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FAAP20

Gene
FAAP20
Protein
Fanconi anemia core complex-associated protein 20
Organism
Bos taurus
Length
192 amino acids
Function
Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1 (By similarity).
Mass
20.654 kDa
Sequence
MEATRRSRLSLSRRRPPLGVRPRSNTAGSLPDGGECAKLWTELLRTASADLNVDGELPPLPAFPDQEPRRSPERPPPETFTVGTETFFWTPFPAPSPGRGGNSGGSDLVLSAVRGRTGSPQQYAAPELRGTPSAEEQPSEEQPSQRQSSVDGAMTLQSCPMCQVDFAPGLAQLDIDGHLAQCLADSTDDIEW

Gene
Faap20
Protein
Fanconi anemia core complex-associated protein 20
Organism
Mus musculus
Length
186 amino acids
Function
Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1 (By similarity).
Mass
20.038 kDa
Sequence
MEEERRLRGRLSRRRPPAGGGPPNCRPWFLSEGSKSEPWAALLRSTVSGTADWTPNRQPLPPLPAFPSQESLPDPESTVPPEAFTVGSKTFSWTPLPPALRGSGSSRHLFCEPEGSLGSPTPSLKGCPALNSGRTPSAQECVPVQSPLALLSCPLCQKAFDPKLTQLDVDSHLAQCLAECTEDVVW

Gene
Faap20
Protein
Fanconi anemia core complex-associated protein 20
Organism
Rattus norvegicus
Length
184 amino acids
Function
Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1 (By similarity).
Mass
20.005 kDa
Sequence
MEEERRLRGRLSRRRPPAGGGPPNCRPWFLSEESKSEPWAALLRSTVGGNTDWTPNSQPLPPLPAFPSQESLPDPESTVPPEVFTVGSKTFSWTPFPPALRGSGSSCRLLRCPEGSPGSPAPSLKGCPALDSRQTPSTQECVQSQLVLLNCPLCQKAFDPKLTQLDVDSHLAQCLAESTEDVVW

Gene
FAAP20
Protein
Fanconi anemia core complex-associated protein 20
Organism
Homo sapiens
Length
180 amino acids
Function
Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1.
Mass
19.869 kDa
Sequence
MEAARRPRLGLSRRRPRPAGGPSGGRPWFLLGGDERERLWAELLRTVSPELILDHEVPSLPAFPGQEPRCGPEPTEVFTVGPKTFSWTPFPPDLWGPGRSYRLLHGAGGHLESPARSLPQRPAPDPCRAPRVEQQPSVEGAAALRSCPMCQKEFAPRLTQLDVDSHLAQCLAESTEDVTW