ERG10

Gene

ERG10

Protein

Acetyl-CoA acetyltransferase

Organism

Saccharomyces pastorianus (strain ATCC 76670 / Carlsberg bottom yeast no.2 / CBS 1503 / CLIB 180 / NBRC 10610 / NRRL Y-1525)

Length

398 amino acids

Function

Catalyzes the formation of acetoacetyl-CoA in the biosynthesis of mevalonate, an intermediate required for the biosynthesis of sterols and nonsterol isoprenoids.

Similarity

Belongs to the thiolase-like superfamily. Thiolase family.

Mass

41.659 kDa

Sequence

MSQNVYIVSTARTPIGSFQGSLSSKTAVELGAAALKGALAKVPELDASKDFDEIIFGNVLSANLGQAPARQVALTAGLGNHIVATTVNKVCASAMKAIILGAQSIKCGNADVVVAGGCESMTNAPYYMPAARGGAKFGQTVLIDGVERDGLNDAYDGLAMGVHAEKCARDWDITRDQQDSFAIESYQKSQQSQKEGKFDNEIVPVTIKGFRGKPDTQVTNDEEPARLHVEKLKSARTVFQRENGTVTAANASPINDGAAAIILVSERVLKEKNLKPLAIVKGWGEAAHLPADFTWAPSLAVPKALKHAGIEDINSVDYFEFNEAFSVVGLVNTKILKLDPSKVNVYGGAVALGHPLGCSGARVVVTLLSILQQEGGKIGVAAICNGGGGASSVVIEKL

Protein

Acetyl-CoA acetyltransferase: ERG10

Gene

ERG10

Protein

Acetyl-CoA acetyltransferase

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

398 amino acids

Function

Catalyzes the formation of acetoacetyl-CoA in the biosynthesis of mevalonate, an intermediate required for the biosynthesis of sterols and nonsterol isoprenoids.

Similarity

Belongs to the thiolase-like superfamily. Thiolase family.

Mass

41.729 kDa

Sequence

MSQNVYIVSTARTPIGSFQGSLSSKTAVELGAVALKGALAKVPELDASKDFDEIIFGNVLSANLGQAPARQVALAAGLSNHIVASTVNKVCASAMKAIILGAQSIKCGNADVVVAGGCESMTNAPYYMPAARAGAKFGQTVLVDGVERDGLNDAYDGLAMGVHAEKCARDWDITREQQDNFAIESYQKSQKSQKEGKFDNEIVPVTIKGFRGKPDTQVTKDEEPARLHVEKLRSARTVFQKENGTVTAANASPINDGAAAVILVSEKVLKEKNLKPLAIIKGWGEAAHQPADFTWAPSLAVPKALKHAGIEDINSVDYFEFNEAFSVVGLVNTKILKLDPSKVNVYGGAVALGHPLGCSGARVVVTLLSILQQEGGKIGVAAICNGGGGASSIVIEKI

Protein

Acetyl-CoA acetyltransferase: ERG10

Gene

erg10

Protein

Acetyl-CoA acetyltransferase

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

Length

395 amino acids

Function

Catalyzes the formation of acetoacetyl-CoA in the biosynthesis of mevalonate, an intermediate required for the biosynthesis of sterols and nonsterol isoprenoids.

Similarity

Belongs to the thiolase-like superfamily. Thiolase family.

Mass

40.998 kDa

Sequence

MVNTEVYIVSAVRTPMGSFGGSFASLPATKLGSIAIKGALERVNIKPSDVDEVFMGNVVSANLGQNPARQCALGAGLPRSIVCTTVNKVCASGMKATILGAQTIMTGNAEIVVAGGTESMSNAPYYAPKNRFGAKYGNVELVDGLLRDGLSDAYDGLPMGNAAELCAEEHSIDRASQDAFAISSYKRAQNAQATKAFEQEIVPVEVPVGRGKPNKLVTEDEEPKNLNEDKLKSVRAVFKSNGTVTAANASTLNDGASALVLMSAAKVKELGLKPLAKIIGWGEAAQDPERFTTSPSLAIPKALKHAGIEASQVDYYEINEAFSVVAVANTKILGLDPERVNINGGGVAMGHPLGSSGSRIICTLAYILAQKDAKIGVAAVCNGGGGASSIVIERV

Protein

Acetyl-CoA acetyltransferase: erg10