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DCUN1D2

Gene
DCUN1D2
Protein
DCN1-like protein 2
Organism
Homo sapiens
Length
259 amino acids
Function
Potently stimulates the neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8-conjugating E2 enzyme UBC12. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.
Mass
30.179 kDa
Sequence
MHKLKSSQKDKVRQFMACTQAGERTAIYCLTQNEWRLDEATDSFFQNPDSLHRESMRNAVDKKKLERLYGRYKDPQDENKIGVDGIQQFCDDLSLDPASISVLVIAWKFRAATQCEFSRKEFLDGMTELGCDSMEKLKALLPRLEQELKDTAKFKDFYQFTFTFAKNPGQKGLDLEMAVAYWKLVLSGRFKFLDLWNTFLMEHHKRSIPRDTWNLLLDFGNMIADDMSNYDEEGAWPVLIDDFVEYARPVVTGGKRSLF

Gene
Dcun1d2
Protein
DCN1-like protein 2
Organism
Mus musculus
Length
259 amino acids
Function
Potently stimulates the neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8-conjugating E2 enzyme UBC12. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity (By similarity).
Mass
30.068 kDa
Sequence
MHKLKSAQKDKVRQFMACTQASERTAIYCLTQNEWKLDEATDSFFQNPEAFHRESMKSSVDQKKLEQLYSRYKDPQDENKIGIDGIQQFCDDLSLDPASISVLVIAWKFRAATQCEFSKKEFVDGMTELGCDSTERLKALLPRLEQELKDPAKFKDLYQFTFTFAKNPGQKGLDLEMAVAYWKLVLSGRFKFLDLWNTFLLEHHKRSIPRDTWNLLLDFGNMIADDLSNYDEEGAWPVLIDDFVEYARPVVTGGRRSPF