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Daro_3096

Gene
Daro_3096
Protein
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase
Organism
Dechloromonas aromatica (strain RCB)
Length
163 amino acids
Function
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
Similarity
Belongs to the class II aldolase/RraA-like family.
Mass
17.451 kDa
Sequence
MTFKTPDLCDEFESELGKTVRVVTPMFQRYGGRTSFSGQIVTLKIFEDNSLVREVFGEDGKGKVLVIDGGGSLRCALVGDQLAILANKNGWEGVVVYGCIRDSGDINGIDIGVRALNTHPQKTLKKGVGDKNVAVTFGGVTFNPGEYLYADEDGVLVSGKALT