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FAH

Gene
FAH
Protein
Fumarylacetoacetase
Organism
Oryza sativa subsp. japonica
Length
429 amino acids
Function
Converts fumarylacetoacetate to acetoacetate and fumarate. Involved in tyrosine catabolic pathway. Catalyzes the final step in the tyrosine degradation pathway.
Similarity
Belongs to the FAH family.
Mass
47.105 kDa
Sequence
MAEGSRSPLRSFVEVAPGSHFPIQNLPFGVFRRRGSPEPEPPRPAVAIGDFALDLAAVSDAGLFHGPLLSASPCFRQETLNMFLGMGRPAWKEARATLQKILSADEPVLRDNEALKKKCLVPMSDTEMLLPITVGDYTDFFCSVHHARNCGFIFRGPQTPVNPNWFQLPVGYHGRASSVIVSGTDIIRPKGQGHPTGDSRPYFGPSKKLDFELEMAAIVGPGNELGKPIDINDAEEHIFGLMIMNDWSARDIQAWETIPLGPFLGKSFSTTVSPWIVTMDALKPFTCEAPKQEPEPLPYLAEKNHVNYDIPLEVWIKPKEQSEPSMVAKSNFKHLYWTLTQQLAHHTVNGCNLRPGDMFATGTLSGPETESLGCLLELTWNGQKEISVGNSTRKFLEDGDEVILTACCKGEGYNVGFGTCTGKVLPALP
Protein
Fumarylacetoacetase: FAH

Gene
fah
Protein
Fumarylacetoacetase
Organism
Dictyostelium discoideum
Length
427 amino acids
Similarity
Belongs to the FAH family.
Mass
47.429 kDa
Sequence
MSILKSFIEVSEDSHFPIQNLPYGVFKPTLNDQARIGVAIGDFVCDLSVLADLKLFDGKLKDTKVFHQENLNSFMSLGKELWSEARKTIQNLLSSETSTIRDNKEYREKIFHSISSVTMLLPARIGDYTDFYASKEHATNVGIMFRGKENALMPNWVHLPVGYHGRSSSIVVSGTPLKRPWGQTKSDEPDSLPTFNPCRLLDFELEMGALIGGESTKLGEPISIESAKDHIFGLVLLNDWSARDIQKWEYVPLGPFLAKNFGSTISPWVVTMEALQPFATKPPTQDPQPMKYLQEQGNTTFDIELSVSIKSPKMSKPHKVSTSNLKYMYWTLTQQLAHHTVNGCNMNAGDLLGTGTISGPTEDSYGSMLELSWKGSKVVSLGTETNEERKFIQDGDSVILSGLCKGNGYQIGFGNCEGTILPADKRQ
Protein
Fumarylacetoacetase: fah

Gene
FAH
Protein
Fumarylacetoacetase
Organism
Arabidopsis thaliana
Length
421 amino acids
Function
Converts fumarylacetoacetate to acetoacetate and fumarate (PubMed:22980205). Involved in tyrosine catabolic pathway. Catalyzes the final step in the tyrosine degradation pathway (PubMed:22980205, PubMed:23743712, PubMed:27097641).
Similarity
Belongs to the FAH family.
Mass
46.095 kDa
Sequence
MALLKSFIDVGSDSHFPIQNLPYGVFKPESNSTPRPAVAIGDLVLDLSAISEAGLFDGLILKDADCFLQPNLNKFLAMGRPAWKEARSTLQRILSSNEPILRDNDVLRRKSFHQMSKVEMIVPMVIGDYTDFFASMHHAKNCGLMFRGPENAINPNWFRLPIAYHGRASSIVISGTDIIRPRGQGHPQGNSEPYFGPSKKLDFELEMAAVVGPGNELGKPIDVNNAADHIFGLLLMNDWSARDIQAWEYVPLGPFLGKSFGTTISPWIVTLDALEPFGCQAPKQDPPPLPYLAEKESVNYDISLEVQLKPSGRDDSCVITKSNFQNLYWTITQQLAHHTVNGCNLRPGDLLGTGTISGPEPDSYGCLLELTWNGQKPLSLNGTTQTFLEDGDQVTFSGVCKGDGYNVGFGTCTGKIVPSPP
Protein
Fumarylacetoacetase: FAH

Gene
FAH
Protein
Fumarylacetoacetase
Organism
Bos taurus
Length
419 amino acids
Similarity
Belongs to the FAH family.
Mass
46.156 kDa
Sequence
MSFVPVAEDSDFPIHNLPYGVFSTRGNPRPRIGVAIGDQILDLSVIKHLFTGPILSGHQDVFNKPTLNSFMGLGQAAWKEARAFLQNLLSASQARLRDDVELRQRAFTSQASATMYLPATIGDYTDFYSSRHHATNVGVMFRGKENALMPNWLHLPVGYHGRASSVVVSGTPIRRPLGQMRPDDSKPPVYGACKLLDFELEMAFFVGPGNKLGEPIPISKAHEHIFGMVLMNDWSARDIQKWEYVPLGPFLGKSFGTTISPWVVPMDALMPFAVSNPEQDPKPLPYLCHDQPYTFDINLSVALKGEGMSQAATICRSNFKYMYWTMLQQLTHHSVNGCNLQPGDLLASGTISGPEPESFGCMLELSWKGTRAVELGNGQTRKFLLDGDEVIMTGHCQGDGYRIGFGQCAGKVLPALSFA
Protein
Fumarylacetoacetase: FAH

Gene
FAH
Protein
Fumarylacetoacetase
Organism
Homo sapiens
Length
419 amino acids
Similarity
Belongs to the FAH family.
Mass
46.374 kDa
Sequence
MSFIPVAEDSDFPIHNLPYGVFSTRGDPRPRIGVAIGDQILDLSIIKHLFTGPVLSKHQDVFNQPTLNSFMGLGQAAWKEARVFLQNLLSVSQARLRDDTELRKCAFISQASATMHLPATIGDYTDFYSSRQHATNVGIMFRDKENALMPNWLHLPVGYHGRASSVVVSGTPIRRPMGQMKPDDSKPPVYGACKLLDMELEMAFFVGPGNRLGEPIPISKAHEHIFGMVLMNDWSARDIQKWEYVPLGPFLGKSFGTTVSPWVVPMDALMPFAVPNPKQDPRPLPYLCHDEPYTFDINLSVNLKGEGMSQAATICKSNFKYMYWTMLQQLTHHSVNGCNLRPGDLLASGTISGPEPENFGSMLELSWKGTKPIDLGNGQTRKFLLDGDEVIITGYCQGDGYRIGFGQCAGKVLPALLPS
Protein
Fumarylacetoacetase: FAH

Gene
Fah
Protein
Fumarylacetoacetase
Organism
Mus musculus
Length
419 amino acids
Similarity
Belongs to the FAH family.
Mass
46.176 kDa
Sequence
MSFIPVAEDSDFPIQNLPYGVFSTQSNPKPRIGVAIGDQILDLSVIKHLFTGPALSKHQHVFDETTLNNFMGLGQAAWKEARASLQNLLSASQARLRDDKELRQRAFTSQASATMHLPATIGDYTDFYSSRQHATNVGIMFRGKENALLPNWLHLPVGYHGRASSIVVSGTPIRRPMGQMRPDNSKPPVYGACRLLDMELEMAFFVGPGNRFGEPIPISKAHEHIFGMVLMNDWSARDIQQWEYVPLGPFLGKSFGTTISPWVVPMDALMPFVVPNPKQDPKPLPYLCHSQPYTFDINLSVSLKGEGMSQAATICRSNFKHMYWTMLQQLTHHSVNGCNLRPGDLLASGTISGSDPESFGSMLELSWKGTKAIDVEQGQTRTFLLDGDEVIITGHCQGDGYRVGFGQCAGKVLPALSPA
Protein
Fumarylacetoacetase: Fah

Gene
Fah
Protein
Fumarylacetoacetase
Organism
Rattus norvegicus
Length
419 amino acids
Similarity
Belongs to the FAH family.
Mass
45.976 kDa
Sequence
MSFIPVAEDSDFPIQNLPYGVFSTQSNPKPRIGVAIGDQILDLSVIKHLFTGPVLSKHQHVFDETTLNSFMGLGQAAWKEARASLQNLLSASQAQLRDDKELRQRAFTSQASATMHLPATIGDYTDFYSSLQHATNVGIMFRGKENALLPNWLHLPVGYHGRASSVVVSGTPIRRPMGQMRPDNSKPPVYGASKRLDMELEMAFFVGPGNRFGEPIPISKAQEHIFGMVLMNDWSARDIQQWEYVPLGPFLGKSFGTTISPWVVPMDALMPFVVPNPKQDPKPLPYLCHSQPYTFDINLSVALKGEGMSQAATICRSNFKHMYWTILQQLTHHSVNGCNLRPGDLLASGTISGSDPESFGSMLELSWKGTKAIDVGQGQTRTFLLDGDEVIITGHCQGDGYRVGFGQCAGKVLPALSPA
Protein
Fumarylacetoacetase: Fah