About Products Protein Database Contact

DESI1

Gene
desi1
Protein
Desumoylating isopeptidase 1
Organism
Xenopus laevis
Length
169 amino acids
Function
Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins (By similarity). Has isopeptidase but not SUMO-processing activity (By similarity). Collaborates with ubqln4 in the export of ubiquitinated proteins from the nucleus to the cytoplasm (By similarity).
Similarity
Belongs to the DeSI family.
Mass
18.737 kDa
Sequence
METAEGPHLVRLYVYDMSRGLARRLSPVMLGKQLEGIWHTSIIVFDEEFFYGREGITSCLPGRTMLGEPDSVMELGITEVTEEIFLEYLSSLGESGFSGESYHLFDHNCNTFSNEVAQFLTGKKIPSYITELPSEVLSTPLGQALRPLLDSVQIQPAGGNIFNRQSGPS

Gene
DESI1
Protein
Desumoylating isopeptidase 1
Organism
Homo sapiens
Length
168 amino acids
Function
Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins. Has isopeptidase but not SUMO-processing activity (By similarity). Desumoylates ZBTB46 (By similarity). Collaborates with UBQLN4 in the export of ubiquitinated proteins from the nucleus to the cytoplasm (PubMed:29666234).
Similarity
Belongs to the DeSI family.
Mass
18.263 kDa
Sequence
MEPPNLYPVKLYVYDLSKGLARRLSPIMLGKQLEGIWHTSIVVHKDEFFFGSGGISSCPPGGTLLGPPDSVVDVGSTEVTEEIFLEYLSSLGESLFRGEAYNLFEHNCNTFSNEVAQFLTGRKIPSYITDLPSEVLSTPFGQALRPLLDSIQIQPPGGSSVGRPNGQS

Gene
Desi1
Protein
Desumoylating isopeptidase 1
Organism
Mus musculus
Length
168 amino acids
Function
Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins (PubMed:22370726, PubMed:22498933). Has isopeptidase but not SUMO-processing activity (PubMed:22370726, PubMed:22498933). Desumoylates ZBTB46 (PubMed:22370726). Collaborates with UBQLN4 in the export of ubiquitinated proteins from the nucleus to the cytoplasm (By similarity).
Similarity
Belongs to the DeSI family.
Mass
18.385 kDa
Sequence
MEPPNLYPVKLYVYDLSKGLARRLSPIMLGKQLEGIWHTSIVVHKDEFFFGSSGISSCTPGGTLLGPPDSVVDVGNTEVTEEIFLEYLSSLGESLFRGEAYNLFEHNCNTFSNEVAQFLTGRKIPSYITDLPSEVLSTPFGQALRPFLDSIQIQPPGGNSVGRPNGQS

Gene
Desi1
Protein
Desumoylating isopeptidase 1
Organism
Rattus norvegicus
Length
168 amino acids
Function
Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins. Has isopeptidase but not SUMO-processing activity. Desumoylates ZBTB46 (By similarity). Collaborates with UBQLN4 in the export of ubiquitinated proteins from the nucleus to the cytoplasm (By similarity).
Similarity
Belongs to the DeSI family.
Mass
18.385 kDa
Sequence
MEPPNLYPVKLYVYDLSKGLARRLSPIMLGKQLEGIWHTSIVVHKDEFFFGSSGISSCTPGGTLLGPPDSVVDVGNTEVTEEIFLEYLSSLGESLFRGEAYNLFEHNCNTFSNEVAQFLTGRKIPSYITDLPSEVLSTPFGQALRPFLDSIQIQPPGGNSVGRPNGQS