dpp7

Dipeptidyl-peptidase 7

818 amino acids

Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. Most efficiently cleaves the synthetic substrate Met-Leu-methylcoumaryl-7-amide (Met-Leu-MCA), and slowly hydrolyzes Leu-Gln-, Lys-Ala-, Leu-Arg, and Ala-Asn-MCA. Is likely involved in amino acid metabolism and bacterial growth/survival of asaccharolytic P.endodontalis, that utilizes amino acids from extracellular proteinaceous nutrients as energy and carbon sources.

Belongs to the peptidase S46 family.

91.085 kDa

MKLKRILLSVALLCGIGTTAMADKGMWLLNELNQQNYERMKELGFKLSPEQLYSLGQPSVASAVVIFGGGCTGITVSNEGLIFTNHHCGFGAIQSQSTVDHDYLRDGFRSNNHVEELPIPGLSVRYLREIVDVTPRIEAAVKGAKSEMERMQIIEELSQKINAEYTKGSTVVGEVTPYYAGNKYYVVVYNVFQDVRLVMAPPSSVGKFGGDTDNWMWTRHTGDFSVFRVYADANNNPALYSQNNKPYKPISYAPVSLNGYREGDYAMTIGFPGSTNRYLTSWGVEDVVNNENSPRIEVRGIKQAIWKEAMEADQATRIKYASKYAQSSNYWKNSIGMNRGLKNLDVVNRKRAEEKAFEAWIAKNNSQSTYGHILPGLKADYAKSAAISKDINYLYETLWGGTEIVRLARDVNSVGRIQAADMPKYKGRLEELYKDYLPSLDVKVLPAMLDIVRQRVSADCQPDIFKFIDKKFKGSTEKYAQYVFEKSIVPYADKVKDFLNLPADKQKKILDKDPAVALFNSVLPAIMQAQDKSEEMMLNIEKGKREYFAASRIMDPNRQMPSDANFTMRMSYGSIKGYAPKDGAWYNYYTTEQGVFEKQDPTSSEFAVQPEILSLLRSKDFGQYGVGDHLRLCFLSDNDITGGNSGSPVFNGNGELIGLAFDGNWEAMSGDIEFEPDLQRTISVDIRYVLFMIDKWAKMPHLIKELNLVKGDQRDLMPAGKGGNCSHKKAQTCAKKECSKGKKCAEKSATCISAMKDGKPCKTEKACAAGQKSAEKKANCCSTMKDGKPCTGDKDCAKSGKACCGKNKEAAAKKASKK

dpp7

Dipeptidyl-peptidase 7

721 amino acids

Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. Most potently cleaves the synthetic substrate Met-Leu-methylcoumaryl-7-amide (Met-Leu-MCA), followed by Leu-Arg-, and to a much lesser extent Lys-Ala-, Leu-Asp-, Leu-Glu-, Leu-Lys, and Val-Arg-MCA, while this enzyme does not hydrolyze Gly-Arg-, Gly-Gly-, Lys-Lys-, or Gly-Pro-MCA.

Belongs to the peptidase S46 family.

81.134 kDa

MNRLKLYLLALTALAVCSAKADEGMWLLQLMQQQHSIDMMKKQGLKLEAQDLYNPNGVSLKDAVGIFGGGCTGEIISPEGLILTNHHCGYASIQQHSSVEHDYLTDGFWATSRDKELPTPGLKFTFIERIEDITDIVNLRIAAKEITESESFSSTFLNKLAKELFEKSDLKGKKGIVPQALPFYAGNKFYMFYKKVYPDVRMVAAPPSSIGKFGGETDNWMWPRHTGDFSMFRIYADANGEPAEYSASNVPLKTKKHLNISIKGLKEGDYAMIMGFPGSTSRYLTVSEVKERMEASNAPRIRIRGTRQDVLKEAMNASDKVRIQYANKYAGSSNYWKNSIGMNKAIIDNNVLGTKAEQEAKFAKFAKEKNNTDYMNVVAKIDEAVAKTSPIKYQQTCLTETFFGGIEFGSPFMVMDKLKEALEQKNDSSIEANIKVLKEVFNDIHNKDYDHEVDRKVAKALLPLYAEMIPAGQRPAIYDVIEKEYKGDYNAYVDAMYDTSILANQANFDKFIKKPTVKAIEKDIATQYSRAKFDKYTNLAEQMGKLPEELALLHKTYIRGLGEMKLPVPSYPDANFTIRLTYGNVKPYSPKDGVYYKYYTTTDGILEKENPEDREFVVPAKLKELIEKKDFGRYALPNGEMPVCFLSTNDITGGNSGSPVLNENGELIGCAFDGNWESLSGDINFDNNLQRCINLDIRYVLFILEKLGGCGHLINEMTIVE

dpp7

Dipeptidyl-peptidase 7

721 amino acids

Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. Most potently cleaves the synthetic substrate Met-Leu-methylcoumaryl-7-amide (Met-Leu-MCA), followed by Leu-Arg-MCA, while this enzyme does not hydrolyze Gly-Arg-, Gly-Gly-, Lys-Lys-, or Gly-Pro-MCA.

Belongs to the peptidase S46 family.

81.212 kDa

MKKFKLLLLALMCVAFLPSKADEGMWLLQLMQEQHLADRMKAQGLLLEADDIYNPNRVSLKDAVGIFGGGCTGEIISPDGLILTNHHCGYGAIQQHSSVEHDYLTDGFWAKSRKEELPTPGLKFKFVERIVDVTDKVNNKVKSGEVKEEETFEYDFLKKLADEELKASDLNGKAGISAQALPFYAGNKFYLIYLKTYSDVRMVAAPPSSIGKFGGETDNWMWPRHTCDFSVFRIYADANGEPAEYNENNVPLKAKKHLAISLKGINEGDYAMIMGFPGSTNRYLTQSEVKQRMHSTNEPRIRIRGVRQDVLKKEMAASDKVRIQYASKYAGSSNYWKNSIGMNKAIIDNKVLETKAEQEAKFAAFAKAKGNTDYEKVVSEIDAAIEKSNPILYNYTCFREVFQGGIEFGTPYLILDKLKDAIKNKDKEAINKNIETLKKVYADIHNKDYDHEVDRKVAKALLPLYAEMVPADALPAFYTTIQKDFKGNYDAYVDHCYDNSIFSNEANFNKFIKKPTVKAIEKDPMTAYVRAKYDLMDKLGNELAESMKGMDLLHKTYVRGLCEMYSPEPKAPDANFTIRLTYGNVKSYNPKDGVHYKYYTTLKGVMEKEDPTNPEFVVPAKLKELYEAKDFGRYALPNGDMPACFLTTNDITGGNSGSPVINGNGELIGAAFDGNWESLSGDINFDNNLQRCIAVDIRYVLFIIDKLGGCKHLIDEMTIVE

dpp7

Dipeptidyl-peptidase 7

715 amino acids

Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. Most potently cleaves the synthetic substrate Met-Leu-methylcoumaryl-7-amide (Met-Leu-MCA), followed by Lys-Ala-, Leu-Arg- > Leu-Asp-, Leu-Glu-, >Leu-Lys, and >Val-Arg-MCA, while this enzyme does not hydrolyze Gly-Arg-, Gly-Gly-, Lys-Lys-, or Gly-Pro-MCA.

Belongs to the peptidase S46 family.

82.061 kDa

MRKLIFSLVTSFFLLLPSVIRADEGMWFLMFIKRLNERDMQKKGLQLTAEEIYSINNNSLKNAIVQFNGGCTASIISPDGLVITNHHCGYGAIAGLSTPEHNYLKDGYWAKDRSQELPPKSLYVRFFVRMDNVTDRMLSVVNSSMSEKERQDALNREMEKIQKENSEGGKYVVSVRPFFQGNEYYYFVYQDFKDVRFVGTPPENVGKFGGDTDNWEWPRHTGDFSVFRVYTDKDGNPAPYSPNNIPMKAKKYLNVTLKGVQENDFAMILGYPGRTNRWVSSHWVDQQVKYGYPAWVEASKTAMDAMKAHMDKDKAVRLKYASRYASLANYWKNRQGMIDALTAHKTADLKRAAEKKFAVWANKPENKAEYGNVLSDLATYFEKTNQEAANHNYLLLFFRASRIVPQANGYVKQLNTYLNSSSDQEKQQIRERIAKELDAYYSESYLPAEIDLFADNLKLYADKATDIPQEIAQIKSQYNGDFRKFAAEVFARSIFTTKENFENFMNNPSSDALQSDPIAQIARVMIDKYYNSQSEALKDGYEKAFRKYVKGMRDSKVSLILYPDANSTLRLTYGSVKSLPKDKRNHDVKRNYYTTFKTMLEKYKPGDAEFDMPKKFVEMYEKKDFGRYLDKDGTMHVCFLTNNDITGGNSGSPVMNGKGELIGLAFDGNIEAMAGDVIFDKKLQRTIVVDIRYVLWCIDTFGGAKHIVDEMTIIQ

dpp7

Dipeptidyl-peptidase 7

712 amino acids

Catalyzes the removal of dipeptides from the N-terminus of oligopeptides (PubMed:11096098, PubMed:23246913). Shows a broad specificity for both aliphatic and aromatic residues in the P1 position, with glycine or proline being not acceptable in this position (PubMed:11096098). Most potently cleaves the synthetic substrate Met-Leu-methylcoumaryl-7-amide (Met-Leu-MCA), Leu-Arg-MCA and Lys-Ala-MCA to a lesser extent (PubMed:23246913). Is likely involved in amino acid metabolism and bacterial growth of asaccharolytic P.gingivalis, that utilizes amino acids from extracellular proteinaceous nutrients as energy and carbon sources (PubMed:11096098).

Belongs to the peptidase S46 family.

80.107 kDa

MQMKLKSILLGAALLLGASGVAKADKGMWLLNELNQENLDRMRELGFTLPLDSLYSFDKPSIANAVVIFGGGCTGITVSDQGLIFTNHHCGYGAIQSQSTVDHDYLRDGFVSRTMGEELPIPGLSVKYLRKIVKVTDKVEGQLKGITDEMERLRKAQEVCQELAKKENADENQLCIVEPFYSNNEYFLIVYDVFKDVRMVFAPPSSVGKFGGDTDNWMWPRHTGDFSVFRVYAGADNRPAEYSKDNKPYKPVYFAAVSMQGYKADDYAMTIGFPGSTDRYLTSWGVEDRIENENNPRIEVRGIKQGIWKEAMSADQATRIKYASKYAQSANYWKNSIGMNRGLARLDVIGRKRAEERAFADWIRKNGKSAVYGDVLSSLEKAYKEGAKANREMTYLSETLFGGTEVVRFAQFANALATNPDAHAGILKSLDDKYKDYLPSLDRKVLPAMLDIVRRRIPADKLPDIFKNVIDKKFKGDTKKYADFVFDKSVVPYSDKFHAMLKSMDKEKFAKAIEKDPAVELSKSVIAAARAIQADAMANAYAIEKGKRLFFAGLREMYPGRALPSDANFTMRMSYGSIKGYEPQDGAWYNYHTTGKGVLEKQDPKSDEFAVQENILDLFRTKNYGRYAENGQLHIAFLSNNDITGGNSGSPVFDKNGRLIGLAFDGNWEAMSGDIEFEPDLQRTISVDIRYVLFMIDKWGQCPRLIQELKLI

Dpp7

Dipeptidyl peptidase 2

506 amino acids

Plays an important role in the degradation of some oligopeptides.

Belongs to the peptidase S28 family.

56.254 kDa

MNFHPCYPVDHGVPSWILVLLLSLGLCNLQARADRVLDPDFHENYFEQYMDHFNFESFGNKTFGQRFLVSDKFWKMGEGPIFFYTGNEGDIWSFANNSGFMVELAAQQEALLVFAEHRYYGKSLPFGVQSTQRGYTQLLTVEQALADFAVLLQALRQDLGVHDAPTIAFGGSYGGMLSAYMRMKYPHLVAGALAASAPVVAVAGLGDSYQFFRDVTADFYGQSPKCAQAVRDAFQQIKDLFLQGAYDTISQNFGTCQSLSSPKDLTQLFGFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCQRLLNEGQRIMGLRALAGLVYNSSGTEPCYDIYRLYQSCADPTGCGTGSDARAWDYQACTEINLTFDSNNVTDMFPEIPFSEELRQQYCLDTWGVWPRQDWLQTSFWGGDLKAASNIIFSNGDLDPWAGGGIQSNLSTSVIAVTIQGGAHHLDLRASNSEDPPSVVEVRKLESTLIREWVAAARLKQPAMPRWPGPKKQHPSR

Dpp7

Dipeptidyl peptidase 2

500 amino acids

Plays an important role in the degradation of some oligopeptides.

Belongs to the peptidase S28 family.

55.114 kDa

MGLHPCSPVDHGVPSWVLVLLLTLGLCSLQATADSVLDPDFRENYFEQYMDHFNFESFSNKTFGQRFLVSDKFWKMGEGPIFFYTGNEGDIWSLANNSGFIVELAAQQEALLVFAEHRYYGKSLPFGVQSTQRGYTQLLTVEQALADFAVLLQALRHNLGVQDAPTIAFGGSYGGMLSAYMRMKYPHLVAGALAASAPVIAVAGLGNPDQFFRDVTADFYGQSPKCAQAVRDAFQQIKDLFLQGAYDTISQNFGTCQSLSSPKDLTQLFGFARNAFTVLAMMDYPYPTNFLGPLPANPVKVGCERLLSEGQRIMGLRALAGLVYNSSGMEPCFDIYQMYQSCADPTGCGTGSNARAWDYQACTEINLTFDSNNVTDMFPEIPFSDELRQQYCLDTWGVWPRPDWLQTSFWGGDLKAASNIIFSNGDLDPWAGGGIQRNLSTSIIAVTIQGGAHHLDLRASNSEDPPSVVEVRKLEATLIREWVAAARLKQPAEAQWPGPK

DPP7

Dipeptidyl peptidase 2

492 amino acids

Plays an important role in the degradation of some oligopeptides.

Belongs to the peptidase S28 family.

54.341 kDa

MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL