRQ

Gene
FATE1
Protein
Fetal and adult testis-expressed transcript protein homolog
Organism
Sus scrofa
Length
171 amino acids
Function
Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling.
Mass
19.065 kDa
Sequence
MAGGSTNTKKIEMSLAEELVPKSQEPSREQVLIAEMLEHGIRSLGASQSRQKLDSKISDSAAAWNLAANKSKKTGPQLPPKKASQEPNQEGGFQGMGFLYERNLGADVIAEIGLEELNGLEMEIMRRQLQVITGRLRALEDQGATWRHRETLFFTMLVSVCVANLWLWLRQ

Gene
Fate1
Protein
Fetal and adult testis-expressed transcript protein homolog
Organism
Mus musculus
Length
99 amino acids
Function
Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling.
Mass
11.726 kDa
Sequence
MPWVPREHSHDDVQLQEFSRNFPVGRFPYECLEADIMAKIGLEELNGLEMEVMRRQMQMTSGRLHILEDQDATWCHKEAALFTLLVSVCIANLWLWVHW