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DPEP1

Gene
DPEP1
Protein
Dipeptidase 1
Organism
Homo sapiens
Length
411 amino acids
Function
Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
Mass
45.674 kDa
Sequence
MWSGWWLWPLVAVCTADFFRDEAERIMRDSPVIDGHNDLPWQLLDMFNNRLQDERANLTTLAGTHTNIPKLRAGFVGGQFWSVYTPCDTQNKDAVRRTLEQMDVVHRMCRMYPETFLYVTSSAGIRQAFREGKVASLIGVEGGHSIDSSLGVLRALYQLGMRYLTLTHSCNTPWADNWLVDTGDSEPQSQGLSPFGQRVVKELNRLGVLIDLAHVSVATMKATLQLSRAPVIFSHSSAYSVCASRRNVPDDVLRLVKQTDSLVMVNFYNNYISCTNKANLSQVADHLDHIKEVAGARAVGFGGDFDGVPRVPEGLEDVSKYPDLIAELLRRNWTEAEVKGALADNLLRVFEAVEQASNLTQAPEEEPIPLDQLGGSCRTHYGYSSGASSLHRHWGLLLASLAPLVLCLSLL
Protein
Dipeptidase 1: DPEP1

Gene
DPEP1
Protein
Dipeptidase 1
Organism
Bos taurus
Length
410 amino acids
Function
Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity (By similarity).
Similarity
Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
Mass
45.127 kDa
Sequence
MWTGWWLWPLVAVCTADQFRDNAVRLMQSTPVIDGHNDLPWQLLKRFNNQLQDPRANLTSLNGTHTNIPKLKAGFVGAQFWSAYTPCDTQNKDSVKRTLEQIDVIQRMCQLYPETFLCVTDSAGIQQAFQEGKVASLVGVEGGHSIDSSLGVLRALYHLGMRYLTLTHSCNTPWADNWLVDTGEDEAQSQGLSSFGQSVVKEMNRLGVIIDLAHVSVATMEAALQLSKAPVIFSHSSAYSVCRHRRNVPDHVLQLVKQTGSLVMVNFYNDYVSCKAEANLSQVADHLDYIKKVAGAGAVGFGGDYDGVSRLPSGLEDVSKYPDLVAELLRRQWTEEEVRGALAENLLRVFKAVEQASDHKQAPGEEPIPLGQLEASCRTNYGYSGAPSLHLQPGTLLASLVTLLLSLCLL
Protein
Dipeptidase 1: DPEP1

Gene
Dpep1
Protein
Dipeptidase 1
Organism
Mus musculus
Length
410 amino acids
Function
Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
Mass
45.722 kDa
Sequence
MVIIWWFWSLLAICASDSFRDQAVAIMRTTPVIDGHNDLPWQLLNLFNNQLLRPDADLNKLAQTHTNIPKLKAGFVGGQFWSAYMPCDTQNKDAVKRILEQMDVIHRMCQLYPETFMCVTNSSDILQAFRRGKVASLIGVEGGHLIDSSLGVLRTLYHLGMRYLTLTHNCNTPWADNWLVDRGDDEAESHGLSPFGKRLLNEMNRLGVMIDLSHVSVATMKDALQISRAPVIFSHSSAYSLCPHRRNVPDDVLQLVKNTSSLVMVNFFSNFVSCSDSATLPQVADHLDHIKKVAGAGAVGLGGDYDGVTMLPVGLEDVSKYPDLIAELLRRNWTETEVRGLLADNLIRVFSEVELVSNNMQSPEEVPITLKELDGSCRTYYGYSQAHSIHLQTGALVASLASLLFRLHLL
Protein
Dipeptidase 1: Dpep1

Gene
DPEP1
Protein
Dipeptidase 1
Organism
Oryctolagus cuniculus
Length
410 amino acids
Function
Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
Mass
45.305 kDa
Sequence
MWTSWWLWPLVAVCTADSFLDQAVQILRVTPVIDGHNDLPWQLLNKFNNRLQDSRANLTVLADTHTNIPKLRAGFVGGQFWSAYTPCDTQNKDTVRRTLEQMDVVHRMCQLYPETFLCVTDSAGIQQAFREGKVASLIGVEGGHSIDSSLGVLRALYRLGMRYLTLTHNCNTPWADNWLVDRGDDEAQSGGLSVFGQRVVREMNRLGVMIDLAHVSVATMKAALQLSTAPVIFSHSSAFTVCAHKRNVPDDVLQLVKETGSLVMVNFYNDYVSCASEATLSQVADHLDYIKNVAGAAAVRFGGDFDGVTRLPVGLEDVSKYPDLVAELLRRGWTEAEVRGALAENLLRVFREVEQVSNQAQVPEEEPISLEQLGGSCRTQYGYSEAPSLHRRPGALLASLSLLLLSLGLL
Protein
Dipeptidase 1: DPEP1

Gene
Dpep1
Protein
Dipeptidase 1
Organism
Rattus norvegicus
Length
410 amino acids
Function
Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
Mass
45.522 kDa
Sequence
MLIIWWFWSLLAICASDSFRNQAENIMRTTPVIDGHNDLPWQMLTLFNNQLRKSEANLSALAETHTNIPKLRAGFVGGQFWSAYMPCDTQNKDAVKRILEQIDVIHRMCQLYPETFECVTNSSDILQAFRRGKVASLIGVEGGHLIDSSLGVLRTLYHLGMRYLTLTHNCNTPWADNWLVDKGDDEAESQGLSPFGKLVLNEMNRLGVMIDLSHVSVATMKDALQLSKAPVIFSHSSAYSVCPHRRNVPDDVLQLVKSTNSLVMVNFYNQFVSCSDSATLSQVADHLDHIKKVAGAGAVGLGGDYDGVTNLPVGLEDVSKYPDLIAELLRRNWTETEVRGLLAENLLRVFSAVELVSNIMQVPEEETIPVEKLDGSCRTFYGHSRAPSIHLQIGALLASLASLVFSLHLL
Protein
Dipeptidase 1: Dpep1

Gene
DPEP1
Protein
Dipeptidase 1
Organism
Ovis aries
Length
410 amino acids
Function
Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity. In lung tissue, it may terminate or significantly reduce the leukotriene induced signal for bronchospasm.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
Mass
45.096 kDa
Sequence
MWTGWWLWPLVAVCTADQFRDNAVRLMQSTPVIDGHNDLPWALLKKFNNQLQDPRANLTSLNSTHTNIPKLKAGFVGAQFWSAYTPCDTQNKDSVKRTVEQIDVIQRMCQLYPETFLCVTDSAGIQQAFQEGKVASLVGVEGGHSIDSSLGVLRALYHLGMRYLTLTHSCNTPWADNWLVDTGEDKAQSQGLSSFGQSVVKEMNRLGIIIDLAHVSVATMEAALQLSKAPVIFSHSSAYSLCHHRRNVPDHVLQLVKQTGSLVMVNFYNDYVSCKAEANLSQVADHLDYIKKVAGAGAVGFGGDYDGVSRLPSGLEDVSKYPDLVAELLRRQWTEEEVRGALAENLLRVFKAVEQASDHKQAPGEEPIPLGQLEASCRTKYGYSGTPSLHLQPGSLLASLVTLLLSLCLL
Protein
Dipeptidase 1: DPEP1

Gene
DPEP1
Protein
Dipeptidase 1
Organism
Sus scrofa
Length
409 amino acids
Function
Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
Mass
44.7 kDa
Sequence
MWTSWWLWPLVAVCAADQFRDLAVRIMQDTPVIDGHNDLPWQLLNLFNNQLQDPGANLSSLAHTHTNIPKLKAGFVGGQFWSAYVPCDTQNRDAVKRTLEQIDVIQRMCQAYPETFACVTSSTGIRQAFREGKVASLVGVEGGHSIDSSLGVLRALYHLGMRYMTLTHSCNTPWADNWLVDTGDDKAQSQGLSHFGQSVVKEMNRLGVMIDLAHVSVATMRAALKLSQAPVIFSHSSAYSLCPHRRNVPDDVLQLVKETGSLVMVNFYNDYVSCSAKANLSQVADHLDHIKKVAGAAAVGFGGDYDGVSRVPSGLEDVSKYPDLVAELLRRQWTEAEVRGALADNLLRVFEAVEQASNHAQVPGEEPIPLGQLEASCRTNYGYSAAPSLHLPPGSLLASLVPLLLLSLP
Protein
Dipeptidase 1: DPEP1