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ECU01_0700

Gene
ECU01_0700
Protein
Eukaryotic translation initiation factor 2 subunit gamma
Organism
Encephalitozoon cuniculi (strain GB-M1)
Length
439 amino acids
Function
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B (By similarity).
Similarity
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
Mass
47.773 kDa
Sequence
MNDALEIMKKQATLNIGTIGHVAHGKSTIVKAISGISTIKFKAELERNITIKLGYANAKIYKCDSKCVRPNCYQSFGSSSPDRLSCKKCGGTLKLVRHVSFVDCPGHDVLMATMLNGTAIMDAVLLLIAANEPCPQPQTTEHLFAVEIMDLKKVLVVQNKIDLVSREQALEQHDQIQKFLKTSNVSGPVIPTAAQIGVNIPALLDFIVNYIPEPVRDSTARPKMIVIRSFDVNRPGTRVCEMSGGVIGGSLVTGMLRVGDKIEIRPGLVIRKGNRFVCRPFVSEIVSLKAESIDLSEAYPGGLIGVGTTMDPSFCKADKLVGQVMGKLGFLPSIFHKITVEYSLFPKTTIQGSSKLKEGEHVLLNIGSTTTGSVIGRINETSGEFDLVKPACCEIGERIAISRKINNHWRLIGHGEIKDGTCIEPEYDAEIDDAQRKAD

Gene
ECU01_0700
Protein
Eukaryotic translation initiation factor 2 subunit gamma
Organism
Encephalitozoon cuniculi (strain GB-M1)
Length
439 amino acids
Function
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B (By similarity).
Similarity
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
Mass
47.773 kDa
Sequence
MNDALEIMKKQATLNIGTIGHVAHGKSTIVKAISGISTIKFKAELERNITIKLGYANAKIYKCDSKCVRPNCYQSFGSSSPDRLSCKKCGGTLKLVRHVSFVDCPGHDVLMATMLNGTAIMDAVLLLIAANEPCPQPQTTEHLFAVEIMDLKKVLVVQNKIDLVSREQALEQHDQIQKFLKTSNVSGPVIPTAAQIGVNIPALLDFIVNYIPEPVRDSTARPKMIVIRSFDVNRPGTRVCEMSGGVIGGSLVTGMLRVGDKIEIRPGLVIRKGNRFVCRPFVSEIVSLKAESIDLSEAYPGGLIGVGTTMDPSFCKADKLVGQVMGKLGFLPSIFHKITVEYSLFPKTTIQGSSKLKEGEHVLLNIGSTTTGSVIGRINETSGEFDLVKPACCEIGERIAISRKINNHWRLIGHGEIKDGTCIEPEYDAEIDDAQRKAD