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DET2

Gene
DET2
Protein
Steroid 5-alpha-reductase DET2
Organism
Arabidopsis thaliana
Length
262 amino acids
Function
Involved in a reduction step in the biosynthesis of the plant steroid, brassinolide; acts at the second step in brassinolide biosynthesis in the 5alpha-reduction of (24R)- 24-methylcholest-4-en-3-one, which is further modified to form campestanol. Can use progesterone, testosterone, androstenedione and campestenone as substrate.
Similarity
Belongs to the steroid 5-alpha reductase family.
Mass
30.635 kDa
Sequence
MEEIADKTFFRYCLLTLIFAGPPTAVLLKFLQAPYGKHNRTGWGPTVSPPIAWFVMESPTLWLTLLLFPFGRHALNPKSLLLFSPYLIHYFHRTIIYPLRLFRSSFPAGKNGFPITIAALAFTFNLLNGYIQARWVSHYKDDYEDGNWFWWRFVIGMVVFITGMYINITSDRTLVRLKKENRGGYVIPRGGWFELVSCPNYFGEAIEWLGWAVMTWSWAGIGFFLYTCSNLFPRARASHKWYIAKFKEEYPKTRKAVIPFVY

Gene
DET2
Protein
Steroid 5-alpha-reductase DET2
Organism
Gossypium hirsutum
Length
258 amino acids
Function
Involved in a reduction step in the biosynthesis of the plant steroid, brassinolide. Promotes cotton fibers (seed trichomes) initiation and elongation.
Similarity
Belongs to the steroid 5-alpha reductase family.
Mass
30.421 kDa
Sequence
MASDQTLFHYCLLTLYIIALPTWISLYFLQAPYGKHNRPGWGPTISPPLAWFLMESPTLWLTFFLFPSGQHFYNPKSFLLISPFLFHYFNRTVLYPLRLARNTTQTRGFPVSVAFMAFGFNLLNGYLQARWVSHYKDDYENEELFWWRFLAGLLIFVVGMWVNVRADKVLVGLKKQGDGGYKIPRGGLFELVSCPNYFGEIMEWFGWAVMTWSWVGFGFFLYTCANLMPRARATRLWYLEKFKDDYPKDRKAVIPFIY

Gene
DET2
Protein
Steroid 5-alpha-reductase DET2
Organism
Solanum lycopersicum
Length
257 amino acids
Function
Involved in a reduction step in the biosynthesis of the plant steroid, brassinolide. Can use progesterone, testosterone, androstenedione and campestenone as substrate.
Similarity
Belongs to the steroid 5-alpha reductase family.
Mass
29.802 kDa
Sequence
MFSSDENLFNFIVFFILVMAFPTFILCQFFTSPYGKHYTSADSGTTISPPIAWAFMESPTLWLTIIVFRLGKNYTNPLAFLLISPYLFHYTNRTIIYPLRLRSRNTKNNFPLNIAVTAFIFNLLNAYIQSRWVSHYANYQEDDWFWVRFGIGLVIFGSGMLLNIWADGVLLGLKSQGGGYKIPRGGLFDYVSSPNYLGEIMEWLGWALMTWSWAGLAFFVYTCANLVPRAVSNHKWYLQKFGEDYPKNRKAVFPFLY