Egr2

Gene

EGR2

Protein

E3 SUMO-protein ligase EGR2

Organism

Sus scrofa

Length

471 amino acids

Function

E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity.

Similarity

Belongs to the EGR C2H2-type zinc-finger protein family.

Mass

49.911 kDa

Sequence

MMTAKAVDKIPVTLSGFVHQLSDNIYPVEDLAATSVTIFPNAELGSPFDQMNGVAGDGMINIDMTGEKRSLDLPYPSSFAPVSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGILQGVTSPASTTASSNVTSASPNPLATGPLGVCTMSQTQPDLDHLYSPPPPPPYSGCAGDLYQDPSAFLSAATTSTSSSLAYPPPPSYPSPKPATDPGLFPMIPDYPGFFPSQCQRDLHGTAGPDRKPFPCPLDSLRVPPPLTPLSTIRNFTLGGPSAGTTGPGASGGSEGPRLPGSSAAAAAAAYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAPSSSVPAASTASCTGGAQPGGPLCSSNSSTIGGGSLGPCSSRTRTP

Protein

E3 SUMO-protein ligase EGR2: EGR2

Gene

Egr2

Protein

E3 SUMO-protein ligase EGR2

Organism

Mus musculus

Length

470 amino acids

Function

E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity.

Similarity

Belongs to the EGR C2H2-type zinc-finger protein family.

Mass

49.819 kDa

Sequence

MMTAKAVDKIPVTLSGFMHQLPDSLYPVEDLAASSVTIFPNGELGGPFDQMNGVAGDGMINIDMTGEKRPLDLPYPSSFAPISAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGILQGVTPPASTTASSSVTSASPNPLATGPLGVCTMSQTQPELDHLYSPPPPPPPYSGCTGDLYQDPSAFLSPPSTTSTSSLAYQPPPSYPSPKPAMDPGLIPMIPDYPGFFPSPCQRDPHGAAGPDRKPFPCPLDSLRVPPPLTPLSTIRNFTLGGPGAGVTGPGASGGGEGPRLPGSGSAAVTATPYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAPSAPPSAQSSASGPGGSQAGGSLCGNSAIGGPLASCTSRTRTP

Protein

E3 SUMO-protein ligase EGR2: Egr2

Gene

Egr2

Protein

E3 SUMO-protein ligase EGR2

Organism

Rattus norvegicus

Length

470 amino acids

Function

E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity.

Similarity

Belongs to the EGR C2H2-type zinc-finger protein family.

Mass

49.849 kDa

Sequence

MMTAKAVDKIPVTLSGFMHQLPDSLYPVEDLAAPSVTIFPNGELGGPFDQMNGVAGDGMINIDMTGEKRPLDLPYPSSFAPISAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGILQGVTPPASTTASSSVTSASPNPLATGPLGVCTMSQTQPELDHLYSPPPPPPPYSGCTGDLYQDPSAFLSPPPTTSTSSLAYQPPPSYPSPKPAMDPGLIPMIPDYPGFFPSPCQRDPHGAAGPDRKPFPCPLDSLRVPPPLTPLSTIRNFTLGGPSAGVTGPGASGGGEGPRLPGSGSAAVTATPYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAPSSSASAQSSASGPGGSQAGGSLCGNSAIGGPLASCTSRTRTP

Protein

E3 SUMO-protein ligase EGR2: Egr2

Gene

egr2

Protein

Early growth response protein 2

Organism

Xenopus laevis

Length

421 amino acids

Function

Sequence-specific DNA-binding transcription factor.

Similarity

Belongs to the EGR C2H2-type zinc-finger protein family.

Mass

46.38 kDa

Sequence

MAAKAVDKLPVTFGSFVHQIPEGFYPGEDSTLPASVTIFPNVDLGGPLIQMSGVTGDGMISVDMNNDKRSLDFSYSSNYPLAPRTQPIAYMGKISIDHQYSGSGWNTEGIFNLVSAASLLGVPPSSCSSTSSSNASSGSPNLSCSMSHPQSDLEHIYSPPPYSSCNEIYQDPLRFPCGSPTAASLPPPPSYPSPKGASDGGMFPMIPDYSALFPPQCQRDLHSDRKPFPCPRHPSPLSTIRNFTLGGSSEGPRLASAYSPQNLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKNSATAAWRQHVARTSLKPQSGRDRQPCALLGPAAAHWDSIDPNRTG

Protein

Early growth response protein 2: egr2

Gene

egr2

Protein

Early growth response protein 2

Organism

Poecilia reticulata

Length

62 amino acids

Function

Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4.

Similarity

Belongs to the EGR C2H2-type zinc-finger protein family.

Mass

7.247 kDa

Fragment

single

Sequence

AEGCDRGFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGR