DAW1

Gene

DAW1

Protein

Dynein assembly factor with WDR repeat domains 1

Organism

Chlamydomonas reinhardtii

Length

446 amino acids

Function

Functions as a cargo-specific adapter between intraflagellar transport (IFT) particles and outer row dynein. Required for efficient dynein-mediated transport into the flagellar compartment.

Mass

49.25 kDa

Sequence

MAAKLRKFLLRYYPPGIILQYERDGVMKQKPIDLLDLTPDVDVEVLLSQIIRQEPLISENRRPALRQLIHRLIDKMLEQQHHSFTLFKVLRAHILPLTNCAFNKSGDRFITGSYDRTCKVWNTFTGEEVFTLEGHKNVVYAIAFNNPYGDKIVTGSFDKTCKLWDAYTGQLYYTLKGHQTEIVCLSFNPQSTIIATGSMDNTAKLWDVETGQERATLAGHRAEIVSLGFNTGGDLIVTGSFDHDSRLWDVRTGQCVHVLSGHRGEVSSTQFNYAGTLVVSGSIDCTSRLWDVRSGRCLSVKQGHTDEVLDVAFDAAGTKMVSASADGSARLYHTLTGVCQHTLVGHEGEISKVAFNPQGTRLITASSDKTCRLWDCDTGECLQVLEGHTDEIFSCAFNYEGDFIITGSKDNTCRIWKALTASSQPAGPGGAGGGLARPTTAFSYND

Protein

Dynein assembly factor with WDR repeat domains 1: DAW1

Gene

DAW1

Protein

Dynein assembly factor with WDR repeat domains 1

Organism

Bos taurus

Length

415 amino acids

Function

May play a role in axonemal outer row dynein assembly.

Similarity

Belongs to the WD repeat WDR69 family.

Mass

45.857 kDa

Sequence

MKLKSLLLRYYPPGIMLEYEKSGQLKTKSIDLLDLDPSTDVSALVEEIQKAEPLITASRSDQVKLLIQRLQNKLGQHSNHKFYLFKVLRAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELHTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQSGEEVFTLTGHSAEIISLSFNTSGNRIITGSFDHTVTVWEADTGRKVYTLIGHCAEISSAVFNWDCSLILTGSMDKTCKLWDAVNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRECVTKLEGHEGEISKISFNPQGNRLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGDIIITGSKDNTCRIWR

Protein

Dynein assembly factor with WDR repeat domains 1: DAW1

Gene

daw1

Protein

Dynein assembly factor with WDR repeat domains 1

Organism

Danio rerio

Length

415 amino acids

Function

Required for axonemal dynein assembly and ciliary motility in ciliated organs, including Kupffer's vesicle, during embryogenesis.

Similarity

Belongs to the WD repeat WDR69 family.

Mass

45.934 kDa

Sequence

MRLKRMHIRYYPPGIFLDYEKGGQLRTKCIDLLNLTPETDVEELVLEIRAAEPLITSSCVEQVKLLICKLQEKVGQKDERKFYLFRALQAHILPLTNVAFNKSGSCFITGSYDRTCKIWDTASGEELHTLEGHRNVVYAIAFNNPYGDKVATGSFDKTCKLWSAETGKCFYTFRGHTAEIVCLAFNPQSTLVATGSMDTTAKLWDVESGEEVSTLAGHFAEIISLCFNTTGDRLVTGSFDHTAILWDVPSGRKVHVLSGHRGEISCVQFNWDCSLIATASLDKSCKVWDAEGGQCLATLLGHNDEVLDVCFNYTGQLIATASADGTSRVFSTDTFQCLCQLEGHKGEISKVCFNAQGSRVLTASVDKTSRVWCVKTGACLQVLEGHSDEIFSCAFNYEGDTIITGSKDNTCRIWH

Protein

Dynein assembly factor with WDR repeat domains 1: daw1

Gene

DAW1

Protein

Dynein assembly factor with WDR repeat domains 1

Organism

Homo sapiens

Length

415 amino acids

Function

May play a role in axonemal outer row dynein assembly.

Similarity

Belongs to the WD repeat WDR69 family.

Mass

45.777 kDa

Sequence

MKLKSLLLRYYPPGIMLEYEKHGELKTKSIDLLDLGPSTDVSALVEEIQKAEPLLTASRTEQVKLLIQRLQEKLGQNSNHTFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIWR

Protein

Dynein assembly factor with WDR repeat domains 1: DAW1

Gene

DAW1

Protein

Dynein assembly factor with WDR repeat domains 1

Organism

Macaca fascicularis

Length

415 amino acids

Function

May play a role in axonemal outer row dynein assembly.

Similarity

Belongs to the WD repeat WDR69 family.

Mass

45.74 kDa

Sequence

MKLKSFLLRYYPPGIMLEYEKHGELKTKSIDLLDLGPSTDVSALVEEIQKAEPLITASRTEQVKLLIQRLQEKLGQHSNHTFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKTATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWNIQNGEEVCTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGGKVNILIGHCAEISSALFNWDCSLILTGSMDKTCMLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNRLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCTFNYKGNIVITGSKDNTCRIWR

Protein

Dynein assembly factor with WDR repeat domains 1: DAW1

Gene

Daw1

Protein

Dynein assembly factor with WDR repeat domains 1

Organism

Rattus norvegicus

Length

415 amino acids

Function

May play a role in axonemal outer row dynein assembly.

Similarity

Belongs to the WD repeat WDR69 family.

Mass

45.859 kDa

Sequence

MKLKSLLLRYYPPGIMLEYEKGGELKTKSIDLLELSPSTDVNTLVGEIQKVEPLITASRTKQVRLLVQRLQEKLRQHCDHNFYLFKVLRAHILPLTNVALNKAGSCFITGSYDRTCKVWDTASGEELHTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSAETGKCYHTFRGHTAEIVCLSFNPQSTVVATGSMDTTAKLWDIQSGEEVVTLTGHLAEIISLSFDTSGDRIITGSFDHTVVVWDASTGRKVHTLIGHCAEISSALFSWDCSLILTGSMDKTCMLWDATSGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARVYNATTRKCITKLEGHEGEISKISFNPQGNRLLTGSSDKTARIWDVQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNSCRIWR

Protein

Dynein assembly factor with WDR repeat domains 1: Daw1

Gene

daw1

Protein

Dynein assembly factor with WDR repeat domains 1

Organism

Xenopus laevis

Length

415 amino acids

Function

May play a role in axonemal outer row dynein assembly.

Similarity

Belongs to the WD repeat WDR69 family.

Mass

45.918 kDa

Sequence

MRLKRFLLRYFPPGIILEYEKGGELKTKAIDLLELSPTTDVDLVVGEIQKAEPLITASRTQQVKQLILRLQEKIGQQDSRQFYLFKVLRAHILPLTNVAFNKSGSSFITGSYDRTCKVWDTASGEELHTLEGHRNVVYAIQFNNPYGDKIATGSFDKTCKLWSAETGKCYHTFRGHTAEIVCLVFNPQSTLIATGSMDTTAKLWDIQSGEEALTLSGHAAEIISLSFNTTGDRLITGSFDHTVSVWEIPSGRRIHTLIGHRGEISSAQFNWDCSLIATASMDKSCKLWDSLNGKCVATLTGHDDEVLDVTFDSTGQLVATASADGTARVYSASSRKCLAKLEGHEGEISKICFNAQGNRIVTASSDKTSRLWDPHTGECLQVLKGHTDEIFSCAFNYEGNTIITGSKDNTCRIWR

Protein

Dynein assembly factor with WDR repeat domains 1: daw1