dbr1

Lariat debranching enzyme

568 amino acids

Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity).

Belongs to the lariat debranching enzyme family.

62.889 kDa

MKVAVEGCCHGELDKIYESISYLENKDGVKVDLLLCCGDFQAVRNEGDMKCMAVPAKYRHMQTFYKYYSGEKKAPVLTIFIGGNHEASNHLQELPYGGWVAPNIYYLGYAGVIRYKGVRIGGLSGIFKSHDFKKGHFEFPPYNPETLRSVYHIRNIDVFKLKQIKMPIDIFMTHDWPRGIYHYGNTNALLRQKKFLRQEVESSTLGSPAAADLLEHLQPSYWFSAHLHVKFAALMQHEAKNNTAPKITKFLSLDKCLPHRDFLQIVEVADRPGSSEQLEYDPEWLAILKATDNLQKPTCNFWNPPQDNGLHSRWDFSASEEAMMEVVSDLSGDLCIPENFSLTVPPYDPSQPQPHALPAYSTNPQTTELCATLNLTDIYILAGQSGQIYGERGGKGATEEEDEEDSTGSADEPSDFPSDTSGLSSSYNPDEITIEDEWEEEEDGGVGCGEGKGMDAVVPEGQVGSQDSDRDSSPQRETAKRLILPAPCAKPKTEAPLHSLPRLSLPPPSACVSQGSSEEEGAFTAARVPKRTSGETTQSSAGQTGGTPQIKRRNQSIYTAVEDEESDS

Dbr1

Lariat debranching enzyme

550 amino acids

Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity).

Belongs to the lariat debranching enzyme family.

62.289 kDa

MRVAVAGCCHGELDKIYETLALAERRGSGPVDLLLCCGDFQAVRNEADLRCMAVPPKYRHMQTFYRYYSGEKKAPVLTIFIGGNHEASNHLQELPYGGWVAPNIYYLGLAGVVKYRGVRIGGISGIFKSHDYRKGHFECPPYNSSTIRSIYHVRNIEVYKLKQLKQPVHIFLSHDWPRNIYHYGNKKQLLKTKSFFRQEVENSTLGSPAASELLEHLQPAYWFSAHLHVKFAALMQHQATDKDQAGKETKFLALDKCLPHRDFLQVLEIEHDPSAPEYLEYDVEWLTVLRATDDLINVTGGLWNMPEDNGLHTRWDYSATEETMKEVMEKLNHDPKVPCNFTMTAACYDPSKPQTQVKLVHRINPQTTEFCAQLGITDINVMIQKAREEEHHQCGEYEQQGDPGTEESEEDRSEYNTDTSALSSINPDEIMLDEEEEEEEEEEEAVSAHSDMNTPSVEPASDQASDLSTSFSDIRNLPSSMFVSSDDASRSPASGEGKCGETVESGDEKDLAKFPLKRLSDEHEPEQRKKIKRRNQAIYAAVDDGDASAE

DBR1

Lariat debranching enzyme

544 amino acids

Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis.

Belongs to the lariat debranching enzyme family.

61.555 kDa

MRVAVAGCCHGELDKIYETLALAERRGPGPVDLLLCCGDFQAVRNEADLRCMAVPPKYRHMQTFYRYYSGEKKAPVLTLFIGGNHEASNHLQELPYGGWVAPNIYYLGLAGVVKYRGVRIGGISGIFKSHDYRKGHFECPPYNSSTIRSIYHVRNIEVYKLKQLKQPIDIFLSHDWPRSIYHYGNKKQLLKTKSFFRQEVENNTLGSPAASELLEHLKPTYWFSAHLHVKFAALMQHQAKDKGQTARATKFLALDKCLPHRDFLQILEIEHDPSAPDYLEYDIEWLTILRATDDLINVTGRLWNMPENNGLHARWDYSATEEGMKEVLEKLNHDLKVPCNFSVTAACYDPSKPQTQMQLIHRINPQTTEFCAQLGIIDINVRLQKSKEEHHVCGEYEEQDDVESNDSGEDQSEYNTDTSALSSINPDEIMLDEEEDEDSIVSAHSGMNTPSVEPSDQASEFSASFSDVRILPGSMIVSSDDTVDSTIDREGKPGGTVESGNGEDLTKVPLKRLSDEHEPEQRKKIKRRNQAIYAAVDDDDDDAA

DBR1

Lariat debranching enzyme

537 amino acids

Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity).

Belongs to the lariat debranching enzyme family.

59.528 kDa

MKIAIEGCAHGELERIYDTIACIEKESNTKIDLLLCCGDFQSTRNLEDLQTMAVPKKYLDICTFYKYYSGECVAPVLTIFIGGNHEASNYLQELPYGGWVAPNIYYLGYAGVVNVNGVRIAGISGIYKGHDFLRGHHEFPPYTESTCRSVYHVRQLEVFRLKQLSGKIDIFLSHDWPTGIYEYGNKAQLLRKKPYFAADMESGQLGSRPLEELLKAVQPSYWFAAHLHCKFAALVPHQNATKAPTKMGDGSSSSSSSSSSESDDEESTSRLPPKPVAVTKFLALDKCLPRRAFLQVLDIPSEAIEGNPTFEYDAEWLVILQSTNHLISVKENYYYLPGKKAGAIAERFNFTPTEEELDSLTTKFQSLKIPENFQRTVPAFDPQEQSNYKHMVVGQPTAHLNPQSNTFCSVLGVDDPLCLALLANGKDLPAVADQCQDQEPIEGSSPPPEPLVTPSKRKLNLFLPAPTVTADATAAEKDDSVIDLPEEDEDPKTAETAESEAVDNPKVKAVPPPPSSPPSVKKLKRRNQNIYQAEDDD

DBR1

Lariat debranching enzyme

536 amino acids

Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity).

Belongs to the lariat debranching enzyme family.

60.777 kDa

MKVAVAGCCHGALDKMYETLELLQRRHNVRPDLLLCCGDFQAVRNEADLRCMAVPAKYRHMQTFYRYYSGEKKAPVLTVFIGGNHEASNHLQELPYGGWVAPNIYYLGYAGVVRFRGVRIGGISGIFKSHDYRKGHFECPPYNQQTIRSAYHVRNIEVFKLKQLKHPMDIFMSHDWPQSIYHYGNKKQLLKMKSFFRQEVESNTLGSPAASELLQHLKPNYWFSAHLHVKFAAFMQHETKSKEELPKATKFLALDKCLPHRDFLQIIDIEHDPTAGDSLEYDAEWIAVLKATNSLINVTQSSWSVPENNGLHAKWDYSATEEAIKEVLEELNHNLKIPCNFTLTTTCYDPSKPQKNMEPVHTINPQTTEFCAQFGLTDINDRIQQVKEEGSVRGEYEEEEEEMDSSGSAEEPSEYNTDNSGLSSINPDEIMLDDEGGDEDLSTCSVDPSPDHPPEFSASFSDIRIMPDSMAVSSDDAMDSTNEELEKSGVNKQVEEKSLNERPLKRVGGSENGNSGIKIKRRNQAIYAAEDEDEAK

dbr1

Lariat debranching enzyme

534 amino acids

Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity).

Belongs to the lariat debranching enzyme family.

60.831 kDa

MKIAVEGCCHGELDKIYETIQFLEKKENTKVDLLLCCGDFQAVRNEGDMKCMAVPQKYRQMQTFYKYYSGEKLAPILTIFIGGNHEASNYLQELPYGGWVAPNIYYVGYAGVVKYRGVRIGGISGIFKSHDYRKGHFERPPYSKDTVRSAYHVRNIEVFRLKQLKEPMDIFMSHDWPRSIYHYGNKKQLLKKKDFFRQEVENNTLGSPAASELLLHIQPSYWFSAHLHVKFAAFMQHQTNVEGEIPKATKFLALDKCLPHREFLQIVDVEHDPGKPDCLEYDLEWLAVLKATKDLLNITSKTWNMPENNGLHSRWDFSASEKTKREILDDLGHDIKIPCNFCMTTACYDPNNPQYKRVATHIVNPQTTEFCARLGLVDLNAKIRQHEEEGDIDITEDNEADSIGSAEDPGEYSTDTSLLSTSINPDEIALEDDDDQEDEGMAEKLGEPSPDYTPDLSINFSNIRVLPDSMAVSSDDATDSTNDELDRSESSQTEGEGKQSNRPLKRMSNENGSGGVKIKRRNQAIYQAKDDEDE

dbr1

Lariat debranching enzyme

478 amino acids

Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover (By similarity).

Belongs to the lariat debranching enzyme family.

54.565 kDa

MSYFARLKPPPAFLKMRVGVQGCCHGILDNLYILAEKRKVDLLIIGGDFQALRNVSDYHGISMPPKFKRLGDFFNYYNGRNKAPILTIFVGGNHEASNYLDELPYGGWVAPNIYYMGRSSVINVGGLRIAGISGIYSAMDYKKGRYEGLPYNYKMLKSIYHTREFDVLSLKSLQKPIDIFLSHDWPRGIEQHGDVAKLLRHKPFFRNEVERNDLGSPALEELLVELKPRYWMAAHLHTKFTAVVHHNSQEDDGKLSCSSKDVTSSGFSMKGLNEPSQERLPVEKEQNDKSDEEGSNNEQEEKQDKKQSTNRDLCRKESCKKEPSLSSSDQVTKFLALDKCLPRRSYFEVVEIEPVEIPDSGAPYMQYDSEWLSVLRAMHPFQSHTIEQDPPLPSLEVVKTLKRKEEIWVDENLVKKDKLGIPRNFCQTAPPHSRDITENMQPSSYINPQTVAFEILIGLKERTVDSPPPVKNPNEIVL

DBR1

Lariat debranching enzyme

418 amino acids

Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis. Plays en essential role during embryogenesis.

Belongs to the lariat debranching enzyme family.

48.175 kDa

MKIAIEGCMHGDLDNVYKTIQHYEQIHNTKVDLLLCCGDFQAVRNEKDMDSLNVPRKYREMKSFWKYYSGQEVAPIPTIFIGGNHEASNYLWELYYGGWAATNIYFLGFAGVVKFGNVRIGGLSGIYNERHYRSGHFERPPYNESTIRSVYHVRDYDVQKLMQLEEPLDIFLSHDWPVGITDYGDSESLMRQKPYFRQEIEEKTLGSKPAALLLEKLKPQYWFSAHLHCKFAAAVQHGNDGSVTKFLALDKCLPGKKFLQIIEIESEPGPFEVLYDEEWLAITRKFNSIFPLTRRYTNVSTAGTIQESREWVRKKLEERQFKPFEFARTVPAYNPSQRVFDSIPEIPQNPQTLSLLELLGLPYLLDSSPVTGERTDIPASLAPSDLPTYDSEEIPIDDIDEIEEMEEAKADDHTRDDA

DBR1

Lariat debranching enzyme

407 amino acids

Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity).

Belongs to the lariat debranching enzyme family.

46.681 kDa

MKIAVEGCMHGELDKVYDTLRELEKAEGVKIDLLLCCGDFQAVRNENDLQCLNVKPRFREMKSFWKYYSGQAVAPYPTIFIGGNHEASNYLWELYYGGWAAPNIYFLGFAGVVKFGNIRIGGLSGIYKQQHYHLGHYERPPYNENTIRSVYHVRHYDVLKLMHVKEPLDIFMSHDWPLGITEYGNWQKLIREKRFFEEEVNKRTLGSEPAARLLNKLKPPYWFSAHLHCKFPAVIQHGEGGPTTKFLALDKCLPRRGFLQVIDIPSGPGPHEIQYDEEWLAITRKFNNVFSLTRMPFTMLDEQVDTQDDLQWVRNKLNARGAKPIDFVQTAASYDPSCQASNPSITVHCRNPQTESFLQLLNLPYLLDSSNSYGVSRNESSSQTGQALDSDDIELPDDEDDPADDDD

DBR1

Lariat debranching enzyme

405 amino acids

Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It also participates in Ty1 retrovirus-like transposition via an RNA lariat intermediate in cDNA synthesis.

Belongs to the lariat debranching enzyme family.

47.741 kDa

MTKLRIAVQGCCHGQLNQIYKEVSRIHAKTPIDLLIILGDFQSIRDGQDFKSIAIPPKYQRLGDFISYYNNEIEAPVPTIFIGGNHESMRHLMLLPHGGYVAKNIFYMGYSNVIWFKGIRIGSLSGIWKEWDFNKQRPDWNDLENNNWKANIRNLYHVRISDIAPLFMIKHRIDIMLSHDWPNGVVYHGDTKHLLKLKPFFEQDIKEGKLGSPVTWQLLRDLRPQWWLSAHLHVRFMASIKHNKRSHEPPNKSTSKTKKNNNEIDLDLSSDEDERSGIMNCQEENEYDSKYGETRFLALDKCLPRRRWLEILEIEPDTSHASWKDENHRMFWDPEFINNLVICQKNKNLLSNKPFNSVNWIELSQSNREEGRDIDWENYAIPAYTLDIQKDEVRQTKAFISKFMT