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DDOST

Gene
DDOST
Protein
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
Organism
Homo sapiens
Length
456 amino acids
Function
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity). Required for the assembly of both SST3A- and SS3B-containing OST complexes (PubMed:22467853).
Similarity
Belongs to the DDOST 48 kDa subunit family.
Mass
50.801 kDa
Sequence
MGYFRCARAGSFGRRRKMEPSTAARAWALFWLLLPLLGAVCASGPRTLVLLDNLNVRETHSLFFRSLKDRGFELTFKTADDPSLSLIKYGEFLYDNLIIFSPSVEDFGGNINVETISAFIDGGGSVLVAASSDIGDPLRELGSECGIEFDEEKTAVIDHHNYDISDLGQHTLIVADTENLLKAPTIVGKSSLNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGKNTLLIAGLQARNNARVIFSGSLDFFSDSFFNSAVQKAAPGSQRYSQTGNYELAVALSRWVFKEEGVLRVGPVSHHRVGETAPPNAYTVTDLVEYSIVIQQLSNGKWVPFDGDDIQLEFVRIDPFVRTFLKKKGGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYERFIPSAYPYYASAFSMMLGLFIFSIVFLHMKEKEKSD

Gene
DDOST
Protein
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
Organism
Canis lupus familiaris
Length
445 amino acids
Function
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (PubMed:12887896). Required for the assembly of both SST3A- and SS3B-containing OST complexes (By similarity).
Similarity
Belongs to the DDOST 48 kDa subunit family.
Mass
49.634 kDa
Sequence
MRRRRKMEAGAAARAWSLLWLLLPLLGPVCASGPRTLVLLDNLNLRETHSLFFRSLKDRAFELTFKTADDPSLSLIKYGEFLYDNLIIFSPSVEDFGGNINVETISTFIDGGGSVLVAASSDIGDPLRELGSECGIEFDEEKTAVIDHHNYDVSDLGQHTLIVADPENLLKAPTIVGRSSLNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGKNTLLIAGLQARNNARVVFSGSLDFFSDAFFNSAVQKAAPGSQRYSQTGNYELAVALSRWVFKEEGVLRVGPVSHHRVGETAPPNAYTVTDLVEYSIVIEQLSNGRWVPFDGDDIQLEFVRIDPFVRTFLKKKGGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLHSSTQVSVRPLQHTQYERFIPSAYPYYASAFSMMLGLFIFSTVFLHMKEKEKSD

Gene
ddost
Protein
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
Organism
Danio rerio
Length
441 amino acids
Function
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity). Required for the assembly of both SST3A- and SS3B-containing OST complexes (By similarity).
Similarity
Belongs to the DDOST 48 kDa subunit family.
Mass
48.534 kDa
Sequence
MATALSGGFSKNALFILSAALMLQAVLGDGKTLVLLDNPNIRDTHSIFFRSLADRGFDLTFKTADDPGLSLIKYGQFLYDHLILFSPSVEDFGGNINVETITAFIDGGGNVLVAASSDIGDPLRELGSECGIEFDEEKTAVIDHHNYDISDPGEHTLIVADPENLLKAPTIVGKPTDKPVLFKGVGMVADPDNPLVLDILTGSSTSYSYFPDRPITQYPHAVGKNTLLIAGLQARNNARVVFSGSLHFFSDAFFNSAVQKAATGSKRYEQTGNQDLAEALSRWVFKEAGVLRVGDVTHHPVGESTPPAAYTVTDLVEYGIVIEMLSGGKWVPFDGDDIQLEFVRIDPFVRTYLKKNGGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYERFIPSAFPYYASAFSMMAGLFVFSVVFLHMREKEKSD

Gene
Ddost
Protein
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
Organism
Mus musculus
Length
441 amino acids
Function
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity). Required for the assembly of both SST3A- and SS3B-containing OST complexes (By similarity).
Similarity
Belongs to the DDOST 48 kDa subunit family.
Mass
49.028 kDa
Sequence
MKMDPRLAVRAWPLCGLLLAVLGCVCASGPRTLVLLDNLNVRDTHSLFFRSLKDRGFELTFKTADDPSLSLIKYGEFLYDNLIIFSPSVEDFGGNINVETISAFIDGGGSVLVAASSDIGDPLRELGSECGIEFDEEKTAVIDHHNYDVSDLGQHTLIVADTENLLKAPTIVGKSSLNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGRNTLLIAGLQARNNARVIFSGSLDFFSDAFFNSAVQKATPGAQRYSQTGNYELAVALSRWVFKEEGVLRVGPVSHHRVGEMAPPNAYTVTDLVEYSIIIEQLSNGKWVPFDGDDIQLEFVRIDPFVRTFLKRKGGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYERFIPSAYPYYASAFSMMAGLFIFSIVFLHMKEKEKSD

Gene
Ddost
Protein
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
Organism
Rattus norvegicus
Length
441 amino acids
Function
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity). Required for the assembly of both SST3A- and SS3B-containing OST complexes (By similarity).
Similarity
Belongs to the DDOST 48 kDa subunit family.
Mass
48.896 kDa
Sequence
MKMVPRLAVRAWPLCGLLLAALGCVCASGPRTLVLLDNLNVRDTHSLFFRSLKDRGFELTFKTADDPSLSLIKYGEFLYDNLIIFSPSVEDFGGNINVETISAFIDGGGSVLVAASSDIGDPLRELGSECGIEFDEEKTAVIDHHNYDVSDLGQHTLIVADTENLLKAPTIVGKSSLNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGRNTLLIAGLQARNNARVIFSGSLDFFSDAFFNSAVQKAAPGAQRYSQTGNYELAVALSRWVFKEEGVLRVGPVSHHRVGETAPPNAYTVTDLVEYSIVIEQLSNGKWVPFDGDDIQLEFVRIDPFVRTFLKRKGGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYERFIPSAYPYYASAFSMMAGLFLFSVVFLHMKEKEKSD

Gene
DDOST
Protein
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
Organism
Bos taurus
Length
439 amino acids
Function
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity). Required for the assembly of both SST3A- and SS3B-containing OST complexes (By similarity).
Similarity
Belongs to the DDOST 48 kDa subunit family.
Mass
48.791 kDa
Sequence
MATRAARVWSGWWLLLLPLLGLAGASGPRTLVLLDNLNLRETHSLFFRSLKDRGFVLTFKTADDPSLSLIKYGEFLYDNLIIFSPSVEDFGGNINVETISAFIDGGGSVLVAASSDIGDPLRELGSECGIEFDEEKTAVIDHHNYDVSDLGQHTLIVADTENLLKAPTIVGKSSLNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGKNTLLIAGLQARNNARVIFSGSLDFFSDAFFNSAVQKAAPGSQRYSQTGNYELAVALSRWVFKEEGVLRVGPVSHHRVGETAPPNAYTVTDLVEYSIVIEQLSDGKWVPFDGDDIQLEFVRIDPFVRTFLKRKGGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYERFIPSAYPYYASAFSMMLGLFIFSVVFLHMKEKEKSD

Gene
DDOST
Protein
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
Organism
Sus scrofa
Length
439 amino acids
Function
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (PubMed:11443278). N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity). Required for the assembly of both SST3A- and SS3B-containing OST complexes (By similarity).
Similarity
Belongs to the DDOST 48 kDa subunit family.
Mass
48.863 kDa
Sequence
MELGAAARAWSLLWLLLPLLGLVGASGPRTLVLLDNLNLRETHSLFFRSLKDRGFVLTFKTADDPSLSLIKYGEFLYDNLIVFSPSVEDFGGNINVETISTFIDGGGSVLVAASSDIGDPLRELGSECGIEFDEEKTAVIDHHNYDVSDLAQHTLIVADTENLLKAPTIVGKSSLNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGKNTLLIAGLQARNNARVIFSGSLDFFSDAFFNSAVQKATPGSQRYPQTGNYELAVALSRWVFKEEGVLRVGPVSHHRVGEKAPPNAYTVTDLVEYSIVIEQLSEGRWVPFDGDDIQLEFVRIDPFVRTFLKRKGGKYSVQFKFPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYERFIPSAYPYYASAFSMMVGLFIFSVVFLHMKEKEKSD

Gene
DDOST
Protein
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
Organism
Pongo abelii
Length
439 amino acids
Function
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity). Required for the assembly of both SST3A- and SS3B-containing OST complexes (By similarity).
Similarity
Belongs to the DDOST 48 kDa subunit family.
Mass
48.783 kDa
Sequence
MEPSTAARAWALFWLLPPLLGAVCASGPRTLVLLDNLNVRETHSLFFRSLKDRGFELTFKTADDPSLSLIKYGEFLYDNLIIFSPSVEDFGGNINVETISAFIDGGGSVLVAASSDIGDPLRELGSECGIEFDEEKTAVIDHHNYDISDLGQHTLIVADTENLLKAPTIVGKSSLNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGKNTLLIAGLQARNNARVIFSGSLDFFSDSFFNSAVQKAAPGSQRYSQTGNYELAVALSRWVFKEEGVLRVGPVSHHRVGETAPPNAYTVTDLVEYSIVIQQLSNGKWVPFDGDDIQLEFVRIDPFVRTFLKKKGGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYERFIPSAYPYYASAFSMMLGLFIFSIVFLHMKEKEKSD

Gene
ddost
Protein
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
Organism
Xenopus laevis
Length
438 amino acids
Function
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity). Required for the assembly of both SST3A- and SS3B-containing OST complexes (By similarity).
Similarity
Belongs to the DDOST 48 kDa subunit family.
Mass
48.712 kDa
Sequence
MASLRLSVLLVSVSWLLLLVSGLRAGPRTLVLMENINLRETHSLFFRSLSDRGFDLSFKTADDPSLSLIKYGEFLYDNLIIFSPSVEDFGGNINIETISSFIDGGGSVLVAASSDIGDPLRELGSECGIEFDEEKTAVIDHHNYDISDPGQHTLIVADSENLLKAPTIVGKTPLNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGKNTLLIAGLQARNNARVVFSGSLDFFSDSFFNSAVQKAASGSNRYAKTGNYELAMALSRWVFKEEGVLRVGEVSHHRVGESSPPSAYTVTDLVEYSIVIEKLSDGKWVPFDGDDIQLEFVRIDPFVRTFLKKNGGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSTTQISVRPLQHTQYERFIPSAYPYYASAFSVMFGLFIFSIVFLHMKEKEKSD

Gene
ddost
Protein
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
Organism
Xenopus tropicalis
Length
437 amino acids
Function
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity). Required for the assembly of both SST3A- and SS3B-containing OST complexes (By similarity).
Similarity
Belongs to the DDOST 48 kDa subunit family.
Mass
48.265 kDa
Sequence
MASLRVSVLLVAASCLLLGSGLRAGPRTLVLLENINLRETHSLFFRSLSDRGFDLSFRTADDPSLSLIKYGEFLYDNLIIFSPSVEDFGGNINIETISSFIDGGGSVLVAASSDIGDPLRELGSECGIEFDEDKTAVIDHHNYDISDPGQHSLIVADSESLLKAPTIVGKAPLNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGKNTLLIAGLQARNNARVVFSGSMDFFSDAFFNSAVQKAAGGSNRYAKTGNYELAVALSRWVFKEEGVLRVGQVSHHRVGESSPPSAYTVTDLVEYSIVIEQLSNGKWVPFDGDDIQLEFVRIDPFVRTFLKKNGGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSTTQVSVRPLQHTQYERFIPSAYPYYASAFSVMFGLFIFSIVFLHMKEKEKSD

Gene
ddost
Protein
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
Organism
Dictyostelium discoideum
Length
426 amino acids
Function
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Similarity
Belongs to the DDOST 48 kDa subunit family.
Mass
47.889 kDa
Sequence
MMMKSILITFIIASALLSSVFADIGGKRTLVVLDDLSIKKTHSTFFKNLENKGYKLQFEQSNTKVVLEKYGDFNFDNLILFSPTSESLSFSSADVTRFIDGGNNVLFAGSNVISENIRDIAAECGMEIEEDKTLIFDHFNYDKSQSDHSVLVADQFIDDSPIILQGLNKPILFKGIGHKIRNNPLNYAILTGSSTAFSAKAISGVSTKLMGKSCGLVSSLQARNNARVTFSGSLDLFSDKSFYSKIDNKESGNKEFVERLVSWTFQERGILRASELELVKISTESNSTVAPDVFTIKDEVKYSLKVEEFDGIKGKWVPYVGSLQLEVIMLDPYIRTFIKGDANGLYKIHFKLPDVYGVFTFEASIHKSGYSTLDHIYRKPILPFRHDSYERFIPAAFPYYATCFSMLIGTFIFSIIFLFNKDQLNK

Gene
DDOST
Protein
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
Organism
Gallus gallus
Length
413 amino acids
Function
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity). Required for the assembly of both SST3A- and SS3B-containing OST complexes (By similarity).
Similarity
Belongs to the DDOST 48 kDa subunit family.
Mass
45.912 kDa
Sequence
GPRSLVLLENLNLRDTHSLFFRSLADRGFELTFRTADDAGLSLIKYGEFLYDNLIIFSPSIEDFGGNINVETITAFIDGGGSVLVAASSDIGDPLRELGSECGIEFDEERTAVIDHHNYDISDPGQHTLIVADAENLLKAPTIVGKKALNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGKNTLLIAGLQARNNARVVFSGSLDFFSDAFFSSAVQKAAPGSKRYSQTGNYELAVALSRWVFKEEGVLRVGAVSHHRVGELAPPNAYTVTDLVEYSIVIEKLSDGKWIPFDGDDIQLEFVRIDPFVRTFLKRNGGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYERFIPSAYPYYAGAFSMMVGLFMFSIVFLHMKEKEKSD