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DRC4

Gene
DRC4
Protein
Dynein regulatory complex subunit 4
Organism
Chlamydomonas reinhardtii
Length
471 amino acids
Function
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (PubMed:12847082, PubMed:23427265, PubMed:25411337). Plays an important role in the assembly of the N-DRC linker (PubMed:23427265).
Similarity
Belongs to the DRC4 family.
Mass
55.108 kDa
Sequence
MAPKKKGTKKESKKDAVATGDIEGASVEELNQKIGTLEKEKNKEEEYRNYMQLERDKINAFWEITKKDLEDRRAELRNKDREMEEMEERHQVEIKVYKQKVKHLLYEHQNNITTLKSDGELALKLQQDEYRKREGDLGKDKRNLKLELKEQELAHQDIIRQLKLEHAKEITKLRQEFEQQAKDLQSKYEKKMKMLRDDMELRRKQEIHEIEERKNTHINELMKKHERAFAEIKNYYNDITHNNLDLIKTLKEDVAEMKRREAANEKLMYEIAQDNKKLSEPLSRALKEVELLRQQLANYDKDKLSLAQTKARLLNAERQIKNLEWENEVLSQRFSKVQTERDELYGKFEASIYDVQQKTGLKSALLEKKVEALGEALEMKEAQLAEVLTAANLDPGTLAAINQRLEEVLDNKNQIIKALQYDVAKVSKAHNDLIRVYEAKLTEFGIPVDELGFRPLVTNTSTGPAGLVVGA