About Products Protein Database Contact

FAAP24

Gene
Faap24
Protein
Fanconi anemia core complex-associated protein 24
Organism
Mus musculus
Length
221 amino acids
Function
Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA (By similarity).
Mass
24.641 kDa
Sequence
MERNPPDGTGPVHVPLGHIVASEKWRGSQLAQEMQGKVRLIFEEGLASADFYLSSKSCILYVTEADLVAGHGYRKRLARFRNSSHLQGIIIVEKTQMSEQYFPAVQKFTVLDLGMVLLPVASQSEASCLIIHLVQEQTREPSKNPFLRKKRSMLSELSLVQTVQQIPGVGKVKAPLLLQKFPSIQQLSNASVQELEEVVGPAAAQQIHTFFTQPKRQQPRS

Gene
FAAP24
Protein
Fanconi anemia core complex-associated protein 24
Organism
Bos taurus
Length
215 amino acids
Function
Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA (By similarity).
Mass
23.879 kDa
Sequence
MESNPPDSTGPMHVPFGHIVANEKWRGSQLAQGMQGKIKLVFEDGLTPVDFYLSSKSCILYITEAELVAGNGYRKRLVRVRNSNKLQGIVVVEKTQMSEQYFPAVQKFTVLDLGMVLLPVASQMEASCLIIQLVQEQTREPSKNPFLRKKRALVSEPALLRSVQQIPGVGKVKAPLLLQRFPSIQQLSNASLRELEAVVGPAAAQRIHAFFSQPR

Gene
FAAP24
Protein
Fanconi anemia core complex-associated protein 24
Organism
Homo sapiens
Length
215 amino acids
Function
Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA.
Mass
23.897 kDa
Sequence
MEKNPPDDTGPVHVPLGHIVANEKWRGSQLAQEMQGKIKLIFEDGLTPDFYLSNRCCILYVTEADLVAGNGYRKRLVRVRNSNNLKGIVVVEKTRMSEQYFPALQKFTVLDLGMVLLPVASQMEASCLVIQLVQEQTKEPSKNPLLGKKRALLLSEPSLLRTVQQIPGVGKVKAPLLLQKFPSIQQLSNASIGELEQVVGQAVAQQIHAFFTQPR