DIM1

Gene

DIM1

Protein

Dimethyladenosine transferase

Organism

Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)

Length

384 amino acids

Function

Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

Mass

42.546 kDa

Sequence

MPKTAKNKRNNAASGPYDKKSKGSGSTNIFKFDKDYGQHILKNPGISDAIVEKAFLKPTDVVVEVGPGTGNITVRALERAKKVIAIELDPRMGAEVTKRVQGTPLAKKLEVILGDVIKLPQIPPCDALISNTPYQISSPLIFKMLSMPQPPRVAVLMFQREFAKRLVAKPGDSLYSRLTVNVNFWATCTHIMKVGKANFKPPPKVESDVVRIEPYLGSARPNIAFEEFDGLLRIAFNRKNKTLRAAFSIKEVLALCEKNYKVYCTLHNIPLDESVLSDPSLTADMDVDMDANSDTDNDNDGDAMEEDDDDMPTFFKEVKEAEAAKEAAKTPSKNPKSKVALIVRAKINKVLTKTGLANKRARQCDQNDFLKLLLAFHEEGIHFS

Protein

Dimethyladenosine transferase: DIM1

Gene

DIM1

Protein

Dimethyladenosine transferase

Organism

Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)

Length

384 amino acids

Function

Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

Mass

42.546 kDa

Sequence

Protein

Dimethyladenosine transferase: DIM1

Gene

DIM1

Protein

Dimethyladenosine transferase

Organism

Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)

Length

327 amino acids

Function

Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

Mass

36.534 kDa

Sequence

MAKAARKKFSTSSDPTGSTVSAEKHLNSVFKFNTNLGQHILKNPLVAQGIVDKAGIKPSDIVLEVGPGTGNLTVRILEQARKVIASEMDPRMAAELTKRVHGTPNQKKLDILLGDFIKTELPYFDVCISNTPYQISSPLVFKLLNQPRPPRVSILMFQREFAMRLLARPGDSLYCRLSANVQMWANVTHIMKVSKNNFRPPPQVESSVVRIEVKVPRPNIDFNEWDGLLRICFVRKNKTIAAGFKSNNILDILEKNYKTFLSTANAAANGDDSMMVDDKSSMTDIVKAKIEQVLTETGFSDKRAAKLDQTDFLKLLYAFHQVGLHFA

Protein

Dimethyladenosine transferase: DIM1

Gene

DIM1

Protein

Dimethyladenosine transferase

Organism

Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)

Length

327 amino acids

Function

Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

Mass

36.534 kDa

Sequence

Protein

Dimethyladenosine transferase: DIM1

Gene

DIM1

Protein

Dimethyladenosine transferase

Organism

Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)

Length

320 amino acids

Function

Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

Mass

35.763 kDa

Sequence

MGKAVKKKYSGASSGGKEVDAEKHLTTVFKFNTDLGQHILKNPLVAQGIVDKAQIKPSDIVLEIGPGTGNLTVRILEQARKVVAVEFDPRMAAELTKRVHGTPVEKKLEILLGDFMKTELPYFDVCISNTPYQISSPLVFKLINQPKPPRVSILMFQREFAMRLLARPGDSLYCRLSANVQMWANVTHIMKVGKNNFRPPPKVESSVVRIEIKNPRPQVDFNEWDGLLRIVFVRKNRTIAAGFKSTTVLEILEKNYKAFLATQSAVPTTSSGDSLINEVKEKIEQVLSETGLAEKRAGKCDQTDFLKLLYGFHQVGIHFA

Protein

Dimethyladenosine transferase: DIM1

Gene

DIM1

Protein

Dimethyladenosine transferase

Organism

Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)

Length

320 amino acids

Function

Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

Mass

35.763 kDa

Sequence

Protein

Dimethyladenosine transferase: DIM1

Gene

DIM1

Protein

Dimethyladenosine transferase

Organism

Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)

Length

319 amino acids

Function

Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

Mass

35.818 kDa

Sequence

MGKAAKKKYSGISTGKEVPSEQHMNTVFKFNTDLGQHILKNPLVAQGIVDKAQIKPSDIVLEVGPGTGNLTVRILEQARKVVAVEFDPRMAAELTKRVHGTPAEKKLEIMLGDFMKTELPYFDICISNTPYQISSPLVFKLINQPRPPRVSILMFQREFAMRLLARPGDSLYCRLSANVQMWANVTHVMKVGRNNFRPPPQVESSVVRIEIKTPRPPVDFNEWDGLLRIVFVRKNRTISAGFKSTAVLEIMEKNYKAYLATTNDAMVDDAKGSLAEQVKQKIETVLAETGLSDKRAGKCDQTDFLKLLYAFHQVGLHFS

Protein

Dimethyladenosine transferase: DIM1

Gene

DIM1

Protein

Dimethyladenosine transferase

Organism

Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)

Length

319 amino acids

Function

Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

Mass

35.818 kDa

Sequence

Protein

Dimethyladenosine transferase: DIM1

Gene

DIM1

Protein

Dimethyladenosine transferase

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

318 amino acids

Function

Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

Mass

35.951 kDa

Sequence

MGKAAKKKYSGATSSKQVSAEKHLSSVFKFNTDLGQHILKNPLVAQGIVDKAQIRPSDVVLEVGPGTGNLTVRILEQAKNVVAVEMDPRMAAELTKRVRGTPVEKKLEIMLGDFMKTELPYFDICISNTPYQISSPLVFKLINQPRPPRVSILMFQREFALRLLARPGDSLYCRLSANVQMWANVTHIMKVGKNNFRPPPQVESSVVRLEIKNPRPQVDYNEWDGLLRIVFVRKNRTISAGFKSTTVMDILEKNYKTFLAMNNEMVDDTKGSMHDVVKEKIDTVLKETDLGDKRAGKCDQNDFLRLLYAFHQVGIHFS

Protein

Dimethyladenosine transferase: DIM1

Gene

DIM1

Protein

Dimethyladenosine transferase

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

318 amino acids

Function

Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

Mass

35.951 kDa

Sequence

Protein

Dimethyladenosine transferase: DIM1

Gene

DIM1

Protein

Dimethyladenosine transferase

Organism

Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)

Length

317 amino acids

Function

Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

Mass

35.92 kDa

Sequence

MAKADKKKYSGATTNKQVAAEKHLTSVFKFNTDLGQHILKNPLVAQGIVDKAQIKPSDIVLEVGPGTGNLTVRILEQARKVVAVEMDPRMAAELTKRVHGTPAEKKLEIMLGDFMKTELPYFDICISNTPYQISSPLVFKLINQPRPPRVSILMFQREFAMRLLARPGDSLYCRLSANVQMWANVTHIMKVGRNNFRPPPQVESSVVRIEIKNPRPQIDFNEWDGLLRIVFVRKNRTISAGFKSTTVLEILEKNYKTFLAINNQSIDETENLQSLIKQKIETVLKETGLAEKRAGKCDQTDFLKLLYAFHQVGIHFS

Protein

Dimethyladenosine transferase: DIM1

Gene

DIM1

Protein

Dimethyladenosine transferase

Organism

Yarrowia lipolytica (strain CLIB 122 / E 150)

Length

317 amino acids

Function

Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

Mass

35.351 kDa

Sequence

MAKAPAKKFSGGAQRESAGGEQRKTAVFKMNTDLGQHILKNPLVAQGIVDKSDIKPSDTVLEVGPGTGNLTVRILEKARKVIAVEMDPRMAAELTKRVQGKPEQKKLEIMLGDCIKTELPYFDVCISNTPYQISSPLVFKLLNQPRPPRVSVLMFQHEFAMRLLARPGDSLYCRLSVNVQMWAKVSHVMKVGRGNFRPPPNVESSVVKIEVKNPRPPIDFNEWDGLLRVCFVRKNKTINAGFKTSAVLAVLEKNYQTWLSTQGEIIPEGSNLSDVVKQKINKILTDTGIGEMRSAKCDQTEFLTLLNEFHKAGIYFA

Protein

Dimethyladenosine transferase: DIM1

Gene

DIM1

Protein

Dimethyladenosine transferase

Organism

Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)

Length

317 amino acids

Function

Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

Mass

35.92 kDa

Sequence

Protein

Dimethyladenosine transferase: DIM1

Gene

DIM1

Protein

Dimethyladenosine transferase

Organism

Yarrowia lipolytica (strain CLIB 122 / E 150)

Length

317 amino acids

Function

Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

Mass

35.351 kDa

Sequence

Protein

Dimethyladenosine transferase: DIM1

Gene

dim1

Protein

Dimethyladenosine transferase

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

Length

307 amino acids

Function

Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

Mass

34.678 kDa

Sequence

MGKIRVRNNNAASDAEVRNTVFKFNKDFGQHILKNPLVAQGIVDKADLKQSDTVLEVGPGTGNLTVRMLEKARKVIAVEMDPRMAAEITKRVQGTPKEKKLQVVLGDVIKTDLPYFDVCVSNTPYQISSPLVFKLLQQRPAPRAAILMFQREFALRLVARPGDPLYCRLSANVQMWAHVKHIMKVGKNNFRPPPLVESSVVRIEPKNPPPPLAFEEWDGLLRIVFLRKNKTIGACFKTSSIIEMVENNYRTWCSQNERMVEEDFDVKSLIDGVLQQCNLQDARASKCGQTEFLSLLHAFHQVGVHFA

Protein

Dimethyladenosine transferase: dim1

Gene

dim1

Protein

Dimethyladenosine transferase

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

Length

307 amino acids

Function

Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

Mass

34.678 kDa

Sequence

Protein

Dimethyladenosine transferase: dim1

Gene

dim1

Protein

Mitosis protein dim1

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

Length

142 amino acids

Function

Plays a fundamental role as a protein essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis. May play a role in mitotic spindle formation and/or function. May have a role in the maintenance or establishment of the steady-state level of the APC complex.

Similarity

Belongs to the DIM1 family.

Mass

16.971 kDa

Sequence

MSYFLPHLHSGWHVDQAILSEQERLVVIRFGRDHDEECIKQDEVLYRIAEKVVNMAVIYLVDIDEVPDFNKMYELYDRTTIMFFYRNKHMMIDLGTGNNNKINWPLEDKQEMIDIIETIFRGARKGKGLVISPKDYSTRHRY

Protein

Mitosis protein dim1: dim1