EBP1

Probable NADPH dehydrogenase

407 amino acids

Oxidoreductase that binds mammalian estrogens with high affinity.

Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

46.074 kDa

MTIESTNSFVVPSDTKLIDVTPLGSTKLFQPIKVGNNVLPQRIAYVPTTRFRASKDHIPSDLQLNYYNARSQYPGTLIITEATFASERGGIDLHVPGIYNDAQAKSWKKINEAIHGNGSFSSVQLWYLGRVANAKDLKDSGLPLIAPSAVYWDENSEKLAKEAGNELRALTEEEIDHIVEVEYPNAAKHALEAGFDYVEIHGAHGYLLDQFLNLASNKRTDKYGCGSIENRARLLLRVVDKLIEVVGANRLALRLSPWASFQGMEIEGEEIHSYILQQLQQRADNGQQLAYISLVEPRVTGIYDVSLKDQQGRSNEFAYKIWKGNFIRAGNYTYDAPEFKTLINDLKNDRSIIGFSRFFTSNPDLVEKLKLGKPLNYYNREEFYKYYNYGYNSYDESEKQVIGKPLA

EBP1

ERBB-3 BINDING PROTEIN 1

392 amino acids

Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly (By similarity). Required for expression of cell cycle genes such as CYCD3-1, RNR2A and CDKB1-1. Promotes, in a dose- and auxin-dependent manner, organ growth by stimulating both cell proliferation and expansion, via the regulation of RBR1 levels (PubMed:17024182).

Belongs to the peptidase M24 family.

42.979 kDa

MSSDDERDEKELSLTSPEVVTKYKSAAEIVNKALQVVLAECKPKAKIVDICEKGDSFIKEQTASMYKNSKKKIERGVAFPTCISVNNTVGHFSPLASDESVLEDGDMVKIDMGCHIDGFIALVGHTHVLQEGPLSGRKADVIAAANTAADVALRLVRPGKKNTDVTEAIQKVAAAYDCKIVEGVLSHQLKQHVIDGNKVVLSVSSPETTVDEVEFEENEVYAIDIVASTGDGKPKLLDEKQTTIYKKDESVNYQLKMKASRFIISEIKQNFPRMPFTARSLEEKRARLGLVECVNHGHLQPYPVLYEKPGDFVAQIKFTVLLMPNGSDRITSHTLQELPKKTIEDPEIKGWLALGIKKKKGGGKKKKAQKAGEKGEASTEAEPMDASSNAQE

EBP1

ERBB-3 BINDING PROTEIN 1

387 amino acids

Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly (By similarity). Required for expression of cell cycle genes such as CYCD3-1, RNR2A and CDKB1-1. Promotes, in a dose- and auxin-dependent manner, organ growth by stimulating both cell proliferation and expansion, via the regulation of RBR1 levels (PubMed:17024182).

Belongs to the peptidase M24 family.

42.74 kDa

MSDDEREEKELDLTSPEVVTKYKSAAEIVNKALQLVLSECKPKAKIVDLCEKGDAFIKEQTGNMYKNVKKKIERGVAFPTCISVNNTVCHFSPLASDETVVEEGDILKIDMGCHIDGFIAVVGHTHVLHEGPVTGRAADVIAATNTAAEVALRLVRPGKKNSDVTEAIQKVAAAYDCKIVEGVLSHQMKQFVIDGNKVVLSVSNPDTRVDEAEFEENEVYSIDIVTSTGDGKPKLLDEKQTTIYKRAVDKSYNLKMKASRFIFSEISQKFPIMPFTARDLEEKRARLGLVECVNHELLQPYPVLHEKPGDLVAHIKFTVLLMPNGSDRVTSHALQELQPTKTTENEPEIKAWLALPTKTKKKGGGKKKKGKKGDKVEEASQAEPMEG