Dio1

Type I iodothyronine deiodinase

257 amino acids

Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine).

Belongs to the iodothyronine deiodinase family.

29.568 kDa

MGLPQLWLWLKRLVIFLQVALEVAVGKVLMTLFPGRVKQSILAMGQKTGMARNPRFAPDNWVPTFFSIQYFWFVLKVRWQRLEDRAEFGGLAPNCTVVCLSGQKCNIWDFIQGSRPLVLNFGSCTUPSFLLKFDQFKRLVDDFASTADFLIIYIEEAHATDGWAFKNNVDIRQHRSLQERVRAARLLLARSPQCPVVVDTMQNQSSQLYAALPERLYVIQEGRICYKGKAGPWNYNPEEVRAVLEKLCTPPRHVPQL

Dio1

Type I iodothyronine deiodinase

257 amino acids

Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine).

Belongs to the iodothyronine deiodinase family.

29.73 kDa

MGLSQLWLWLKRLVIFLQVALEVATGKVLMTLFPERVKQNILAMGQKTGMTRNPRFAPDNWVPTFFSIQYFWFVLKVRWQRLEDRAEYGGLAPNCTVVRLSGQKCNVWDFIQGSRPLVLNFGSCTUPSFLLKFDQFKRLVDDFASTADFLIIYIEEAHATDGWAFKNNVDIRQHRSLQDRLRAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYVIQEGRICYKGKPGPWNYNPEEVRAVLEKLCIPPGHMPQF

DIO1

Type I iodothyronine deiodinase

257 amino acids

Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine).

Belongs to the iodothyronine deiodinase family.

29.454 kDa

MGLPGLGLLLKRFGVLVRVALKVAVGKVLLTLWPSAIRPHLLAMSEKTGMAKNPRFTYEDWAPTFFSTQYFWFVLKVNWQQLEDRTKQGDIAPDSPVVHLSGQRARLWDFMQGNRPLVLNFGSCSUPSFLFKFDQFKRLVEDFSSVADFLTVYIEEAHASDGWAFKNNVDIRRHRDLQERLQAARLLLDRNPGCPVVVDTMENRSSQLYAALPERLYVLQEGRILYKGGPGPWNYHPEEVHAVLEQLCRSSAQSPRL

dio1

Type I iodothyronine deiodinase

252 amino acids

Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine).

Belongs to the iodothyronine deiodinase family.

29.187 kDa

MESLLQTIKLMLRYIQKALILFFLFLYVVVGKVLMFLFPQTMASVLKSRFEISGVHDPKFQYEDWGPTFFTYKFLRSVLEIMWMRLEDEAFVGHSAPNTPVVDLSGELHHIWDYLQGTRPLVLSFGSCTUPPFLFRLGEFNKLVNEFNSIADFLIIYIDEAHAADEWALKNNLHIKKHRSLQDRLAAAKRLMEESPSCPVVLDTMSNLCSAKYAALPERLYILQEGKIIYKGKMGPWGYKPEEVCSVLEKKK

DIO1

Type I iodothyronine deiodinase

249 amino acids

Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine).

Belongs to the iodothyronine deiodinase family.

28.888 kDa

MELPLPGLWLKRLWVLFQVALHVAMGKVLMTLFPGRVKQDILAMSQKTGMAKNPHFSHENWIPTFFSAQYFWFVLKVRWQRLEDKTEEGGLAPNCPVVSLSGQRCHIWDFMQGNRPLVLNFGSCTUPSFIFKFDQFKRLIEDFSSIADFLIIYIEEAHASDGWAFKNNVDIKNHQNLQDRLRAAHLLLDRSPQCPVVVDTMKNQSSRLYAALPERLYVLQAGRILYKGKPGPWNYHPEEVRAVLEKLHS

DIO1

Type I iodothyronine deiodinase

249 amino acids

Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine).

Belongs to the iodothyronine deiodinase family.

28.526 kDa

MGLPRPGLWLKRLWVLVQVAVEVAVGKVLMTLFPERVKQNILAMGQKTGIAQNPNFAQDSWIPTFFSTQYFWFVLKVRWQRLEDATEPGGLAPNCSVVRLSGQQCSVWDFMRGNRPLVLNFGSCTUPSFLSKFDQFKRLIQDFSSIADFLIIYIEEAHASDGWAFKNNVDIKNHRNLQDRLRAASLLLARSPQCPVVVDTMQNQSSQLYAALPERLYVLRQGRILYKGESGPWNYNPEEVRAVLEELHS

DIO1

Type I iodothyronine deiodinase

249 amino acids

Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.

Belongs to the iodothyronine deiodinase family.

28.924 kDa

MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDNWIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQGNRPLVLNFGSCTUPSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASDGWAFKNNMDIRNHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKGKSGPWNYNPEEVRAVLEKLHS

dio1

Type I iodothyronine deiodinase

248 amino acids

Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine).

Belongs to the iodothyronine deiodinase family.

28.21 kDa

MFLQKIVLYLSTACMFCYMLGKFLMLVILQFFSPSLAKKFILRMGEKITMTQNPRFNYEDWGLTFMSLAFIKTASSHMWLSLGEEAFVGGEAPDSPVVTMDREKTSISKYLKGNRPLVLSFGSCTUPPFMYKLDEFKQLVKDFSDVADFLVIYIAEAHSTDGWAFKNNYDINQHQSLEDRLSAAQVLVQSEPLCPVVVDEMTDVTTIKYGALPERLFILQAGKVLYKGGKGPWGYNPAEVRSFLEKIK

dio1

Type I iodothyronine deiodinase

248 amino acids

Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine).

Belongs to the iodothyronine deiodinase family.

27.849 kDa

MFLQKLLVYLTAACMFCYILVLSATLNVLKVLSPNLARKLILKMGEKVTMTQNPKFSYEDWGLTYGSLAFIKVASQTMWLSLGQEAFVGEDAPDSPVVTVDGERTSICNYLKGNRPLVLSFGSCTUPPFMFKLGEFKQLVRDFVDVADFLVVYVAEAHSTDGWSFGNNFDIRQHRSLEDRLSAARILVQNDPLCPVVVDEMSNVSAIKYAAQPERLYVLQAGKVLYKGAMGPWGYNPQEVRSVLQKMR

DIO1

Type I iodothyronine deiodinase

245 amino acids

Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine).

Belongs to the iodothyronine deiodinase family.

28.386 kDa

single

LSIRVLLHKLLILLQVTLSVVVGKTMMILFPDTTKRYILKLGEKSRMNQNPKFSYENWGPTFFSFQYLLFVLKVKWRRLEDEAHEGRPAPNTPVVALNGEMQHLFSFMRDNRPLILNFGSCTUPSFMLKFDEFNKLVKDFSSIADFLIIYIEEAHAVDGWAFRNNVVIKNHRSLEDRKTAAQFLQQKNPLCPVVLDTMENLSSSKYAALPERLYILQAGNVIYKGGVGPWNYHPQEIRAVLEKLK

DIO1

Type I iodothyronine deiodinase

244 amino acids

Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.

Belongs to the iodothyronine deiodinase family.

28.424 kDa

MGLPRPVLWLRRLWVLLQVAVQVAVGKVFLKLFPARVKQHIVAMNGKNPHFSYDNWAPTLYSMQYFWFVLKVQWQRLEDRTEPGGLAPNCPVVRLSGQRCNIWDFMQGNRPLVLNFGSCTUPSFLFKFDQFKRLIEDFCSTADFLIIYIEEAHASDGWAFKNNVNIRTHQTLQDRLQAARLLLDRAPPCPVVVDTMRNQSSQFYAALPERLFVLQEGRILYKGKPGPWNYHPEEVRAVLEKLHS

DIO1

Type I iodothyronine deiodinase

244 amino acids

Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.

Belongs to the iodothyronine deiodinase family.

28.489 kDa

MGLSQLGLWLRRLWVLFQVALQVAVGKVFLILFPSRVKQHIVAMNRKNPHFSYDNWAPTLYSVQYFWFVLKVRWQRLEDRTEPGGLAPNCPVVRLSGQRCSIWDFMKGNRPLVLNFGSCTUPSFLFKFDQFKRLIEDFCSIADFLIIYIEEAHASDGWAFKNNVNIRNHRNLQDRLQAACLLLDRSPRCPVVVDTMKNQSSRLYAALPERLYVLQAGRILYKGKPGPWNYHPEEVRAVLEKLHS