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Dusp3

Gene
Dusp3
Protein
Dual specificity protein phosphatase 3
Organism
Mus musculus
Length
185 amino acids
Function
Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2 (By similarity).
Similarity
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Mass
20.472 kDa
Sequence
MSSSFELSVQDLNDLLSDGSGCYSLPSQPCNEVVPRVYVGNASVAQDITQLQKLGITHVLNAAEGRSFMHVNTSASFYEDSGITYLGIKANDTQEFNLSAYFERATDFIDQALAHKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSTVRQNREIGPNDGFLAQLCQLNDRLAKEGKVKL

Gene
DUSP3
Protein
Dual specificity protein phosphatase 3
Organism
Pongo abelii
Length
185 amino acids
Function
Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2 (By similarity).
Similarity
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Mass
20.478 kDa
Sequence
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP