ESYT1

Extended synaptotagmin-1

1104 amino acids

Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. Helps tether the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane.

Belongs to the extended synaptotagmin family.

122.856 kDa

MERSPGEGPSPSPMDQPSAPSDPTDQPPAAHAKPDPGSGGQPAGPGAAGEALAVLTSFGRRLLVLIPVYLAGAVGLSVGFVLFGLALYLGWRRVRDEKERSLRAARQLLDDEEQLTAKTLYMSHRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYMEKLLAETVAPAVRGSNPHLQTFTFTRVELGEKPLRIIGVKVHPGQRKEQILLDLNISYVGDVQIDVEVKKYFCKAGVKGMQLHGVLRVILEPLIGDLPFVGAVSMFFIRRPTLDINWTGMTNLLDIPGLSSLSDTMIMDSIAAFLVLPNRLLVPLVPDLQDVAQLRSPLPRGIIRIHLLAARGLSSKDKYVKGLIEGKSDPYALVRLGTQTFCSRVIDEELNPQWGETYEVMVHEVPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQASVLDDWFPLQGGQGQVHLRLEWLSLLSDAEKLEQVLQWNWGVSSRPDPPSAAILVVYLDRAQDLPLKKGNKEPNPMVQLSIQDVTQESKAVYSTNCPVWEEAFRFFLQDPQSQELDVQVKDDSRALTLGALTLPLARLLTAPELILDQWFQLSSSGPNSRLYMKLVMRILYLDSSEICFPTVPGCPGAWDVDSENPQRGSSVDAPPRPCHTTPDSQFGTEHVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKLAGRSFRSHVVREDLNPRWNEVFEVIVTSVPGQELEVEVFDKDLDKDDFLGRCKVRLTTVLNSGFLDEWLTLEDVPSGRLHLRLERLTPRPTAAELEEVLQVNSLIQTQKSAELAAALLSIYMERAEDLPLRKGTKHLSPYATLTVGDSSHKTKTISQTSAPVWDESASFLIRKPHTESLELQVRGEGTGVLGSLSLPLSELLVADQLCLDRWFTLSSGQGQVLLRAQLGILVSQHSGVEAHSHSYSHSSSSLSEEPELSGGPPHITSSAPELRQRLTHVDSPLEAPAGPLGQVKLTLWYYSEERKLVSIVHGCRSLRQNGRDPPDPYVSLLLLPDKNRGTKRRTSQKKRTLSPEFNERFEWELPLDEAQRRKLDVSVKSNSSFMSRERELLGKVQLDLAETDLSQGVARWYDLMDNKDKGSS

ESYT1

Extended synaptotagmin-1

1104 amino acids

Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. Helps tether the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane (By similarity).

Belongs to the extended synaptotagmin family.

122.544 kDa

MERSPGEGPSPSPTDQPSAPSDPTGQPPAAHAKPDPGSGGQPAGPGAAGEALAVLTSFGKRLLVLIPVYLAGAVGLSVGFVLFGLALYLGWRRVRDEKERSLRAARQLLDDEEQLTAKTLYMSHRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYMEKLLAETVAPAVRGSNPHLQTFTFTRVELGEKPLRIIGVKVHPGQRKEQILLDLNISYVGDVQIDVEVKKYFCKAGVKGMQLHGVLRVILEPLIGDLPIVGAVSMFFIRRPTLDINWTGMTNLLDIPGLSSLSDTMIMDSIAAFLVLPNRLLVPLVPDLQDVAQLRSPLPRGIIRIHLLAARGLTSKDKYVKGLIEGKSDPYALVRLGTQTFCSRVIDEELNPQWGETYEVMVHEVPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQAGVLDDWFPLQGGQGQVHLRLEWLSLLSDAEKLEQVLQWNQGVSSRPEPPSAAILVVYLDRAQDLPLKKGNKEPNPMVQLSIQDVTQESKAVYSTNCPVWEEAFRFFLQDPQSQELDVQVKDDSRALTLGALTLPLARLLTAPELILDQWFQLSSSGPNSRLYMKLVMRILYLDSSEICFPTVPGCPGAWDVDSENPQRGSSVDAPPRPCHTTPDSQFGTEHVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKLAGRSFRSHVVREDLNPRWNEVFEVIVTSVPGQELEVEVFDKDLDKDDFLGRCKVSLTTVLNSGFLDEWLTLEDVPSGRLHLRLERLTPRPTAAELEEVLQVNSLIQTQKSAELAAALLSIYMERAEDLPLRKGTKHPSPYATLTVGDTSHKTKTVSQTSAPVWDESASFLIRKPHTENLELQVRGEGTGVLGSLSLPLSELLVADQLCLDRWFTLNSGQGQVLLRAQLGILVSQHSGVEAHSHSYSHSSSSLSEEPELSGGPPHVTSSAPELRQRLTHVDSSLEAPAGPLGQVKLTVWYYSEERKLVSIVHGCRALRQNGRDPPDPYVSLLLLPDKNRGTKRKTSQKKRTLSPEFNERFEWELPLDEAQRRKLDVSVKSNPSFMSRERELLGKVQLDLAETDLSQGVARWYDLMDDKDKGSS

Esyt1

Extended synaptotagmin-1

1092 amino acids

Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. Helps tether the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane (By similarity).

Belongs to the extended synaptotagmin family.

121.554 kDa

MEHSPEEGASPEPSGQPPATDSTRDGGSGVPPAGPGAASEALAVLTSFGRRLLVLVPVYLAGAAGLSVGFVLFGLALYLGWRRVRDGKERSLRAARQLLDDEERITAETLYMSHRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYMEKLLAETVAPAVRGANPHLQTFTFTRVELGEKPLRIIGVKVHPSQRKDQILLDLNVSYVGDVQIDVEVKKYFCKAGVKGMQLHGVLRVILEPLTGDLPIVGAVSMFFIKRPTLDINWTGMTNLLDIPGLSSLSDTMIMDSIAAFLVLPNRLLVPLVPDLQDVAQLRSPLPRGIIRIHLLAARGLSSKDKYVKGLIEGKSDPYALVRVGTQTFCSRVIDEELNPHWGETYEVIVHEVPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQAGVLDNWYPLQGGQGQVHLRLEWLSLLPDAEKLDQVLQWNRGITSRPEPPSAAILVVYLDRAQDLPLKKGNKEPNPMVQLSVQDVTRESKATYSTNSPVWEEAFRFFLQDPRSQELDVQVKDDSRALTLGALTLPLARLLTASELTLDQWFQLSSSGPNSRLYMKLVMRILYLDYSEIRFPTVPGAQDWDRESLETGSSVDAPPRPYHTTPNSHFGTENVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKVAGKSFRTHVVREDLNPRWNEVFEVIVTSIPGQELEIEVFDKDLDKDDFLGRYKVSLTTVLNSGFLDEWLTLEDVPSGRLHLRLERLTPRPTAAELEEVLQVNSLIQTQKSSELAAALLSVFLERAEDLPLRKGTKPPSPYATITVGETSHKTKTVSQSSAPVWEESASFLIRKPHAESLELQVRGEGTGTLGSVSLPLSELLQEDQLCLDHWFALSGQGQVLMRAQLGILVSQHSGVEAHSHSYSHSHSSSSLNDEPEALGGPTHPASPVLEVRHRLTHGDSPSEAPVGPLGQVKLTVWYHSDEQKLISIIHSCRALRQNGRDLPDPYVSVLLLPDKNRSTKRKTPQKKRTLNPEFNERFEWDLPLDGTLRRKLDVSVKSNSSFMSRERELLGKVQLDLAEIDLSQGAAQWYDLMDDRDKGGS

Esyt1

Extended synaptotagmin-1

1088 amino acids

Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. Helps tether the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane (By similarity).

Belongs to the extended synaptotagmin family.

121.159 kDa

MERSPEEGAGPEPSGQSPATDSTRERDGGSGVPPAGPGAASEALAVLTSFGRRLLVLVPVYLAGAAGLSVGFVLFGLALYLGWRRVRDGKERSLRAARQLLDDEERITAETLYMSHRELPAWVSFPDVEKAEWLNKIVVQVWPFLGQYMEKLLAETVAPAVRGANPHLQTFTFTRVELGEKPVRIIGVKVHPSQRKDQILLDLNVSYVGDLQIDVEVKKYFCKAGVKGMQLHGVLRVILEPLIGDLPIVGAVSMFFIKRPTLDINWTGMTNLLDIPGLSSLSDTMIMDSIAAFLVLPNRLLVPLVPDLQDVAQLRSPLPRGIIRIHLLAARGLSSKDKYVKGLIEGKSDPYALVRVGTQTFCSRVIDEELNPHWGETYEVIVHEVPGQEIEVEVFDKDPDKDDFLGRMKLDVGKVLQAGVLDNWYPLQGGQGQVHLRLEWLSLLPDAEKLDQVLQWNRGITSRPEPPSAAILVVYLDRAQDLPLKKGNKEPNPMVQLSVQDVTQESKATYSTNCPVWEEAFRFFLQDPRSQELDVQVKDDSRALTLGALTLPLARLLTASELTLDQWFQLSSSGPNSRLYMKLVMRILYLDSSEMRLPTEPGAQDWDSESPETGSSVDAPPRPYHTTPNSHFGTENVLRIHVLEAQDLIAKDRFLGGLVKGKSDPYVKLKVAGRSLRTHVVREDLNPRWNEVFEVIVTSIPGQELDIEVFDKDLDKDDFLGRYKVGLTTVLNSGFLDEWLTLEDVPSGRLHLRLERLSPRPTAAELEEVLQVNSLIQTQKSSELAAALLSVYLERSEDLPLRKGTKPPSPYAILTVGETSHKTKTVSQTSAPIWEESASFLIRKPHAESLELQVRGEGTGTLGSISLPLSELLQEEQLCLDRWFALSGQGQVLMRVQLGILVSQHSGVEAHSHSSSSLNEEPEVLGDPTHTASPVLEVRHRLTHGDSPSEALIGPLGQVKLTVWYHSDEQKLISIIHSCRALRQNGRDLPDPYVSVLLLPDKNRGTKRKTSQKKRTLNPEFNERFEWDLPLDGTLRRKLDVSVKSNSSFMSRERELLGKVQLDLAEIDLSQGAAQWYDLIDDRDKGGS