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Elba2

Gene
Elba2
Protein
Early boundary activity protein 2
Organism
Drosophila melanogaster
Length
381 amino acids
Function
The heterotrimeric Elba complex is required for chromatin domain boundary function during early embryogenesis. It binds to a 8-bp sequence 5'-CCAATAAG-3' in the Fab-7 insulator or boundary element in the bithorax complex and contributes to its insulator or boundary activity (PubMed:23240086). Elba2 can act as a transcriptional repressor and binds the palindromic sequence 5'-CCAATTGG-3' to mediate transcriptional repression (PubMed:25561495).
Mass
43.31 kDa
Sequence
MAGGFRPYDQDSCPNLTNSEAPEFSMSVVCKTEPHYFHPQTAILPSVQYSHPYHHYLSQFAPNFVPYYYRLLSRPIMKQEEMDIENYINYEVAAQQTMMRQRTLKPLGQLQIQMPPPIIVNQPVKPVPVKAVPVRRSSPPKRRVINAQLVAVATASGGIKNIEPRVEPLPRLEESFKQQVAKIQKSQHHYEQLFGRLTSMLKTLNQRYDNDAEDVPAPPSKRPRHMSTSSSESHIPDTASEKDEKDTLVQYPHRVQKEDGSAVYVLGPNGTQITAHQYGEVFWTNAPVATRCLLCVVFSSDELATHTLTGKPSPAFYGRERPPKLQLDQRKVDDIVVCVRNRTGGKERVIRATITTKCADTAKKYKRRAKKAQKVAIKEEY