About Products Protein Database Contact

EPCAM

Gene
Epcam
Protein
Epithelial cell adhesion molecule
Organism
Mus musculus
Length
315 amino acids
Function
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity).
Similarity
Belongs to the EPCAM family.
Mass
35.019 kDa
Sequence
MAGPQALAFGLLLAVVTATLAAAQRDCVCDNYKLATSCSLNEYGECQCTSYGTQNTVICSKLASKCLAMKAEMTHSKSGRRIKPEGAIQNNDGLYDPDCDEQGLFKAKQCNGTATCWCVNTAGVRRTDKDTEITCSERVRTYWIIIELKHKERESPYDHQSLQTALQEAFTSRYKLNQKFIKNIMYENNVITIDLMQNSSQKTQDDVDIADVAYYFEKDVKGESLFHSSKSMDLRVNGEPLDLDPGQTLIYYVDEKAPEFSMQGLTAGIIAVIVVVSLAVIAGIVVLVISTRKKSAKYEKAEIKEMGEIHRELNA

Gene
Epcam
Protein
Epithelial cell adhesion molecule
Organism
Rattus norvegicus
Length
315 amino acids
Function
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity).
Similarity
Belongs to the EPCAM family.
Mass
35.207 kDa
Sequence
MAPPKALAFGLLLAVVTATLAAAQKDCVCNNYKLTSRCYENENGECQCTSYGTQNTVICSKLASKCLVMKAEMTHSKSGRRMKPEGAIQNNDGLYDPECDEQGLFKAKQCNGTATCWCVNTAGVRRTDKDTEITCSERVRTYWIIIELKHKERAQPYNFESLHTALQDTFASRYMLNPKFIKSIMYENNVITIDLMQNSSQKTQDDVDIADVAYYFEKDVKGESLFHSSKSMDLRVNGELLDLDPGQTLIYYVDEKAPEFSMQGLTAGIIAVIVVVVLAVIAGIVVLVISTRKRSAKYEKAEIKEMGEIHRELNA

Gene
EPCAM
Protein
Epithelial cell adhesion molecule
Organism
Bos taurus
Length
314 amino acids
Function
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity).
Similarity
Belongs to the EPCAM family.
Mass
34.859 kDa
Sequence
MAPPQVLAFGLLVAAATAAVAADQEGCVCENYKLTTNCSVNALGQCQCTSVGTQHSVICTKLATKCLVMKAEMNHSKSGRRGKPEGAIQNNDGLYDPECDDKGLFKAKQCNGTSTCWCVNTAGVRRTDKDSEISCSEPVRTYWIIIELKHKTREKPYDLQSLQSALKDVITNRYQLDPKYITNILYENDVITIDLVQNSSQKTQNDVDIADVAYYFEKDVKDESLFHSKRMDLRVNGELLDLDPGRTSIYYVDEKPPEFSMQGLQAGIIAVIVVVVVAIIAGIIVLVVSRKKSMTKYEKAEIKEMGEMHRELNA

Gene
EPCAM
Protein
Epithelial cell adhesion molecule
Organism
Homo sapiens
Length
314 amino acids
Function
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
Similarity
Belongs to the EPCAM family.
Mass
34.932 kDa
Sequence
MAPPQVLAFGLLLAAATATFAAAQEECVCENYKLAVNCFVNNNRQCQCTSVGAQNTVICSKLAAKCLVMKAEMNGSKLGRRAKPEGALQNNDGLYDPDCDESGLFKAKQCNGTSMCWCVNTAGVRRTDKDTEITCSERVRTYWIIIELKHKAREKPYDSKSLRTALQKEITTRYQLDPKFITSILYENNVITIDLVQNSSQKTQNDVDIADVAYYFEKDVKGESLFHSKKMDLTVNGEQLDLDPGQTLIYYVDEKAPEFSMQGLKAGVIAVIVVVVIAVVAGIVVLVISRKKRMAKYEKAEIKEMGEMHRELNA

Gene
EPCAM
Protein
Epithelial cell adhesion molecule
Organism
Gallus gallus
Length
306 amino acids
Similarity
Belongs to the EPCAM family.
Mass
34.36 kDa
Sequence
MELLRGAALLLLLCAAACAQDSCTCTKNKRVTNCRLIDNVCHCNSIGSSVPVNCEILTSKCLLMKAEMANTKSGRREKPKDALQDTDGLYDPECENNGLFKAKQCNGTTCWCVNTAGVRRTDKHDTDLKCNQLVRTTWIIIEMRHAERKTPLNAESLTRYLKDTITSRYMLDGRYISGVVYENPTITIDLKQNSSDKTPGDVDITDVAYYFEKDVKDDSIFLNNKLNMNIDNEELKFDNMMVYYVDEVPPEFSMKSLTAGVIAVIVIVVLAIVAGIIGLVLSRRRKGKYVKAEMKEMNEMHRGLNA