About Products Protein Database Contact

ECU06_0720

Gene
ECU06_0720
Protein
Serine/threonine-protein phosphatase 2A activator
Organism
Encephalitozoon cuniculi (strain GB-M1)
Length
247 amino acids
Function
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).
Similarity
Belongs to the PTPA-type PPIase family.
Mass
28.843 kDa
Sequence
MKNGIDFVETEAYARIYNFILMVDDSIKNSEQRQSKHHMDVLADITRIVSETEKDPSPQRYANMAAKTVFKKIYDTYDDEYLRNSFGNQIRLDYGTGHELNFLCYLYAQYCRGSIGIDCVFTILVKYFEIVRLFITKFNLEPAGSHGMWGLDDYQFLPFLFGSSELCNTTLRFDELDGSKCYFVAVEKKLGGSSRILKSIMDKDWASINRGMIRMYDDHVLRRSVVTQHFIYGEYLRKDRSQANKDL