DENND1C

Gene

DENND1C

Protein

DENN domain-containing protein 1C

Organism

Homo sapiens

Length

801 amino acids

Function

Guanine nucleotide exchange factor (GEF) which may activate RAB8A, RAB13 and RAB35. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.

Mass

87.065 kDa

Sequence

MESRAEGGSPAVFDWFFEAACPASLQEDPPILRQFPPDFRDQEAMQMVPKFCFPFDVEREPPSPAVQHFTFALTDLAGNRRFGFCRLRAGTQSCLCILSHLPWFEVFYKLLNTVGDLLAQDQVTEAEELLQNLFQQSLSGPQASVGLELGSGVTVSSGQGIPPPTRGNSKPLSCFVAPDSGRLPSIPENRNLTELVVAVTDENIVGLFAALLAERRVLLTASKLSTLTSCVHASCALLYPMRWEHVLIPTLPPHLLDYCCAPMPYLIGVHASLAERVREKALEDVVVLNVDANTLETTFNDVQALPPDVVSLLRLRLRKVALAPGEGVSRLFLKAQALLFGGYRDALVCSPGQPVTFSEEVFLAQKPGAPLQAFHRRAVHLQLFKQFIEARLEKLNKGEGFSDQFEQEITGCGASSGALRSYQLWADNLKKGGGALLHSVKAKTQPAVKNMYRSAKSGLKGVQSLLMYKDGDSVLQRGGSLRAPALPSRSDRLQQRLPITQHFGKNRPLRPSRRRQLEEGTSEPPGAGTPPLSPEDEGCPWAEEALDSSFLGSGEELDLLSEILDSLSMGAKSAGSLRPSQSLDCCHRGDLDSCFSLPNIPRWQPDDKKLPEPEPQPLSLPSLQNASSLDATSSSKDSRSQLIPSESDQEVTSPSQSSTASADPSIWGDPKPSPLTEPLILHLTPSHKAAEDSTAQENPTPWLSTAPTEPSPPESPQILAPTKPNFDIAWTSQPLDPSSDPSSLEDPRARPPKALLAERAHLQPREEPGALNSPATPTSNCQKSQPSSRPRVADLKKCFEG

Protein

DENN domain-containing protein 1C: DENND1C

Gene

Dennd1c

Protein

DENN domain-containing protein 1C

Organism

Mus musculus

Length

786 amino acids

Function

Guanine nucleotide exchange factor (GEF) which may activate RAB8A, RAB13 and RAB35. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.

Mass

86.689 kDa

Sequence

MGSTETRHPPAMFDWFFEAGCPNSLEEDPPILRQFPPDFQEQEAMQMVPRFCFPFDIEREPPSPAVQHFTFALTDLVGNRRFGFCRLRAGARSCLCILSHFPWFEVFYKILNNVGDLLAQNQVAEAEELLQNLQQHPLLGPRFSGRSEMDSSITVRSECGILPPALGNSKLLSCFVAPDAASLPSIPENRNLTELVVAVTDENIVGLFAALLAERRVLLTASKLSTLTACVHASCALLYPMRWEHVLIPTLPPHLLDYCCAPMPYLIGVHGSLAERVREKALEDVVVLNADSNTLETPFDDVQALPPDVVSLLRLRLRKVALSPGEGVSRLFLKVQALLFGGYRDALVCIPGQPVTFSEEAFLAQKPGAPLQAFHKKAVHLQLFKQFIESRLEKLNAGEGFSDQFEQEIIACRGASSGTLRSYQLWVDSLKKGSDALLHSMKTKTQPAVRNMYRSGDSLQEYCASKAKSGLKGMQNLLTIKDGDSGLQRGGSLRTPSLTSRSDRLQQRLPISQHFGQNRPLRPSRRLKTEEGPSEPLRERSPTLSPGDTQNPWAEDTLDGSFLGSGEELDLLSEILDSLNVETKSGDLQRASQSLDCCQRGAASESCSSLPDIPVGLPWQLEEDKRSQDPQPWSLPGDLSLLQDTPFSEVVSYSKNSCSQPFQQSPPSQGDPGPSLSKLDPRPSQSPCPKLLRVPTRHSPPESPQLLVSTEPNSDAVQRLQSISSPSCSHSAENPRNQPPQVLLGQACVQPLEELGAPTYVSHVSTQQRPQDKQPRVADLKKCFEN

Protein

DENN domain-containing protein 1C: Dennd1c