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DRAM1

Gene
dram1
Protein
DNA damage-regulated autophagy modulator protein 1
Organism
Xenopus laevis
Length
239 amino acids
Function
Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis.
Similarity
Belongs to the DRAM/TMEM150 family.
Mass
26.622 kDa
Sequence
MHCWCLQGAAFLPSILVIWSSAGFLFSYIISVLIGHVPPFVPYISDTGTSPPESGVFGFMISVSAMLGAATMYTRYMILERQNLSIDFLPIYFNKISLAIGLFGCIGMGIVATFQEMAVPAVHDAGALITFICGVMYILLQSYISYKSCPTWNTRATCHIRMTVSLIAFIAVVPMSVFSILSGRKRLDWKPSDEGYPYHLTSAICEWTVAFGFNMYFLTFIRDFQGVSIQISTEIHEDF

Gene
dram1
Protein
DNA damage-regulated autophagy modulator protein 1
Organism
Xenopus tropicalis
Length
239 amino acids
Function
Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis.
Similarity
Belongs to the DRAM/TMEM150 family.
Mass
26.578 kDa
Sequence
MPCWCLHGAAFLPSILVIWSSAGFLFSYIISVLIGHVPPFVPYISDTGTSPPESGVFGFMISLSAMLGAATMYTRYKILEKQNHSTDFLPYYFNKTSLAIGLLGCIGMGIVATFQEMAVPAVHDAGALITFICGVLYILLQSYISYKSCPAWNTRVTCHIRMAISVIAFIAVVPMSVFSVLSGRKRLDWKPSDEGYHYHLTSAICEWIVAFGFNMYFLTFIRDFQGVSIQISTEIHEDF

Gene
DRAM1
Protein
DNA damage-regulated autophagy modulator protein 1
Organism
Homo sapiens
Length
238 amino acids
Function
Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy.
Similarity
Belongs to the DRAM/TMEM150 family.
Mass
26.253 kDa
Sequence
MLCFLRGMAFVPFLLVTWSSAAFIISYVVAVLSGHVNPFLPYISDTGTTPPESGIFGFMINFSAFLGAATMYTRYKIVQKQNQTCYFSTPVFNLVSLVLGLVGCFGMGIVANFQELAVPVVHDGGALLAFVCGVVYTLLQSIISYKSCPQWNSLSTCHIRMVISAVSCAAVIPMIVCASLISITKLEWNPREKDYVYHVVSAICEWTVAFGFIFYFLTFIQDFQSVTLRISTEINGDI

Gene
Dram1
Protein
DNA damage-regulated autophagy modulator protein 1
Organism
Mus musculus
Length
238 amino acids
Function
Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy (By similarity).
Similarity
Belongs to the DRAM/TMEM150 family.
Mass
26.201 kDa
Sequence
MLCFLRGMAFVPFLLVTWSSAAFIISYVVAVLSGHVNPFLPYISDTGTTPPESGIFGFMINFSAFLGAATMYTRYKIVEKQNETCYFSTPVFNLVSLALGLVGCIGMGIVANFQELAVPVVHDGGALLAFVCGVVYTLLQSIISYKSCPQWNSLTTCHVRMAISAVSCAAVVPMIACASLISITKLEWNPKEKDYIYHVVSAICEWTVAFGFIFYFLTFIQDFQSVTLRISTEINDDF