Protein
Mitochondrial glycine transporter
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Function
Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix.
Similarity
Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
Sequence
MVSDVSEPSDTTPEVVVQQQPQPKTLTHLISGASAGLISAISLQPFDLLKTRLQQQQRSNIKYRTTISKELKKLTHIRDLWRGALPSTLRTSVGAGLYFTILSSARNGISDYKRSSDSVSDTSILPKLSPFENLATGFIVRAVVGIITMPITIVKTRYESNIYNYNSMYEGFENIYLDGNQKGQGSLKNFFKGSFATLARDCPYAGMYVLFYELFKNDILTKVVPPIDETENGPITRSTIINTSAAILAASVSTTITAPFDAIKTRLQLSSIVASKKMTLWSATKDLMREDGGVKNLFRGLSLRFGRKGLSSGISWCIYEELIKSNFAQVIITKSDKKLV