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DAO

Gene
DAO
Protein
D-amino-acid oxidase
Organism
Cavia porcellus
Length
347 amino acids
Function
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids (By similarity).
Similarity
Belongs to the DAMOX/DASOX family.
Mass
39.284 kDa
Sequence
MRVVVIGAGVIGLSTALCICERYHSVLQQLDLRVYADRFTPLTNTDVAAGLWQPYLSGPDNPQEVEWNQQTFDYLLSHIHSPNAEQMGLALVSGYNLFREAVPDPFWKNMVLGFRKLTPRELDVFPDYGYGWFHTSLIIEGKSYLAWLTERLTERGVKFFQRKVESLEEVARGGADVIINCTGVWAGALQPDPLLQPGRGQIIKVNAPWIKHFILTHDPERGIYKSPYIIPGIQEVTLGGIFQLGNWNEINSTQDHNTIWKGCCSLEPTLRNARIVGEYTGFRPVRPQLRLEREQLRVGSANTEVIHNYGHGGYGLTIHWGCALEAAKLFGKILEEKELYRMPPSHL

Gene
DAO
Protein
D-amino-acid oxidase
Organism
Homo sapiens
Length
347 amino acids
Function
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.
Similarity
Belongs to the DAMOX/DASOX family.
Mass
39.474 kDa
Sequence
MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPNNPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPRELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVNCTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGGIFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGPSNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL

Gene
DAO
Protein
D-amino-acid oxidase
Organism
Macaca fascicularis
Length
347 amino acids
Function
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids (By similarity).
Similarity
Belongs to the DAMOX/DASOX family.
Mass
39.413 kDa
Sequence
MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGFWQPYLSDPSNPKEADWSQQTFDHLLSHIHSPNAEKLGLFLISGYNLFHEAIPNPSWKDTVLGFRKLTPRELDIFPDYSYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVNCTGVWAGVLQPDPLLQPGRGQIIKVDAPWIKHFILTHEPESGIYNSPYIIPGTQTVTLGGIFQLGNWNELNNIQDHNTIWEGCCRLEPTLKNARIVDERTGFRPVRPKIRLEREQLRVGPSNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSKMPPSHL

Gene
DAO
Protein
D-amino-acid oxidase
Organism
Sus scrofa
Length
347 amino acids
Function
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.
Similarity
Belongs to the DAMOX/DASOX family.
Mass
39.336 kDa
Sequence
MRVVVIGAGVIGLSTALCIHERYHSVLQPLDVKVYADRFTPFTTTDVAAGLWQPYTSEPSNPQEANWNQQTFNYLLSHIGSPNAANMGLTPVSGYNLFREAVPDPYWKDMVLGFRKLTPRELDMFPDYRYGWFNTSLILEGRKYLQWLTERLTERGVKFFLRKVESFEEVARGGADVIINCTGVWAGVLQPDPLLQPGRGQIIKVDAPWLKNFIITHDLERGIYNSPYIIPGLQAVTLGGTFQVGNWNEINNIQDHNTIWEGCCRLEPTLKDAKIVGEYTGFRPVRPQVRLEREQLRFGSSNTEVIHNYGHGGYGLTIHWGCALEVAKLFGKVLEERNLLTMPPSHL

Gene
DAO
Protein
D-amino-acid oxidase
Organism
Oryctolagus cuniculus
Length
347 amino acids
Function
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids (By similarity).
Similarity
Belongs to the DAMOX/DASOX family.
Mass
38.59 kDa
Sequence
MRVVVIGAGVIGLSTALCIHELYHSALQPLDMTIYADRFTPLTNTDVAAGLWQPYLSDPSNPQEADWSRQTFNHLLSHIHSPSAEKMGLALISGYNLFRKAVPDPSWKDTVLGFRKLTLRELDMFPGYSYGWFNTSLILDGRSYLQWLTKRLTERGVKLFQRKVESFDEVAGGGVDVIVNCTGVWASALQPDPLLQPGRGQIIKVDAPWVKHFIITHDPESGIYKSPYIIPGVHAVTLGGIFQMGNWSEGNSTDDHNTIWKGCCSLEPTLKDARIVGEWTGFRPVRPQIRLGREQLSAGPSKTEVIHNYGHGGYGLTIHWGCALEAAKLFGKILEEKKSSRMPPSHL

Gene
DAO
Protein
D-amino-acid oxidase
Organism
Cricetulus griseus
Length
346 amino acids
Function
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids (By similarity).
Similarity
Belongs to the DAMOX/DASOX family.
Mass
39.146 kDa
Sequence
MRVVVIGAGVIGLSTALCIHERFSPVQPLHMKIYADRFTPFTTSDVAAGFWQPYLSDPRNPQEVEWNQQTFDYLLSHIHSPNAEKMGLSLISGYNLFKEEVPDPFWRNTVLGFRKLTPREMDIFPDYGYGWFNTSLTLEGKSYLPWLTERLTERGVKLFHRKVESFEEVARGGADVIINCTGVWAGALQADTSLQPGRGQIIQVEAPWMKHFILTHDPRLGIYNSPYIIPGSKTVTLGGVFQLGNWNELNSVHDHNTIWKSCCKLEPTLKNAKIVGELTGFRPVRHQVRLKKKQLHFGSSSVEVIHNYGHGGYGLTIHWGCAMEAANLFGKILEEKKLSRMPASHL

Gene
Dao
Protein
D-amino-acid oxidase
Organism
Rattus norvegicus
Length
346 amino acids
Function
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.
Similarity
Belongs to the DAMOX/DASOX family.
Mass
38.82 kDa
Sequence
MRVAVIGAGVIGLSTALCIHERYHPAQPLHMKIYADRFTPFTTSDVAAGLWQPYLSDPSNPQEAEWNQQTFDHLQSCLHSPNAEKMGLALISGYNLFRDEVPDPFWKSTVLGFRKLTPSELDMFPDYSYGWFNTSLLLEGKSYLSWLTERLTERGVKFIHRKVASFEEVVRGGVDVIINCTGVWAGALQADASLQPGRGQIIQVEAPWIKHFILTHDPSLGIYNSPYIIPGSKTVTLGGVFQLGNWSELNSVHDHNTIWKSCCQLEPTLKNARIMGELTGFRPVRPQVRLERERLRFGSSSAEVIHNYGHGGYGLTIHWGCAMEAANLFGKILEEKNLSRMPPSHL

Gene
Dao
Protein
D-amino-acid oxidase
Organism
Mus musculus
Length
345 amino acids
Function
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.
Similarity
Belongs to the DAMOX/DASOX family.
Mass
38.661 kDa
Sequence
MRVAVIGAGVIGLSTALCIHERYHPTQPLHMKIYADRFTPFTTSDVAAGLWQPYLSDPSNPQEAEWSQQTFDYLLSCLHSPNAEKMGLALISGYNLFRDEVPDPFWKNAVLGFRKLTPSEMDLFPDYGYGWFNTSLLLEGKSYLPWLTERLTERGVKLIHRKVESLEEVARGVDVIINCTGVWAGALQADASLQPGRGQIIQVEAPWIKHFILTHDPSLGIYNSPYIIPGSKTVTLGGIFQLGNWSGLNSVRDHNTIWKSCCKLEPTLKNARIVGELTGFRPVRPQVRLEREWLRHGSSSAEVIHNYGHGGYGLTIHWGCAMEAANLFGKILEEKKLSRLPPSHL

Gene
DAO
Protein
2-oxoglutarate-dependent dioxygenase DAO
Organism
Oryza sativa subsp. indica
Length
300 amino acids
Function
2-oxoglutarate-dependent dioxygenase essential for auxin catabolism and maintenance of auxin homeostasis in reproductive organs. Catalyzes the irreversible oxidation of indole-3-acetic acid (IAA) to the biologically inactive 2-oxoindole-3-acetic acid (OxIAA) (By similarity).
Similarity
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Mass
32.102 kDa
Sequence
MVEIPAIDLRLAGGGGGAEETARLRDACARLGCFRVSGHGVPPGLQAEMKAAVRALFDLPDDAKRRNADIIPGSGYVPPGTANPLYEAFGLCDAAAPADVDAFCARLDAPPHVRETVKAYAERMHSLIVDVAGKVAASLGLHGASFQDWPCQFRMNRYNYTQDSVGSPGVQVHTDSGFLTVLQEDECVGGLEVLDPAAGEFVPVDPLPGSFVVNVGDVGQAWSNGRLHNVKHRVQCVAAVPRVSIAMFLLAPKDDTVSAPGELVDGEHPRRYREFKYDDYRRLRLSTGERAGEALARLAA

Gene
DAO
Protein
2-oxoglutarate-dependent dioxygenase DAO
Organism
Oryza sativa subsp. japonica
Length
300 amino acids
Function
2-oxoglutarate-dependent dioxygenase essential for auxin catabolism and maintenance of auxin homeostasis in reproductive organs. Catalyzes the irreversible oxidation of indole-3-acetic acid (IAA) to the biologically inactive 2-oxoindole-3-acetic acid (OxIAA).
Similarity
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Mass
32.102 kDa
Sequence
MVEIPAIDLRLAGGGGGAEETARLRDACARLGCFRVSGHGVPPGLQAEMKAAVRALFDLPDDAKRRNADIIPGSGYVPPGTANPLYEAFGLCDAAAPADVDAFCARLDAPPHVRETVKAYAERMHSLIVDVAGKVAASLGLHGASFQDWPCQFRMNRYNYTQDSVGSPGVQVHTDSGFLTVLQEDECVGGLEVLDPAAGEFVPVDPLPGSFVVNVGDVGQAWSNGRLHNVKHRVQCVAAVPRVSIAMFLLAPKDDTVSAPGELVDGEHPRRYREFKYDDYRRLRLSTGERAGEALARLAA